7RE7

TCR mimic antibody (Fab fragment) in complex with AFP/HLA-A*02

Summary for 7RE7

• Entry DOI: 10.2210/pdb7re7/pdb
• Descriptor: Fab heavy chain, TRIETHYLENE GLYCOL, PENTAETHYLENE GLYCOL, ... (13 entities in total)
• Functional Keywords: tcr mimic antibody (fab fragment), class i major histocompatibility complex (hla-a*02), alpha fetoprotein peptide., immune system
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 10
• Total formula weight: 190966.27

Authors

Dasgupta, M.,Baker, B.M. (deposition date: 2021-07-12, release date: 2022-07-27, Last modification date: 2023-10-18)

• Primary citation: Liu, C.,Liu, H.,Dasgupta, M.,Hellman, L.M.,Zhang, X.,Qu, K.,Xue, H.,Wang, Y.,Fan, F.,Chang, Q.,Yu, D.,Ge, L.,Zhang, Y.,Cui, Z.,Zhang, P.,Heller, B.,Zhang, H.,Shi, B.,Baker, B.M.,Liu, C.; Validation and promise of a TCR mimic antibody for cancer immunotherapy of hepatocellular carcinoma.; Sci Rep, 12:12068-12068, 2022; PubMed: 35840635; DOI: 10.1038/s41598-022-15946-5

Experimental method

X-RAY DIFFRACTION (2.547 Å)