PDB: 3246 件ウェブページステータス検索Chemie searchBIRD

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3SCF	Fe(II)-HppE with S-HPP and NO 分子名称: (S)-2-HYDROXYPROPYLPHOSPHONIC ACID, Epoxidase, FE (II) ION, ... 著者 Drennan, C.L. 登録日 2011-06-07 公開日 2011-07-06 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.85 Å) 主引用文献 Structural basis of regiospecificity of a mononuclear iron enzyme in antibiotic fosfomycin biosynthesis. J.Am.Chem.Soc., 133, 2011
4UFT	Structure of the helical Measles virus nucleocapsid 分子名称: 5'-R(*CP*CP*CP*CP*CP*CP)-3', NUCLEOPROTEIN 著者 Gutsche, I, Desfosses, A, Effantin, G, Ling, W.L, Haupt, M, Ruigrok, R.W.H, Sachse, C, Schoehn, G. 登録日 2015-03-19 公開日 2015-04-29 最終更新日 2024-05-08 実験手法 ELECTRON MICROSCOPY (4.3 Å) 主引用文献 Near-Atomic Cryo-Em Structure of the Helical Measles Virus Nucleocapsid. Science, 348, 2015
7RTY	Crystal Structure of PsfC from Pseudomonas syringae PB-5123 分子名称: FE (II) ION, PsfC 著者 Ongpipattanakul, C, Nair, S.K. 登録日 2021-08-16 公開日 2021-09-15 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (1.963 Å) 主引用文献 Biosynthesis of fosfomycin in pseudomonads reveals an unexpected enzymatic activity in the metallohydrolase superfamily. Proc.Natl.Acad.Sci.USA, 118, 2021
3A06	Crystal structure of DXR from Thermooga maritia, in complex with fosmidomycin and NADPH 分子名称: 1-deoxy-D-xylulose 5-phosphate reductoisomerase, 3-[FORMYL(HYDROXY)AMINO]PROPYLPHOSPHONIC ACID, MAGNESIUM ION, ... 著者 Takenoya, M, Ohtaki, A, Noguchi, K, Sasaki, Y, Ohsawa, K, Yohda, M, Yajima, S. 登録日 2009-03-02 公開日 2010-03-16 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Crystal structure of 1-deoxy-d-xylulose 5-phosphate reductoisomerase from the hyperthermophile Thermotoga maritima for insights into the coordination of conformational changes and an inhibitor binding J.Struct.Biol., 170, 2010
8ZXX	PfDXR - Mn2+ - NADPH - TAKK442 quaternary complex 分子名称: 1-deoxy-D-xylulose 5-phosphate reductoisomerase, apicoplastic, GLYCEROL, ... 著者 Tanaka, N, Takada, S, Sakamoto, Y. 登録日 2024-06-15 公開日 2025-05-21 実験手法 X-RAY DIFFRACTION (1.23 Å) 主引用文献 Expanding the Chemical Space of Reverse Fosmidomycin Analogs. Acs Med.Chem.Lett., 16, 2025
5ZDN	The complex structure of FomD with CDP 分子名称: CYTIDINE-5'-DIPHOSPHATE, FomD, GLYCEROL, ... 著者 Sato, S, Miyanaga, A, Kudo, F, Eguchi, T. 登録日 2018-02-23 公開日 2018-07-25 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.02 Å) 主引用文献 Biochemical and Structural Analysis of FomD That Catalyzes the Hydrolysis of Cytidylyl ( S)-2-Hydroxypropylphosphonate in Fosfomycin Biosynthesis. Biochemistry, 57, 2018
5ZDM	The ligand-free structure of FomD 分子名称: CALCIUM ION, FomD, GLYCEROL 著者 Sato, S, Miyanaga, A, Kudo, F, Eguchi, T. 登録日 2018-02-23 公開日 2018-07-25 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.38 Å) 主引用文献 Biochemical and Structural Analysis of FomD That Catalyzes the Hydrolysis of Cytidylyl ( S)-2-Hydroxypropylphosphonate in Fosfomycin Biosynthesis. Biochemistry, 57, 2018
