4V8D
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![BU of 4v8d by Molmil](/molmil-images/mine/4v8d) | Structure analysis of ribosomal decoding (cognate tRNA-tyr complex). | 分子名称: | 16S ribosomal RNA, 30S RIBOSOMAL PROTEIN S10, 30S RIBOSOMAL PROTEIN S11, ... | 著者 | Jenner, L, Demeshkina, N, Yusupov, M, Yusupova, G. | 登録日 | 2011-12-07 | 公開日 | 2014-07-09 | 最終更新日 | 2019-07-03 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | A new understanding of the decoding principle on the ribosome. Nature, 484, 2012
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4V8G
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![BU of 4v8g by Molmil](/molmil-images/mine/4v8g) | Crystal structure of RMF bound to the 70S ribosome. | 分子名称: | 16S Ribosomal RNA, 23S Ribosomal RNA, 30S Ribosomal Protein S10, ... | 著者 | Polikanov, Y.S, Blaha, G.M, Steitz, T.A. | 登録日 | 2011-12-11 | 公開日 | 2014-07-09 | 最終更新日 | 2014-12-10 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | How hibernation factors RMF, HPF, and YfiA turn off protein synthesis. Science, 336, 2012
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4V7W
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![BU of 4v7w by Molmil](/molmil-images/mine/4v7w) | Structure of the Thermus thermophilus ribosome complexed with chloramphenicol. | 分子名称: | 16S rRNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | 著者 | Bulkley, D.P, Innis, C.A, Blaha, G, Steitz, T.A. | 登録日 | 2010-08-16 | 公開日 | 2014-07-09 | 最終更新日 | 2014-12-10 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Revisiting the structures of several antibiotics bound to the bacterial ribosome. Proc.Natl.Acad.Sci.USA, 107, 2010
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4V7L
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![BU of 4v7l by Molmil](/molmil-images/mine/4v7l) | |
4V9R
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![BU of 4v9r by Molmil](/molmil-images/mine/4v9r) | Crystal structure of antibiotic DITYROMYCIN bound to 70S ribosome | 分子名称: | 16S Ribosomal RNA, 23S Ribosomal RNA, 30S Ribosomal Protein S10, ... | 著者 | Bulkley, D.P, Brandi, L, Polikanov, Y.S, Fabbretti, A, O'Connor, M, Gualerzi, C.O, Steitz, T.A. | 登録日 | 2013-12-05 | 公開日 | 2014-07-09 | 最終更新日 | 2014-12-10 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | The antibiotics dityromycin and GE82832 bind protein S12 and block EF-G-catalyzed translocation. Cell Rep, 6, 2014
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7JQL
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![BU of 7jql by Molmil](/molmil-images/mine/7jql) | Crystal structure of the Thermus thermophilus 70S ribosome in complex with Bac7-001, mRNA, and deacylated P-site tRNA at 3.00A resolution | 分子名称: | 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ... | 著者 | Mardirossian, M, Sola, R, Beckert, B, Valencic, E, Collis, D.W.P, Borisek, J, Armas, F, Di Stasi, A, Buchmann, J, Syroegin, E.A, Polikanov, Y.S, Magistrato, A, Hilpert, K, Wilson, D.N, Scocchi, M. | 登録日 | 2020-08-11 | 公開日 | 2020-08-26 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Peptide Inhibitors of Bacterial Protein Synthesis with Broad Spectrum and SbmA-Independent Bactericidal Activity against Clinical Pathogens. J.Med.Chem., 63, 2020
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6XQE
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![BU of 6xqe by Molmil](/molmil-images/mine/6xqe) | Crystal structure of the Thermus thermophilus 70S ribosome in complex with sarecycline, UAA-mRNA, and deacylated P-site tRNA at 3.00A resolution | 分子名称: | 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ... | 著者 | Batool, Z, Lomakin, I.B, Bunick, C.G, Polikanov, Y.S. | 登録日 | 2020-07-09 | 公開日 | 2020-08-05 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Sarecycline interferes with tRNA accommodation and tethers mRNA to the 70S ribosome. Proc.Natl.Acad.Sci.USA, 117, 2020
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5HAU
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![BU of 5hau by Molmil](/molmil-images/mine/5hau) | Crystal structure of antimicrobial peptide Bac7(1-19) bound to the Thermus thermophilus 70S ribosome | 分子名称: | 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ... | 著者 | Gagnon, M.G, Roy, R.N, Lomakin, I.B, Florin, T, Mankin, A.S, Steitz, T.A. | 登録日 | 2015-12-30 | 公開日 | 2016-04-06 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Structures of proline-rich peptides bound to the ribosome reveal a common mechanism of protein synthesis inhibition. Nucleic Acids Res., 44, 2016
