6CSX
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6VKT
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3D9B
| Symmetric structure of E. coli AcrB | 分子名称: | Acriflavine resistance protein B, NICKEL (II) ION | 著者 | Veesler, D, Blangy, S, Cambillau, C, Sciara, G. | 登録日 | 2008-05-27 | 公開日 | 2008-07-01 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (3.42 Å) | 主引用文献 | There is a baby in the bath water: AcrB contamination is a major problem in membrane-protein crystallization. Acta Crystallogr.,Sect.F, 64, 2008
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5JMN
| Fusidic acid bound AcrB | 分子名称: | 2-{2-[2-2-(METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, 3,6,9,12,15-PENTAOXAHEPTADECANE, DARPin, ... | 著者 | Oswald, C, Tam, H.K, Pos, K.M. | 登録日 | 2016-04-29 | 公開日 | 2016-12-21 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Transport of lipophilic carboxylates is mediated by transmembrane helix 2 in multidrug transporter AcrB. Nat Commun, 7, 2016
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5YIL
| Hoisting-loop in bacterial multidrug exporter AcrB is a highly flexible hinge that enables the large motion of the subdomains | 分子名称: | Multidrug efflux pump subunit AcrB | 著者 | Zwama, M, Sakurai, K, Hayashi, K, Nakashima, R, Kitagawa, K, Nishino, K, Yamaguchi, A. | 登録日 | 2017-10-05 | 公開日 | 2017-11-15 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Hoisting-Loop in Bacterial Multidrug Exporter AcrB Is a Highly Flexible Hinge That Enables the Large Motion of the Subdomains. Front Microbiol, 8, 2017
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6BAJ
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1IWG
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4U8V
| Coupling of remote alternating-access transport mechanisms for protons and substrates in the multidrug efflux pump AcrB | 分子名称: | (4S,4AS,5AR,12AS)-4,7-BIS(DIMETHYLAMINO)-3,10,12,12A-TETRAHYDROXY-1,11-DIOXO-1,4,4A,5,5A,6,11,12A-OCTAHYDROTETRACENE-2- CARBOXAMIDE, DARPin, DODECYL-BETA-D-MALTOSIDE, ... | 著者 | Pos, K.M. | 登録日 | 2014-08-04 | 公開日 | 2014-10-15 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.298 Å) | 主引用文献 | Coupling of remote alternating-access transport mechanisms for protons and substrates in the multidrug efflux pump AcrB. Elife, 3, 2014
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4U96
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7WLS
| Crystal structure of the multidrug efflux transporter BpeB from Burkholderia pseudomallei | 分子名称: | Efflux pump membrane transporter, TETRAETHYLENE GLYCOL, UNDECYL-MALTOSIDE | 著者 | Kato, T, Hung, L.-W, Yamashita, E, Okada, U, Terwilliger, T.C, Murakami, S. | 登録日 | 2022-01-13 | 公開日 | 2023-07-19 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.94 Å) | 主引用文献 | Crystal structures of multidrug efflux transporters from Burkholderia pseudomallei suggest details of transport mechanism. Proc.Natl.Acad.Sci.USA, 120, 2023
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7WLV
| Crystal Structure of the Multidrug effulx transporter BpeF from Burkholderia pseudomallei. | 分子名称: | DODECYL-BETA-D-MALTOSIDE, Efflux pump membrane transporter | 著者 | Kato, T, Hung, L.-W, Yamashita, E, Okada, U, Terwilliger, T.C, Murakami, S. | 登録日 | 2022-01-13 | 公開日 | 2023-07-19 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Crystal structures of multidrug efflux transporters from Burkholderia pseudomallei suggest details of transport mechanism. Proc.Natl.Acad.Sci.USA, 120, 2023
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2V50
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6NZI
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2W1B
| The structure of the efflux pump AcrB in complex with bile acid | 分子名称: | (3ALPHA,5BETA,12ALPHA)-3,12-DIHYDROXYCHOLAN-24-OIC ACID, ACRIFLAVIN RESISTANCE PROTEIN B | 著者 | Drew, D, Klepsch, M.M, Newstead, S, Flaig, R, De Gier, J.W, Iwata, S, Beis, K. | 登録日 | 2008-10-17 | 公開日 | 2008-12-09 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (3.85 Å) | 主引用文献 | The Structure of the Efflux Pump Acrb in Complex with Bile Acid. Mol.Membr.Biol., 25, 2008
