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PDB: 31 件

7KGQ
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BU of 7kgq by Molmil
Crystal Structure of HLA-A*0201in complex with SARS-CoV-2 N222-230
分子名称: 1,2-ETHANEDIOL, Beta-2-microglobulin, CADMIUM ION, ...
著者Szeto, C, Chatzileontiadou, D.S.M, Riboldi-Tunnicliffe, A, Gras, S.
登録日2020-10-18
公開日2021-01-20
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.34 Å)
主引用文献The presentation of SARS-CoV-2 peptides by the common HLA-A * 02:01 molecule.
Iscience, 24, 2021
7KGP
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BU of 7kgp by Molmil
Crystal Structure of HLA-A*0201 in complex with SARS-CoV-2 N316-324
分子名称: ACETATE ION, Beta-2-microglobulin, CADMIUM ION, ...
著者Szeto, C, Chatzileontiadou, D.S.M, Riboldi-Tunnicliffe, A, Gras, S.
登録日2020-10-18
公開日2021-01-20
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.396 Å)
主引用文献The presentation of SARS-CoV-2 peptides by the common HLA-A * 02:01 molecule.
Iscience, 24, 2021
7QPJ
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BU of 7qpj by Molmil
Crystal structure of engineered TCR (756) complexed to HLA-A*02:01 presenting MAGE-A10 9-mer peptide
分子名称: Beta-2-microglobulin, GLYCEROL, MHC class I antigen, ...
著者Simister, P.C, Border, E.C, Vieira, J.F, Pumphrey, N.J.
登録日2022-01-04
公開日2022-08-03
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.54 Å)
主引用文献Structural insights into engineering a T-cell receptor targeting MAGE-A10 with higher affinity and specificity for cancer immunotherapy.
J Immunother Cancer, 10, 2022
7KGR
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BU of 7kgr by Molmil
Crystal Structure of HLA-A*0201in complex with SARS-CoV-2 N159-167
分子名称: Beta-2-microglobulin, MHC class I antigen, Nucleoprotein
著者Szeto, C, Chatzileontiadou, D.S.M, Riboldi-Tunnicliffe, A, Gras, S.
登録日2020-10-18
公開日2021-01-20
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献The presentation of SARS-CoV-2 peptides by the common HLA-A * 02:01 molecule.
Iscience, 24, 2021
7KGS
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BU of 7kgs by Molmil
Crystal Structure of HLA-A*0201 in complex with SARS-CoV-2 N138-146
分子名称: ACETATE ION, Beta-2-microglobulin, CADMIUM ION, ...
著者Szeto, C, Chatzileontiadou, D.S.M, Riboldi-Tunnicliffe, A, Gras, S.
登録日2020-10-18
公開日2021-01-20
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.58 Å)
主引用文献The presentation of SARS-CoV-2 peptides by the common HLA-A*02:01 molecule.
Iscience, 24, 2021
7MJ7
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BU of 7mj7 by Molmil
HLA-A*02:01 bound to Neuroblastoma Derived IGFBPL1 peptide
分子名称: Beta-2-microglobulin, GLYCEROL, Insulin-like growth factor-binding protein-like 1 peptide, ...
著者Toor, J.S, Tripathi, S.M, Truong, H.V, Yarmarkovich, M, Maris, J.M, Sgourakis, N.G.
登録日2021-04-19
公開日2021-08-18
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Cross-HLA targeting of intracellular oncoproteins with peptide-centric CARs.
Nature, 599, 2021
7T5M
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BU of 7t5m by Molmil
Structure of HLA-A*02:01-FLPTPEELGLLGPPRPQVLA complex
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Beta-2-microglobulin, Interleukin-27 receptor subunit alpha, ...
著者Gras, S.
登録日2021-12-12
公開日2022-12-14
最終更新日2024-01-03
実験手法X-RAY DIFFRACTION (1.67 Å)
主引用文献Cutting Edge: Unconventional CD8 + T Cell Recognition of a Naturally Occurring HLA-A*02:01-Restricted 20mer Epitope.
J Immunol., 208, 2022
7MJ9
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BU of 7mj9 by Molmil
HLA-A*02:01 bound to Neuroblastoma Derived mutant IGFBPL1 peptide
分子名称: Beta-2-microglobulin, Insulin-like growth factor-binding protein-like 1 altered peptide, MHC class I antigen
著者Toor, J.S, Tripathi, S.M, Truong, H.V, Yarmarkovich, M, Maris, J.M, Sgourakis, N.G.
登録日2021-04-19
公開日2021-08-18
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Cross-HLA targeting of intracellular oncoproteins with peptide-centric CARs.
