6VKT

Cryo-electron microscopy structures of a gonococcal multidrug efflux pump illuminate a mechanism of erythromycin drug recognition

Summary for 6VKT

• Entry DOI: 10.2210/pdb6vkt/pdb
• EMDB information: 21229
• Descriptor: Efflux pump membrane transporter, PHOSPHATIDYLETHANOLAMINE, ERYTHROMYCIN A (3 entities in total)
• Functional Keywords: efflux, pump, erythromycin, membrane protein
• Biological source: Neisseria gonorrhoeae
• Total number of polymer chains: 3
• Total formula weight: 352548.73

Authors

Lyu, M.,Moseng, M.A. (deposition date: 2020-01-22, release date: 2020-07-01, Last modification date: 2024-03-06)

• Primary citation: Lyu, M.,Moseng, M.A.,Reimche, J.L.,Holley, C.L.,Dhulipala, V.,Su, C.C.,Shafer, W.M.,Yu, E.W.; Cryo-EM Structures of a Gonococcal Multidrug Efflux Pump Illuminate a Mechanism of Drug Recognition and Resistance.; Mbio, 11:-, 2020; PubMed: 32457251; DOI: 10.1128/mBio.00996-20

Experimental method

ELECTRON MICROSCOPY (2.72 Å)