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5J3C
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![BU of 5j3c by Molmil](/molmil-images/mine/5j3c) | |
7JQM
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![BU of 7jqm by Molmil](/molmil-images/mine/7jqm) | Crystal structure of the Thermus thermophilus 70S ribosome in complex with Bac7-002, mRNA, and deacylated P-site tRNA at 3.05A resolution | 分子名称: | 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ... | 著者 | Mardirossian, M, Sola, R, Beckert, B, Valencic, E, Collis, D.W.P, Borisek, J, Armas, F, Di Stasi, A, Buchmann, J, Syroegin, E.A, Polikanov, Y.S, Magistrato, A, Hilpert, K, Wilson, D.N, Scocchi, M. | 登録日 | 2020-08-11 | 公開日 | 2020-08-26 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (3.05 Å) | 主引用文献 | Peptide Inhibitors of Bacterial Protein Synthesis with Broad Spectrum and SbmA-Independent Bactericidal Activity against Clinical Pathogens. J.Med.Chem., 63, 2020
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4WR6
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![BU of 4wr6 by Molmil](/molmil-images/mine/4wr6) | Complex of 70S ribosome with tRNA-Tyr and mRNA with A-A mismatch in the first position in the A-site. | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | 著者 | Rozov, A, Demeshkina, N, Yusupov, M, Yusupova, G. | 登録日 | 2014-10-23 | 公開日 | 2015-06-10 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (3.05 Å) | 主引用文献 | Structural insights into the translational infidelity mechanism. Nat Commun, 6, 2015
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4WT1
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![BU of 4wt1 by Molmil](/molmil-images/mine/4wt1) | Complex of 70S ribosome with tRNA-Phe and mRNA with A-A mismatch in the second position in the A-site | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | 著者 | Rozov, A, Demeshkina, N, Yusupov, M, Yusupova, G. | 登録日 | 2014-10-29 | 公開日 | 2015-06-10 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (3.05 Å) | 主引用文献 | Structural insights into the translational infidelity mechanism. Nat Commun, 6, 2015
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4WRO
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![BU of 4wro by Molmil](/molmil-images/mine/4wro) | Complex of 70S ribosome with tRNA-Phe and mRNA with C-A mismatch in the second position in the A-site | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | 著者 | Rozov, A, Demeshkina, N, Yusupov, M, Yusupova, G. | 登録日 | 2014-10-24 | 公開日 | 2015-06-10 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (3.05 Å) | 主引用文献 | Structural insights into the translational infidelity mechanism. Nat Commun, 6, 2015
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4WRA
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![BU of 4wra by Molmil](/molmil-images/mine/4wra) | Complex of 70S ribosome with tRNA-Tyr and mRNA with A-A mismatch in the first position in the A-site and with antibiotic paromomycin. | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | 著者 | Rozov, A, Demeshkina, N, Yusupov, M, Yusupova, G. | 登録日 | 2014-10-23 | 公開日 | 2015-06-10 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (3.05 Å) | 主引用文献 | Structural insights into the translational infidelity mechanism. Nat Commun, 6, 2015
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5DFE
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![BU of 5dfe by Molmil](/molmil-images/mine/5dfe) | |
6OPE
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![BU of 6ope by Molmil](/molmil-images/mine/6ope) | Crystal structure of tRNA^ Ala(GGC) U32-A38 bound to near-cognate 70S A site | 分子名称: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | 著者 | Nguyen, H.A, Sunita, S, Dunham, C.M. | 登録日 | 2019-04-24 | 公開日 | 2020-06-24 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | Disruption of evolutionarily correlated tRNA elements impairs accurate decoding. Proc.Natl.Acad.Sci.USA, 117, 2020
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4V9S
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![BU of 4v9s by Molmil](/molmil-images/mine/4v9s) | Crystal structure of antibiotic GE82832 bound to 70S ribosome | 分子名称: | 16S Ribosomal RNA, 23S Ribosomal RNA, 30S Ribosomal Protein S10, ... | 著者 | Bulkley, D.P, Brandi, L, Polikanov, Y.S, Fabbretti, A, O'Connor, M, Gualerzi, C.O, Steitz, T.A. | 登録日 | 2013-12-05 | 公開日 | 2014-07-09 | 最終更新日 | 2018-06-27 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | The antibiotics dityromycin and GE82832 bind protein S12 and block EF-G-catalyzed translocation. Cell Rep, 6, 2014
