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PDB: 199 件

4TXW
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Crystal structure of CBM32-4 from the Clostridium perfringens NagH
分子名称: 1,2-ETHANEDIOL, CALCIUM ION, Hyaluronoglucosaminidase
著者Grondin, J.M, Ficko-Blean, E, Boraston, A.B, Smith, S.P.
登録日2014-07-07
公開日2015-12-09
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Solution Structure and Dynamics of Full-length GH84A, a multimodular B-N-acetylglucosaminidase from Clostridium perfringens
To Be Published
2LS6
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Solution NMR Structure of a Non-canonical galactose-binding CBM32 from Clostridium perfringens
分子名称: Hyaluronoglucosaminidase
著者Grondin, J.M, Chitayat, S, Ficko-Blean, E, Boraston, A.B, Smith, S.P.
登録日2012-04-20
公開日2013-05-01
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献An unusual mode of galactose recognition by a family 32 carbohydrate-binding module.
J.Mol.Biol., 426, 2014
7S0P
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BU of 7s0p by Molmil
Crystal structure of Porcine Factor VIII C2 Domain Bound to Phosphatidylserine
分子名称: Coagulation factor VIII, PHOSPHOSERINE
著者Peters, S.C, Childers, K.C, Wo, S.W, Brison, C.M, Swanson, C.D, Spiegel, P.C.
登録日2021-08-30
公開日2021-10-27
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献Stable binding to phosphatidylserine-containing membranes requires conserved arginine residues in tandem C domains of blood coagulation factor VIII.
Front Mol Biosci, 9, 2022
8PFE
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Crystal Structure of an Hexavariant of the b1 Domain of Human Neuropilin-1 in Complex with the KDKPPR Peptide
分子名称: ACETATE ION, LYS-ASP-LYS-PRO-PRO-ARG, Neuropilin-1
著者Jelsch, C, Favier, F, Didierjean, C.
登録日2023-06-15
公開日2023-08-02
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献New Crystal Form of Human Neuropilin-1 b1 Fragment with Six Electrostatic Mutations Complexed with KDKPPR Peptide Ligand.
Molecules, 28, 2023
4XZU
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Crystal Structure of the Human Factor VIII C2 Domain in Complex with Murine 3E6 Inhibitory Antibody
分子名称: 3E6 antibody Fab heavy chain, 3E6 antibody Fab light chain, Coagulation factor VIII, ...
著者Spiegel, P.C, Wuerth, M.E.
登録日2015-02-05
公開日2015-12-09
最終更新日2019-12-04
実験手法X-RAY DIFFRACTION (2.61 Å)
主引用文献Structure of the Human Factor VIII C2 Domain in Complex with the 3E6 Inhibitory Antibody.
Sci Rep, 5, 2015
6OE2
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X-Ray Structure of the C-terminal domain (277-440) of Putative chitobiase from Bacteroides thetaiotaomicron. Northeast Structural Genomics Consortium Target BtR324A. Re-refinement of 3GGL with correct metal Mn replacing Zn. New metal confirmed with PIXE analysis of original sample.
分子名称: Chitobiase, DI(HYDROXYETHYL)ETHER, MANGANESE (II) ION
著者Snell, E.H, Garman, E.F, Lowe, E.D.
登録日2019-03-27
公開日2019-12-25
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献High-Throughput PIXE as an Essential Quantitative Assay for Accurate Metalloprotein Structural Analysis: Development and Application.
J.Am.Chem.Soc., 142, 2020
9EOU
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Crystal Structure of the b1b2 domains from Human Neuropilin-1 in complex with a peptide.
分子名称: Neuropilin-1, Osteopontin
著者Caing-Carlsson, R, Duelli, A, Walse, B.
登録日2024-03-15
公開日2024-06-26
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Identification of an osteopontin-derived peptide that binds neuropilin-1 and activates vascular repair responses and angiogenesis.
Pharmacol Res, 205, 2024
7P5U
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Neuropilin-b1 in a complex with a VEGFB-derived peptide
分子名称: MGC0122, Neuropilin-1
著者Fotinou, C, Rhana, R, Yelland, T.
登録日2021-07-14
公開日2022-07-27
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Neuropilin-b1 in a complex with a VEGFB-derived peptide
To Be Published
3NNG
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BU of 3nng by Molmil
Crystal structure of the F5/8 type C domain of Q5LFR2_BACFN protein from Bacteroides fragilis. Northeast Structural Genomics Consortium Target BfR258E
分子名称: CALCIUM ION, uncharacterized protein
著者Vorobiev, S, Su, M, Dimaio, F, Baker, D, Seetharaman, J, Janjua, J, Xiao, R, Ciccosanti, C, Foote, E.L, Lee, D, Everett, J.K, Nair, R, Acton, T.B, Rost, B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG)
登録日2010-06-23
公開日2010-08-18
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.177 Å)
主引用文献Crystal structure of the F5/8 type C domain of Q5LFR2_BACFN protein from Bacteroides fragilis.
