5NW4

Human cytoplasmic dynein-1 bound to dynactin and an N-terminal construct of BICD2

Functional Information from GO Data

Chain	GOid	namespace	contents
g	0000776	cellular_component	kinetochore
g	0005813	cellular_component	centrosome
g	0005856	cellular_component	cytoskeleton
g	0005869	cellular_component	dynactin complex
g	0007017	biological_process	microtubule-based process
g	0007052	biological_process	mitotic spindle organization
g	0015630	cellular_component	microtubule cytoskeleton
g	0070840	molecular_function	dynein complex binding
h	0000776	cellular_component	kinetochore
h	0005515	molecular_function	protein binding
h	0005813	cellular_component	centrosome
h	0005829	cellular_component	cytosol
h	0005856	cellular_component	cytoskeleton
h	0005869	cellular_component	dynactin complex
l	0005737	cellular_component	cytoplasm
l	0005869	cellular_component	dynactin complex
l	0007017	biological_process	microtubule-based process
l	0030286	cellular_component	dynein complex
V	0000166	molecular_function	nucleotide binding
V	0005524	molecular_function	ATP binding
V	0005856	cellular_component	cytoskeleton
X	0005200	molecular_function	structural constituent of cytoskeleton
X	0005634	cellular_component	nucleus
X	0005856	cellular_component	cytoskeleton
X	0005869	cellular_component	dynactin complex
X	0007010	biological_process	cytoskeleton organization
X	0007017	biological_process	microtubule-based process
X	0098958	biological_process	retrograde axonal transport of mitochondrion
X	1904115	cellular_component	axon cytoplasm
Y	0003779	molecular_function	actin binding
Y	0005829	cellular_component	cytosol
Y	0005856	cellular_component	cytoskeleton
Y	0007017	biological_process	microtubule-based process
Y	0008290	cellular_component	F-actin capping protein complex
Y	0015629	cellular_component	actin cytoskeleton
Y	0030036	biological_process	actin cytoskeleton organization
Y	0030863	cellular_component	cortical cytoskeleton
Y	0051015	molecular_function	actin filament binding
Y	0051016	biological_process	barbed-end actin filament capping
Y	0051693	biological_process	actin filament capping
Z	0003779	molecular_function	actin binding
Z	0005737	cellular_component	cytoplasm
Z	0005856	cellular_component	cytoskeleton
Z	0008290	cellular_component	F-actin capping protein complex
Z	0030036	biological_process	actin cytoskeleton organization
Z	0051016	biological_process	barbed-end actin filament capping
Z	0051693	biological_process	actin filament capping

Functional Information from PROSITE/UniProt

site_id	PS00231
Number of Residues	6
Details	F_ACTIN_CAPPING_BETA F-actin capping protein beta subunit signature. CDYNRD

Chain	Residue	Details
Z	CYS62-ASP67

---

site_id	PS00406
Number of Residues	11
Details	ACTINS_1 Actins signature 1. YVGDEAQs.KRG

Chain	Residue	Details
V	TYR53-GLY63

---

site_id	PS00432
Number of Residues	9
Details	ACTINS_2 Actins signature 2. WISKqEYDE

Chain	Residue	Details
V	TRP356-GLU364
G	TRP357-GLU365

---

site_id	PS00748
Number of Residues	9
Details	F_ACTIN_CAPPING_A_1 F-actin capping protein alpha subunit signature 1. VHYYEDGNV

Chain	Residue	Details
Y	VAL196-VAL204

---

site_id	PS00749
Number of Residues	11
Details	F_ACTIN_CAPPING_A_2 F-actin capping protein alpha subunit signature 2. KaLRRqLPVTR

Chain	Residue	Details
Y	LYS256-ARG266

---

site_id	PS01132
Number of Residues	13
Details	ACTINS_ACT_LIKE Actins and actin-related proteins signature. LLTEApLNPkaNR

Chain	Residue	Details
V	LEU104-ARG116
G	LEU109-ARG121

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"UniProtKB","id":"P52907","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	2
Details	Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"UniProtKB","id":"P52907","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	1
Details	Modified residue: {"description":"N-acetylalanine","evidences":[{"source":"UniProtKB","id":"Q13561","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	1
Details	Modified residue: {"description":"Phosphotyrosine","evidences":[{"source":"UniProtKB","id":"Q13561","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---