9BU5	CC ProXp-ala apo solution structure 分子名称: DNA-binding protein, putative 著者 Duran, A.D, Foster, M.P. 登録日 2024-05-16 公開日 2024-10-16 最終更新日 2024-11-13 実験手法 SOLUTION NMR 主引用文献 NMR-based solution structure of the Caulobacter crescentus ProXp-ala trans-editing enzyme. Biomol.Nmr Assign., 18, 2024
4AIC	X-ray structure of 1-deoxy-D-xylulose 5-phosphate reductoisomerase, DXR, Rv2870c, from Mycobacterium tuberculosis, in complex with fosmidomycin, manganese and NADPH 分子名称: 1-DEOXY-D-XYLULOSE 5-PHOSPHATE REDUCTOISOMERASE, 3-[FORMYL(HYDROXY)AMINO]PROPYLPHOSPHONIC ACID, MANGANESE (II) ION, ... 著者 Henriksson, L.M, Unge, T, Jones, T.A, Mowbray, S.L. 登録日 2012-02-09 公開日 2012-02-22 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Structures of Mycobacterium Tuberculosis 1-Deoxy-D-Xylulose- 5-Phosphate Reductoisomerase Provide New Insights Into Catalysis. J.Biol.Chem., 282, 2007
9BE7	Alkalihalobacillus halodurans (Aha) trp RNA binding attenuation protein (TRAP) mutant dTRAP without Trp 分子名称: Transcription attenuation protein MtrB 著者 Yang, H, Stachowski, K, Foster, M. 登録日 2024-04-15 公開日 2025-01-22 実験手法 ELECTRON MICROSCOPY (4.24 Å) 主引用文献 Structural basis of nearest-neighbor cooperativity in the ring-shaped gene regulatory protein TRAP from protein engineering and cryo-EM. Proc.Natl.Acad.Sci.USA, 122, 2025
9BE8	Alkalihalobacillus halodurans (Aha) trp RNA binding attenuation protein (TRAP) mutant T49A/T52A dTRAP with Trp 分子名称: TRYPTOPHAN, Transcription attenuation protein MtrB 著者 Yang, H, Stachowski, K, Foster, M. 登録日 2024-04-15 公開日 2025-01-22 最終更新日 2025-05-21 実験手法 ELECTRON MICROSCOPY (4.14 Å) 主引用文献 Structural basis of nearest-neighbor cooperativity in the ring-shaped gene regulatory protein TRAP from protein engineering and cryo-EM. Proc.Natl.Acad.Sci.USA, 122, 2025
9BDS	Alkalihalobacillus halodurans (Aha) trp RNA binding attenuation protein (TRAP) mutant dTRAP with Trp 分子名称: TRYPTOPHAN, Transcription attenuation protein MtrB 著者 Yang, H, Stachowski, K, Foster, M. 登録日 2024-04-12 公開日 2025-01-22 実験手法 ELECTRON MICROSCOPY (3.6 Å) 主引用文献 Structural basis of nearest-neighbor cooperativity in the ring-shaped gene regulatory protein TRAP from protein engineering and cryo-EM. Proc.Natl.Acad.Sci.USA, 122, 2025
5NUG	Motor domains from human cytoplasmic dynein-1 in the phi-particle conformation 分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Cytoplasmic dynein 1 heavy chain 1, ... 著者 Zhang, K, Foster, H.E, Carter, A.P. 登録日 2017-04-30 公開日 2017-06-28 最終更新日 2024-05-15 実験手法 ELECTRON MICROSCOPY (3.8 Å) 主引用文献 Cryo-EM Reveals How Human Cytoplasmic Dynein Is Auto-inhibited and Activated. Cell, 169, 2017