To be Published
5Y4M
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Discoidin domain of human CASPR2
分子名称: 1,2-ETHANEDIOL, human CASPR2 Disc domain
著者Liu, H, Xu, F, Zhang, J, Liang, W.
登録日2017-08-04
公開日2018-08-08
最終更新日2019-02-20
実験手法X-RAY DIFFRACTION (1.31 Å)
主引用文献Structural mapping of hot spots within human CASPR2 discoidin domain for autoantibody recognition.
J. Autoimmun., 96, 2019
7RGA
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Crystal structure of nanoCLAMP3:VHH in complex with MTX
分子名称: METHOTREXATE, SODIUM ION, nano CLostridial Antibody Mimetic Protein 3 VHH
著者Guo, Z, Alexandrov, K.
登録日2021-07-14
公開日2022-05-25
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Design of a methotrexate-controlled chemical dimerization system and its use in bio-electronic devices.
Nat Commun, 12, 2021
5DQ0
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BU of 5dq0 by Molmil
Structure of human neuropilin-2 b1 domain with novel and unique zinc binding site
分子名称: 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHLORIDE ION, ...
著者Tsai, Y.I, Rana, R.R, Zachary, I, Djordjevic, S.
登録日2015-09-14
公開日2016-09-28
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structure of human neuropilin-2 b1 domain with novel and unique zinc binding site
To Be Published
1XPW
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Solution NMR Structure of human protein HSPCO34. Northeast Structural Genomics Target HR1958
分子名称: LOC51668 protein
著者Ramelot, T.A, Xiao, R, Ma, L.C, Acton, T.B, Montelione, G.T, Kennedy, M.A, Northeast Structural Genomics Consortium (NESG)
登録日2004-10-09
公開日2004-11-09
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Improving NMR protein structure quality by Rosetta refinement: a molecular replacement study.
Proteins, 75, 2009
2Z4F
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BU of 2z4f by Molmil
Solution structure of the Discoidin Domain of DDR2
分子名称: Discoidin domain-containing receptor 2
著者Ichikawa, O, Osawa, M, Nishida, N, Goshima, N, Nomura, N, Shimada, I.
登録日2007-06-16
公開日2007-09-04
最終更新日2022-03-16
実験手法SOLUTION NMR
主引用文献Structural basis of the collagen-binding mode of discoidin domain receptor 2
Embo J., 26, 2007
1IQD
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BU of 1iqd by Molmil
Human Factor VIII C2 Domain complexed to human monoclonal BO2C11 Fab.
分子名称: HUMAN FACTOR VIII, HUMAN MONOCLONAL BO2C11 FAB HEAVY CHAIN, HUMAN MONOCLONAL BO2C11 FAB LIGHT CHAIN
著者Spiegel Jr, P.C, Jacquemin, M, Saint-Remy, J.M, Stoddard, B.L, Pratt, K.P.
登録日2001-07-21
公開日2001-08-15
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structure of a factor VIII C2 domain-immunoglobulin G4kappa Fab complex: identification of an inhibitory antibody epitope on the surface of factor VIII.
Blood, 98, 2001
7O1N
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BU of 7o1n by Molmil
Crystal Structure of Human Neuropilin-1 b1 Domain mutant - Y297A
分子名称: Neuropilin-1
著者Djordjevic, S, Chandanani, J, Faleeva, M, Pinotsis, N.
登録日2021-03-29
公開日2022-04-13
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.56 Å)
主引用文献Crystal Structure of Human Neuropilin-1 b1 Domain mutant - Y297A
To Be Published
1TVG
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BU of 1tvg by Molmil
X-ray structure of human PP25 gene product, HSPC034. Northeast Structural Genomics Target HR1958.
分子名称: CALCIUM ION, LOC51668 protein, SAMARIUM (III) ION
著者Kuzin, A.P, Vorobiev, S.M, Lee, I, Acton, T.B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG)
登録日2004-06-29
公開日2004-11-09
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Improving NMR protein structure quality by Rosetta refinement: a molecular replacement study.
