5NW4

Human cytoplasmic dynein-1 bound to dynactin and an N-terminal construct of BICD2

Summary for 5NW4

• Entry DOI: 10.2210/pdb5nw4/pdb
• EMDB information: 3698 3703 3704 3705 3706
• Descriptor: dynein heavy chain, Arp1, beta-actin, ... (28 entities in total)
• Functional Keywords: motor protein, dynein, dynactin, bicd
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 39
• Total formula weight: 1095055.14

Authors

Zhang, K.,Foster, H.E.,Carter, A.P. (deposition date: 2017-05-05, release date: 2017-08-02, Last modification date: 2018-11-21)

• Primary citation: Zhang, K.,Foster, H.E.,Rondelet, A.,Lacey, S.E.,Bahi-Buisson, N.,Bird, A.W.,Carter, A.P.; Cryo-EM Reveals How Human Cytoplasmic Dynein Is Auto-inhibited and Activated.; Cell, 169:1303-1314.e18, 2017; PubMed: 28602352; DOI: 10.1016/j.cell.2017.05.025

Experimental method

ELECTRON MICROSCOPY (8.7 Å)