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4V5J
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![BU of 4v5j by Molmil](/molmil-images/mine/4v5j) | Structure of the 70S ribosome bound to Release factor 2 and a substrate analog provides insights into catalysis of peptide release | 分子名称: | 16S Ribosomal RNA, 23S RIBOSOMAL RNA, 30S RIBOSOMAL PROTEIN S10, ... | 著者 | Jin, H, Kelley, A.C, Loakes, D, Ramakrishnan, V. | 登録日 | 2010-03-24 | 公開日 | 2014-07-09 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | Structure of the 70S ribosome bound to release factor 2 and a substrate analog provides insights into catalysis of peptide release. Proc. Natl. Acad. Sci. U.S.A., 107, 2010
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4V6F
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![BU of 4v6f by Molmil](/molmil-images/mine/4v6f) | Elongation complex of the 70S ribosome with three tRNAs and mRNA. | 分子名称: | 16S ribosomal RNA, 23S RIBOSOMAL RNA, 23S RRNA, ... | 著者 | Jenner, L.B, Yusupova, G, Yusupov, M. | 登録日 | 2009-07-09 | 公開日 | 2014-07-09 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | Structural aspects of messenger RNA reading frame maintenance by the ribosome. Nat.Struct.Mol.Biol., 17, 2010
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6ORD
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![BU of 6ord by Molmil](/molmil-images/mine/6ord) | Crystal structure of tRNA^ Ala(GGC) U32-A38 bound to cognate 70S A site | 分子名称: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | 著者 | Nguyen, H.A, Sunita, S, Dunham, C.M. | 登録日 | 2019-04-30 | 公開日 | 2020-06-24 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | Disruption of evolutionarily correlated tRNA elements impairs accurate decoding. Proc.Natl.Acad.Sci.USA, 117, 2020
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4V6A
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![BU of 4v6a by Molmil](/molmil-images/mine/4v6a) | |
4V8N
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![BU of 4v8n by Molmil](/molmil-images/mine/4v8n) | The crystal structure of agmatidine tRNA-Ile2 bound to the 70S ribosome in the A and P site. | 分子名称: | 16S RRNA, 23S RIBOSOMAL RNA, 30S RIBOSOMAL PROTEIN S10, ... | 著者 | Voorhees, R.M, Mandal, D, Neubauer, C, Koehrer, C, RajBhandary, U.L, Ramakrishnan, V. | 登録日 | 2013-02-13 | 公開日 | 2014-07-09 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | The Structural Basis for Specific Decoding of Aua by Isoleucine tRNA on the Ribosome Nat.Struct.Mol.Biol., 20, 2013
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5DOX
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![BU of 5dox by Molmil](/molmil-images/mine/5dox) | Crystal structure of the Thermus thermophilus 70S ribosome in complex with Hygromycin-A at 3.1A resolution | 分子名称: | 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ... | 著者 | Polikanov, Y.S, Starosta, A.L, Juette, M.F, Altman, R.B, Terry, D.S, Lu, W, Burnett, B.J, Dinos, G, Reynolds, K, Blanchard, S.C, Steitz, T.A, Wilson, D.N. | 登録日 | 2015-09-11 | 公開日 | 2015-12-30 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | Distinct tRNA Accommodation Intermediates Observed on the Ribosome with the Antibiotics Hygromycin A and A201A. Mol.Cell, 58, 2015
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4V7Z
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![BU of 4v7z by Molmil](/molmil-images/mine/4v7z) | Structure of the Thermus thermophilus 70S ribosome complexed with telithromycin. | 分子名称: | 16S rRNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | 著者 | Bulkley, D.P, Innis, C.A, Blaha, G, Steitz, T.A. | 登録日 | 2010-08-18 | 公開日 | 2014-07-09 | 最終更新日 | 2021-01-27 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | Revisiting the structures of several antibiotics bound to the bacterial ribosome. Proc.Natl.Acad.Sci.USA, 107, 2010
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4V8H
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![BU of 4v8h by Molmil](/molmil-images/mine/4v8h) | Crystal structure of HPF bound to the 70S ribosome. | 分子名称: | 16S Ribosomal RNA, 23S Ribosomal RNA, 30S Ribosomal Protein S10, ... | 著者 | Polikanov, Y.S, Blaha, G.M, Steitz, T.A. | 登録日 | 2011-12-11 | 公開日 | 2014-07-09 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | How Hibernation Factors RMF, HPF, and YfiA Turn Off Protein Synthesis. Science, 336, 2012
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