Proteins, 75, 2009
6FMF
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BU of 6fmf by Molmil
Neuropilin-1 b1 domain in complex with EG01377; 2.8 Angstrom structure
分子名称: (2~{S})-2-[[3-[[5-[4-(aminomethyl)phenyl]-1-benzofuran-7-yl]sulfonylamino]thiophen-2-yl]carbonylamino]-5-carbamimidamido-pentanoic acid, Neuropilin-1, trifluoroacetic acid
著者Yelland, T, Djordjevic, S, Selwood, D, Zachary, I, Frankel, P.
登録日2018-01-31
公開日2018-10-17
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.811 Å)
主引用文献Small Molecule Neuropilin-1 Antagonists Combine Antiangiogenic and Antitumor Activity with Immune Modulation through Reduction of Transforming Growth Factor Beta (TGF beta ) Production in Regulatory T-Cells.
J. Med. Chem., 61, 2018
1KEX
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BU of 1kex by Molmil
Crystal Structure of the b1 Domain of Human Neuropilin-1
分子名称: Neuropilin-1
著者Lee, C.C, Kreusch, A, McMullan, D, Ng, K, Spraggon, G.
登録日2001-11-18
公開日2003-01-28
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal Structure of the Human Neuropilin-1 b1 Domain
Structure, 11, 2003
6FMC
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Neuropilin1-b1 domain in complex with EG01377, 0.9 Angstrom structure
分子名称: (2~{S})-2-[[3-[[5-[4-(aminomethyl)phenyl]-1-benzofuran-7-yl]sulfonylamino]thiophen-2-yl]carbonylamino]-5-carbamimidamido-pentanoic acid, Neuropilin-1
著者Yelland, T, Djordjevic, S, Fotinou, K, Selwood, D, Zachary, I, Frankel, P.
登録日2018-01-30
公開日2018-10-17
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (0.9 Å)
主引用文献Small Molecule Neuropilin-1 Antagonists Combine Antiangiogenic and Antitumor Activity with Immune Modulation through Reduction of Transforming Growth Factor Beta (TGF beta ) Production in Regulatory T-Cells.
J. Med. Chem., 61, 2018
3BN6
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Crystal Structure of the C2 Domain of Bovine Lactadherin at 1.67 Angstrom Resolution
分子名称: Lactadherin
著者Shao, C, Novakovic, V.A, Head, J.F, Seaton, B.A, Gilbert, G.E.
登録日2007-12-13
公開日2007-12-25
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.67 Å)
主引用文献Crystal structure of lactadherin C2 domain at 1.7A resolution with mutational and computational analyses of its membrane-binding motif.
J.Biol.Chem., 283, 2008
3F2Z
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Crystal structure of the C-terminal domain of a chitobiase (BF3579) from Bacteroides fragilis, Northeast Structural Genomics Consortium Target BfR260B
分子名称: uncharacterized protein BF3579
著者Forouhar, F, Lew, S, Seetharaman, J, Janjua, H, Xiao, R, Foote, E.L, Ciccosanti, C, Lee, D, Nair, R, Everett, J.K, Acton, T.B, Rost, B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG)
登録日2008-10-30
公開日2008-11-18
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献Crystal structure of the C-terminal domain of a chitobiase (BF3579) from Bacteroides fragilis, Northeast Structural Genomics Consortium Target BfR260B
To be Published
5N6W
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Retinoschisin R141H Mutant
分子名称: Retinoschisin
著者Ramsay, E.P, Collins, R.F, Owens, T.W, Siebert, C.A, Jones, R.P.O, Roseman, A, Wang, T, Baldock, C.
登録日2017-02-16
公開日2017-04-12
最終更新日2017-08-30
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献Structural analysis of X-linked retinoschisis mutations reveals distinct classes which differentially effect retinoschisin function
Human Molecular Genetics, 25, 2016
7D2A
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BU of 7d2a by Molmil
CBM32 of AlyQ in complex with 4,5-unsaturated mannuronic acid
分子名称: 4-deoxy-alpha-L-erythro-hex-4-enopyranuronic acid-(1-4)-alpha-L-gulopyranuronic acid, AlyQ, CALCIUM ION, ...
著者Teh, A.H, Sim, P.F.
登録日2020-09-16
公開日2020-12-30
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.57 Å)
主引用文献Structural basis for binding uronic acids by family 32 carbohydrate-binding modules.
Biochem.Biophys.Res.Commun., 533, 2020
7D29
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CBM32 of AlyQ
分子名称: AlyQ, CALCIUM ION
著者Teh, A.H, Sim, P.F.
登録日2020-09-16
公開日2020-12-30
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structural basis for binding uronic acids by family 32 carbohydrate-binding modules.
Biochem.Biophys.Res.Commun., 533, 2020

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