5I3U	STRUCTURE OF HIV-1 REVERSE TRANSCRIPTASE N-SITE COMPLEX; CATALYTIC INCORPORATION OF AZTMP to A DNA aptamer in CRYSTAL 分子名称: DNA (39-MER), GLYCEROL, HIV-1 REVERSE TRANSCRIPTASE P51 SUBUNIT, ... 著者 Das, K, Arnold, E. 登録日 2016-02-11 公開日 2016-06-01 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Conformational States of HIV-1 Reverse Transcriptase for Nucleotide Incorporation vs Pyrophosphorolysis-Binding of Foscarnet. Acs Chem.Biol., 11, 2016
5NVU	Full length human cytoplasmic dynein-1 in the phi-particle conformation 分子名称: Dynein intermediate chain, Dynein light intermediate chain, Dynein motor domain, ... 著者 Zhang, K, Foster, H.E, Carter, A.P. 登録日 2017-05-04 公開日 2017-08-09 最終更新日 2024-10-23 実験手法 ELECTRON MICROSCOPY (15 Å) 主引用文献 Cryo-EM Reveals How Human Cytoplasmic Dynein Is Auto-inhibited and Activated. Cell, 169, 2017
5NVS	Human cytoplasmic dynein-1 tail in the twisted N-terminus state 分子名称: LC8, N-terminal dimerization domain, Robl, ... 著者 Zhang, K, Foster, H.E, Carter, A.P. 登録日 2017-05-04 公開日 2017-06-28 最終更新日 2024-07-10 実験手法 ELECTRON MICROSCOPY (8.4 Å) 主引用文献 Cryo-EM Reveals How Human Cytoplasmic Dynein Is Auto-inhibited and Activated. Cell, 169, 2017
5NW4	Human cytoplasmic dynein-1 bound to dynactin and an N-terminal construct of BICD2 分子名称: Arp1, Arp11, BICD2N, ... 著者 Zhang, K, Foster, H.E, Carter, A.P. 登録日 2017-05-05 公開日 2017-08-02 最終更新日 2024-11-13 実験手法 ELECTRON MICROSCOPY (8.7 Å) 主引用文献 Cryo-EM Reveals How Human Cytoplasmic Dynein Is Auto-inhibited and Activated. Cell, 169, 2017
6ZGZ	Structure of human galactokinase 1 bound with 2-(4-chlorophenyl)-N-(pyrimidin-2-yl)acetamide 分子名称: 2-(1,3-benzoxazol-2-ylamino)spiro[1,6,7,8-tetrahydroquinazoline-4,1'-cyclohexane]-5-one, Galactokinase, beta-D-galactopyranose, ... 著者 Mackinnon, S.R, Bezerra, G.A, Zhang, M, Foster, W, Krojer, T, Brandao-Neto, J, Douangamath, A, Arrowsmith, C, Edwards, A, Bountra, C, Brennan, P, Lai, K, Yue, W.W. 登録日 2020-06-20 公開日 2020-07-29 最終更新日 2024-10-09 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Fragment Screening Reveals Starting Points for Rational Design of Galactokinase 1 Inhibitors to Treat Classic Galactosemia. Acs Chem.Biol., 16, 2021
6ZGX	Structure of human galactokinase 1 bound with 2-(4-chlorophenyl)-N-(pyrimidin-2-yl)acetamide 分子名称: 1-[2-(2-oxidanylidenepyrrolidin-1-yl)ethyl]-3-phenyl-urea, 2-(1,3-benzoxazol-2-ylamino)spiro[1,6,7,8-tetrahydroquinazoline-4,1'-cyclohexane]-5-one, Galactokinase, ... 著者 Mackinnon, S.R, Bezerra, G.A, Zhang, M, Foster, W, Krojer, T, Brandao-Neto, J, Douangamath, A, Arrowsmith, C, Edwards, A, Bountra, C, Brennan, P, Lai, K, Yue, W.W. 登録日 2020-06-20 公開日 2020-07-29 最終更新日 2024-11-06 実験手法 X-RAY DIFFRACTION (1.86 Å) 主引用文献 Fragment Screening Reveals Starting Points for Rational Design of Galactokinase 1 Inhibitors to Treat Classic Galactosemia. Acs Chem.Biol., 16, 2021