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6IIA
| MexB in complex with LMNG | 分子名称: | Lauryl Maltose Neopentyl Glycol, Multidrug resistance protein MexB | 著者 | Nakashima, R, Sakurai, K, Nakao, K. | 登録日 | 2018-10-04 | 公開日 | 2019-03-27 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.91 Å) | 主引用文献 | Crystal structures of multidrug efflux pump MexB bound with high-molecular-mass compounds. Sci Rep, 9, 2019
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6OWS
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8P1I
| Single particle cryo-EM co-structure of Klebsiella pneumoniae AcrB with the BDM91288 efflux pump inhibitor at 2.97 Angstrom resolution | 分子名称: | 1,2-DIOCTANOYL-SN-GLYCERO-3-[PHOSPHO-RAC-(1-GLYCEROL), 3-chloranyl-2,6-di(piperazin-4-ium-1-yl)quinoline, Efflux pump membrane transporter, ... | 著者 | Boernsen, C, Mueller, R.T, Pos, K.M, Frangakis, A.S. | 登録日 | 2023-05-12 | 公開日 | 2024-01-17 | 最終更新日 | 2024-01-31 | 実験手法 | ELECTRON MICROSCOPY (2.97 Å) | 主引用文献 | Pyridylpiperazine efflux pump inhibitor boosts in vivo antibiotic efficacy against K. pneumoniae. Embo Mol Med, 16, 2024
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4U8Y
| Coupling of remote alternating-access transport mechanisms for protons and substrates in the multidrug efflux pump AcrB | 分子名称: | (4S,4AS,5AR,12AS)-4,7-BIS(DIMETHYLAMINO)-3,10,12,12A-TETRAHYDROXY-1,11-DIOXO-1,4,4A,5,5A,6,11,12A-OCTAHYDROTETRACENE-2- CARBOXAMIDE, DARPin, DODECYL-BETA-D-MALTOSIDE, ... | 著者 | Pos, K.M. | 登録日 | 2014-08-05 | 公開日 | 2014-10-15 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.099 Å) | 主引用文献 | Coupling of remote alternating-access transport mechanisms for protons and substrates in the multidrug efflux pump AcrB. Elife, 3, 2014
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8PX7
| Structure of Bacterial Multidrug Efflux transporter AcrB, solved at wavelength 3.02 A | 分子名称: | Multidrug efflux pump subunit AcrB | 著者 | El Omari, K, Duman, R, Mykhaylyk, V, Orr, C, Qu, F, Beis, K, Wagner, A. | 登録日 | 2023-07-22 | 公開日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (3.4 Å) | 主引用文献 | Experimental phasing opportunities for macromolecular crystallography at very long wavelengths. Commun Chem, 6, 2023
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5T0O
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4U95
| Coupling of remote alternating-access transport mechanisms for protons and substrates in the multidrug efflux pump AcrB | 分子名称: | (4S,4AS,5AR,12AS)-4,7-BIS(DIMETHYLAMINO)-3,10,12,12A-TETRAHYDROXY-1,11-DIOXO-1,4,4A,5,5A,6,11,12A-OCTAHYDROTETRACENE-2- CARBOXAMIDE, DARPin, DODECYL-BETA-D-MALTOSIDE, ... | 著者 | Pos, K.M. | 登録日 | 2014-08-05 | 公開日 | 2014-10-15 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Coupling of remote alternating-access transport mechanisms for protons and substrates in the multidrug efflux pump AcrB eLife, 3, 2014
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3W9I
| Structural basis for the inhibition of bacterial multidrug exporters | 分子名称: | DODECYL-BETA-D-MALTOSIDE, Multidrug resistance protein MexB | 著者 | Sakurai, K, Nakashima, R, Hayashi, K, Yamaguchi, A. | 登録日 | 2013-04-04 | 公開日 | 2013-07-03 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.71 Å) | 主引用文献 | Structural basis for the inhibition of bacterial multidrug exporters Nature, 500, 2013
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3W9J
| Structural basis for the inhibition of bacterial multidrug exporters | 分子名称: | DODECYL-BETA-D-MALTOSIDE, Multidrug resistance protein MexB, [{2-[({[(3R)-1-{8-[(4-tert-butyl-1,3-thiazol-2-yl)carbamoyl]-4-oxo-3-[(E)-2-(1H-tetrazol-5-yl)ethenyl]-4H-pyrido[1,2-a]pyrimidin-2-yl}piperidin-3-yl]oxy}carbonyl)amino]ethyl}(dimethyl)ammonio]acetate | 著者 | Sakurai, K, Nakashima, R, Hayashi, K, Yamaguchi, A. | 登録日 | 2013-04-04 | 公開日 | 2013-07-03 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (3.15 Å) | 主引用文献 | Structural basis for the inhibition of bacterial multidrug exporters Nature, 500, 2013
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3NOG
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3NOC
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