Nature, 599, 2021
7MJ8
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BU of 7mj8 by Molmil
HLA-A*02:01 bound to Neuroblastoma Derived IGFBPL1 peptide
分子名称: Beta-2-microglobulin, GLYCEROL, Insulin-like growth factor-binding protein-like 1 peptide, ...
著者Toor, J.S, Tripathi, S.M, Truong, H.V, Yarmarkovich, M, Maris, J.M, Sgourakis, N.G.
登録日2021-04-19
公開日2021-08-18
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.79 Å)
主引用文献Cross-HLA targeting of intracellular oncoproteins with peptide-centric CARs.
Nature, 599, 2021
7PDW
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BU of 7pdw by Molmil
Crystal structure of parent TCR (728) complexed to HLA-A*02:01 presenting MAGE-A10 9-mer peptide
分子名称: Beta-2-microglobulin, GLYCEROL, MHC class I antigen, ...
著者Simister, P.C, Border, E.C, Vieira, J.F, Pumphrey, N.J.
登録日2021-08-09
公開日2022-08-03
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.82 Å)
主引用文献Structural insights into engineering a T-cell receptor targeting MAGE-A10 with higher affinity and specificity for cancer immunotherapy.
J Immunother Cancer, 10, 2022
7SA2
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BU of 7sa2 by Molmil
SARS-CoV-2 spike-derived peptide S1060-1068 (VVFLHVTYV) presented by HLA-A*02:01
分子名称: Beta-2-microglobulin, CADMIUM ION, MHC class I antigen, ...
著者Szeto, C, Gras, S.
登録日2021-09-21
公開日2022-09-21
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献SARS-CoV-2 spike-derived peptide S1060-1068 (VVFLHVTYV) presented by HLA-A*02:01
To Be Published
7SIS
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BU of 7sis by Molmil
SARS-CoV-2 Spike-derived peptide S976-984 (VLNDILSRL) presented by HLA-A*02:01
分子名称: ACETATE ION, Beta-2-microglobulin, CADMIUM ION, ...
著者Szeto, C, Gras, S.
登録日2021-10-14
公開日2022-11-23
最終更新日2024-05-15
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献The impact of SARS-CoV-2 spike mutation on peptide presentation is HLA allomorph-specific
Curr Res Struct Biol, 2024
7KGT
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BU of 7kgt by Molmil
Crystal Structure of HLA-A*0201 in complex with SARS-CoV-2 N226-234
分子名称: ACETATE ION, Beta-2-microglobulin, CADMIUM ION, ...
著者Szeto, C, Chatzileontiadou, D.S.M, Riboldi-Tunnicliffe, A, Gras, S.
登録日2020-10-18
公開日2021-01-20
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献The presentation of SARS-CoV-2 peptides by the common HLA-A*02:01 molecule.
Iscience, 24, 2021
7MJ6
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BU of 7mj6 by Molmil
HLA-A*02:01 bound to Neuroblastoma Derived IGFBPL1 peptide
分子名称: Beta-2-microglobulin, GLYCEROL, Insulin-like growth factor-binding protein-like 1 peptide, ...
著者Toor, J.S, Tripathi, S.M, Truong, H.V, Yarmarkovich, M, Maris, J.M, Sgourakis, N.G.
登録日2021-04-19
公開日2021-08-18
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Cross-HLA targeting of intracellular oncoproteins with peptide-centric CARs.
Nature, 599, 2021
7PBC
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BU of 7pbc by Molmil
Crystal structure of engineered TCR (796) complexed to HLA-A*02:01 presenting MAGE-A10 9-mer peptide
分子名称: Beta-2-microglobulin, CHLORIDE ION, GLYCEROL, ...
著者Simister, P.C, Border, E.C, Vieira, J.F, Pumphrey, N.J.
登録日2021-08-02
公開日2022-08-03
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.04 Å)
主引用文献Structural insights into engineering a T-cell receptor targeting MAGE-A10 with higher affinity and specificity for cancer immunotherapy.
J Immunother Cancer, 10, 2022
7KGO
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BU of 7kgo by Molmil
Crystal Structure of HLA-A*0201in complex with SARS-CoV-2 N351-359
分子名称: Beta-2-microglobulin, CADMIUM ION, CHLORIDE ION, ...
著者Szeto, C, Chatzileontiadou, D.S.M, Riboldi-Tunnicliffe, A, Gras, S.
登録日2020-10-18
公開日2021-01-20
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献The presentation of SARS-CoV-2 peptides by the common HLA-A * 02:01 molecule.
Iscience, 24, 2021
7N6D
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BU of 7n6d by Molmil
HLA peptide complex
分子名称: 1,2-ETHANEDIOL, Beta-2-microglobulin, MHC class I antigen, ...
