4K7Q
Crystal Structure of AcrB Complexed with Linezolid at 3.5 Resolution
Summary for 4K7Q
Entry DOI | 10.2210/pdb4k7q/pdb |
Descriptor | Acriflavine resistance protein B, N-{[(5S)-3-(3-fluoro-4-morpholin-4-ylphenyl)-2-oxo-1,3-oxazolidin-5-yl]methyl}acetamide (2 entities in total) |
Functional Keywords | inner membrane resistance-nodulation-cell division efflux pump, membrane protein-antibiotic complex, membrane protein/antibiotic |
Biological source | Escherichia coli |
Cellular location | Cell inner membrane ; Multi- pass membrane protein : P31224 |
Total number of polymer chains | 1 |
Total formula weight | 114555.09 |
Authors | Hung, L.W.,Kim, H.B.,Murakami, S.,Gupta, G.,Kim, C.Y.,Terwilliger, T.C. (deposition date: 2013-04-17, release date: 2013-07-03, Last modification date: 2024-02-28) |
Primary citation | Hung, L.W.,Kim, H.B.,Murakami, S.,Gupta, G.,Kim, C.Y.,Terwilliger, T.C. Crystal structure of AcrB complexed with linezolid at 3.5 Angstrom resolution. J.Struct.Funct.Genom., 14:71-75, 2013 Cited by PubMed: 23673416DOI: 10.1007/s10969-013-9154-x PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.5 Å) |
Structure validation
Download full validation report