6VR5

Complex of HLA-A2, a class I MHC, with a p53 peptide

Summary for 6VR5

• Entry DOI: 10.2210/pdb6vr5/pdb
• Related: 6vqo 6vr1
• Descriptor: MHC class I antigen, Beta-2-microglobulin, Cellular tumor antigen p53 peptide, ... (4 entities in total)
• Functional Keywords: tcr complex, mhc, hla, adoptive cell therapy, immune system
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 6
• Total formula weight: 93812.29

Authors

Wu, D.,Gallagher, D.T.,Pierce, B.G.,Mariuzza, R.A. (deposition date: 2020-02-06, release date: 2020-06-17, Last modification date: 2023-10-11)

• Primary citation: Wu, D.,Gallagher, D.T.,Gowthaman, R.,Pierce, B.G.,Mariuzza, R.A.; Structural basis for oligoclonal T cell recognition of a shared p53 cancer neoantigen.; Nat Commun, 11:2908-2908, 2020; PubMed: 32518267; DOI: 10.1038/s41467-020-16755-y

Experimental method

X-RAY DIFFRACTION (2.38 Å)