著者Chaurasia, P, Petersen, J, Rossjohn, J.
登録日2021-06-08
公開日2021-07-28
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural basis of biased T cell receptor recognition of an immunodominant HLA-A2 epitope of the SARS-CoV-2 spike protein.
J.Biol.Chem., 297, 2021
7M8S
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BU of 7m8s by Molmil
Crystal Structure of HLA-A*02:01 in complex with KLNDLCFTNV, an 10-mer epitope from SARS-CoV-2 Spike (S386-395)
分子名称: Beta-2-microglobulin, GLYCEROL, HLA class I histocompatibility antigen, ...
著者Gras, S, Nguyen, A.T, Szeto, C.
登録日2021-03-30
公開日2021-06-23
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献SARS-CoV-2 Spike-Derived Peptides Presented by HLA Molecules
Biophysica, 1, 2021
6VR1
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BU of 6vr1 by Molmil
Complex of HLA-A2, a class I MHC, with a p53 peptide
分子名称: Beta-2-microglobulin, Cellular tumor antigen p53 peptide, MHC class I antigen
著者Wu, D, Pierce, B.G, Gallagher, D.T, Mariuzza, R.A.
登録日2020-02-06
公開日2020-06-10
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.37 Å)
主引用文献Structural basis for oligoclonal T cell recognition of a shared p53 cancer neoantigen.
Nat Commun, 11, 2020
6VR5
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BU of 6vr5 by Molmil
Complex of HLA-A2, a class I MHC, with a p53 peptide
分子名称: Beta-2-microglobulin, Cellular tumor antigen p53 peptide, MHC class I antigen
著者Wu, D, Gallagher, D.T, Pierce, B.G, Mariuzza, R.A.
登録日2020-02-06
公開日2020-06-17
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.38 Å)
主引用文献Structural basis for oligoclonal T cell recognition of a shared p53 cancer neoantigen.
Nat Commun, 11, 2020
6VRN
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BU of 6vrn by Molmil
T cell receptor-p53-HLA-A2 complex
分子名称: Beta-2-microglobulin, Cellular tumor antigen p53 peptide, MHC class I antigen, ...
著者Wu, D, Gallagher, D.T, Gowthaman, R, Pierce, B.G, Mariuzza, R.A.
登録日2020-02-08
公開日2020-06-17
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.46 Å)
主引用文献Structural basis for oligoclonal T cell recognition of a shared p53 cancer neoantigen.
Nat Commun, 11, 2020
7RE7
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BU of 7re7 by Molmil
TCR mimic antibody (Fab fragment) in complex with AFP/HLA-A*02
分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Beta-2-microglobulin, FORMIC ACID, ...
著者Dasgupta, M, Baker, B.M.
登録日2021-07-12
公開日2022-07-27
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.547 Å)
主引用文献Validation and promise of a TCR mimic antibody for cancer immunotherapy of hepatocellular carcinoma.
Sci Rep, 12, 2022
8GON
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BU of 8gon by Molmil
SARS-CoV-2 specific private TCR RLQ7 in complex with RLQ-T1006I-HLA-A2
分子名称: Beta-2-microglobulin, MHC class I antigen, SARS-CoV-2 specific private TCR RLQ7 alpha, ...
著者Wu, D, Mariuzza, R.A.
登録日2022-08-25
公開日2023-03-01
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.601 Å)
主引用文献Structural insights into protection against a SARS-CoV-2 spike variant by T cell receptor (TCR) diversity.
J.Biol.Chem., 299, 2023
6VRM
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BU of 6vrm by Molmil
T cell receptor-p53-HLA-A2 complex
分子名称: Beta-2-microglobulin, Cellular tumor antigen p53 peptide, MHC class I antigen, ...
著者Wu, D, Gallagher, D.T, Gowthaman, R, Pierce, B.G, Mariuzza, R.A.
登録日2020-02-08
公開日2020-06-17
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.61 Å)
主引用文献Structural basis for oligoclonal T cell recognition of a shared p53 cancer neoantigen.
Nat Commun, 11, 2020
7BBG
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BU of 7bbg by Molmil
CRYSTAL STRUCTURE OF HLA-A2-WT1-RMF AND FAB 11D06
分子名称: Beta-2-microglobulin, Heavy chain of Fab fragment 11D06, Light chain of Fab fragment 11D06, ...
著者Bujotzek, A, Georges, G, Hanisch, L.J, Klein, C, Benz, J.
登録日2020-12-17
公開日2021-10-27
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (2.64 Å)
主引用文献Targeting intracellular WT1 in AML with a novel RMF-peptide-MHC-specific T-cell bispecific antibody.
Blood, 138, 2021

 

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件を2024-07-31に公開中

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