6ZGY	Structure of human galactokinase 1 bound with 2-(4-chlorophenyl)-N-(pyrimidin-2-yl)acetamide 分子名称: (2,5-dimethylphenyl) pyridine-4-carboxylate, 2-(1,3-benzoxazol-2-ylamino)spiro[1,6,7,8-tetrahydroquinazoline-4,1'-cyclohexane]-5-one, Galactokinase, ... 著者 Mackinnon, S.R, Bezerra, G.A, Zhang, M, Foster, W, Krojer, T, Brandao-Neto, J, Douangamath, A, Arrowsmith, C, Edwards, A, Bountra, C, Brennan, P, Lai, K, Yue, W.W. 登録日 2020-06-20 公開日 2020-07-29 最終更新日 2024-11-06 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Fragment Screening Reveals Starting Points for Rational Design of Galactokinase 1 Inhibitors to Treat Classic Galactosemia. Acs Chem.Biol., 16, 2021
5I42	Structure of HIV-1 Reverse Transcriptase in complex with a DNA aptamer, AZTTP, and CA(2+) ion 分子名称: 3'-AZIDO-3'-DEOXYTHYMIDINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA (38-MER), ... 著者 Das, K, Arnold, E. 登録日 2016-02-11 公開日 2016-06-01 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (3.3 Å) 主引用文献 Conformational States of HIV-1 Reverse Transcriptase for Nucleotide Incorporation vs Pyrophosphorolysis-Binding of Foscarnet. Acs Chem.Biol., 11, 2016
5HRO	STRUCTURE OF HIV-1 REVERSE TRANSCRIPTASE In COMPLEX WITH A DNA aptamer and an Alpha-carboxy nucleoside phosphonate inhibitor (alpha-CNP) 分子名称: DNA (38-MER), HIV-1 REVERSE TRANSCRIPTASE P51 SUBUNIT, HIV-1 REVERSE TRANSCRIPTASE P66 SUBUNIT, ... 著者 Das, K, Arnold, E. 登録日 2016-01-23 公開日 2016-06-01 最終更新日 2024-12-25 実験手法 X-RAY DIFFRACTION (2.75 Å) 主引用文献 Conformational States of HIV-1 Reverse Transcriptase for Nucleotide Incorporation vs Pyrophosphorolysis-Binding of Foscarnet. Acs Chem.Biol., 11, 2016
3WQQ	Crystal structure of PfDXR complexed with inhibitor-3 分子名称: 1-deoxy-D-xylulose 5-phosphate reductoisomerase, apicoplast, CALCIUM ION, ... 著者 Tanaka, N, Umeda, T. 登録日 2014-01-31 公開日 2014-11-26 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 Binding Modes of Reverse Fosmidomycin Analogs toward the Antimalarial Target IspC. J.Med.Chem., 57, 2014
3WQS	Crystal structure of pfdxr complexed with inhibitor-126 分子名称: 1-deoxy-D-xylulose 5-phosphate reductoisomerase, apicoplast, MAGNESIUM ION, ... 著者 Tanaka, N, Umeda, T. 登録日 2014-01-31 公開日 2014-11-26 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 Binding Modes of Reverse Fosmidomycin Analogs toward the Antimalarial Target IspC. J.Med.Chem., 57, 2014
3AUA	Crystal structure of the quaternary complex-2 of an isomerase 分子名称: 1-deoxy-D-xylulose 5-phosphate reductoisomerase, 3-[ethanoyl(hydroxy)amino]propylphosphonic acid, CALCIUM ION, ... 著者 Umeda, T, Tanaka, N, Kusakabe, Y, Nakanishi, M, Kitade, Y, Nakamura, K.T. 登録日 2011-02-01 公開日 2011-08-10 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Molecular basis of fosmidomycin's action on the human malaria parasite Plasmodium falciparum Sci Rep, 1, 2011

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