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PDB: 189 件
1WOG
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Crystal Structure of Agmatinase Reveals Structural Conservation and Inhibition Mechanism of the Ureohydrolase Superfamily
分子名称: HEXANE-1,6-DIAMINE, MANGANESE (II) ION, agmatinase
著者Ahn, H.J, Kim, K.H, Lee, J, Ha, J.-Y, Lee, H.H, Kim, D, Yoon, H.-J, Kwon, A.-R, Suh, S.W.
登録日2004-08-18
公開日2004-09-07
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal structure of agmatinase reveals structural conservation and inhibition mechanism of the ureohydrolase superfamily
J.Biol.Chem., 279, 2004
1WOH
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Crystal Structure of Agmatinase Reveals Structural Conservation and Inhibition Mechanism of the Ureohydrolase Superfamily
分子名称: agmatinase
著者Ahn, H.J, Kim, K.H, Lee, J, Ha, J.-Y, Lee, H.H, Kim, D, Yoon, H.-J, Kwon, A.-R, Suh, S.W.
登録日2004-08-18
公開日2004-09-07
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Crystal structure of agmatinase reveals structural conservation and inhibition mechanism of the ureohydrolase superfamily
J.Biol.Chem., 279, 2004
6SS4
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Structure of arginase-2 in complex with the inhibitory human antigen-binding fragment Fab C0021181
分子名称: Arginase-2, mitochondrial, Fab C0021181 heavy chain (IgG1), ...
著者Burschowsky, D, Addyman, A, Fiedler, S, Groves, M, Haynes, S, Seewooruthun, C, Carr, M.
登録日2019-09-06
公開日2020-06-10
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structural and functional characterization of C0021158, a high-affinity monoclonal antibody that inhibits Arginase 2 function via a novel non-competitive mechanism of action.
Mabs, 12
6SS2
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Structure of arginase-2 in complex with the inhibitory human antigen-binding fragment Fab C0021158
分子名称: Arginase-2, mitochondrial, Fab C0021158 heavy chain (IgG1), ...
著者Burschowsky, D, Addyman, A, Fiedler, S, Groves, M, Haynes, S, Seewooruthun, C, Carr, M.
登録日2019-09-06
公開日2020-06-10
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural and functional characterization of C0021158, a high-affinity monoclonal antibody that inhibits Arginase 2 function via a novel non-competitive mechanism of action.
Mabs, 12
6SS6
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BU of 6ss6 by Molmil
Structure of arginase-2 in complex with the inhibitory human antigen-binding fragment Fab C0020187
分子名称: Arginase-2, mitochondrial, Fab C0020187 heavy chain (IgG1), ...
著者Burschowsky, D, Addyman, A, Fiedler, S, Groves, M, Haynes, S, Seewooruthun, C, Carr, M.
登録日2019-09-06
公開日2020-06-10
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (3.25 Å)
主引用文献Extensive sequence and structural evolution of Arginase 2 inhibitory antibodies enabled by an unbiased approach to affinity maturation.
Proc.Natl.Acad.Sci.USA, 117, 2020
6NFP
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BU of 6nfp by Molmil
1.7 Angstrom Resolution Crystal Structure of Arginase from Bacillus subtilis subsp. subtilis str. 168
分子名称: 1,2-ETHANEDIOL, Arginase, CHLORIDE ION, ...
著者Minasov, G, Wawrzak, Z, Evdokimova, E, Grimshaw, S, Kwon, K, Savchenko, A, Satchell, K.J.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2018-12-20
公開日2019-01-02
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献1.7 Angstrom Resolution Crystal Structure of Arginase from Bacillus subtilis subsp. subtilis str. 168
To Be Published
6NBK
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Crystal structure of Arginase from Bacillus cereus
分子名称: Arginase, CALCIUM ION, MANGANESE (II) ION
著者Chang, C, Evdokimova, E, Mcchesney, M, Joachimiak, A, Savchenko, A, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2018-12-07
公開日2018-12-19
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.91 Å)
主引用文献Crystal structure of Arginase from Bacillus cereus
To Be Published
2PHA
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Crystal structure of native, unliganded human arginase at 1.90 resolution
分子名称: Arginase-1, MANGANESE (II) ION
著者Di Costanzo, L, Pique, M.E, Christianson, D.W.
登録日2007-04-10
公開日2007-05-08
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal structure of human arginase I complexed with thiosemicarbazide reveals an unusual thiocarbonyl mu-sulfide ligand in the binuclear manganese cluster.
J.Am.Chem.Soc., 129, 2007
2PLL
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Crystal structure of perdeuterated human arginase I
分子名称: 2(S)-AMINO-6-BORONOHEXANOIC ACID, MANGANESE (II) ION, arginase-1
著者Di Costanzo, L, Moulin, M, Haertlein, M, Meilleur, F, Christianson, D.W.
登録日2007-04-19
公開日2007-08-14
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Expression, purification, assay, and crystal structure of perdeuterated human arginase I
Arch.Biochem.Biophys., 465, 2007
2PHO
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Crystal structure of human arginase I complexed with thiosemicarbazide at 1.95 resolution
分子名称: Arginase-1, HYDRAZINECARBOTHIOAMIDE, MANGANESE (II) ION
著者Di Costanzo, L, Christianson, D.W.
登録日2007-04-11
公開日2007-05-08
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Crystal structure of human arginase I complexed with thiosemicarbazide reveals an unusual thiocarbonyl mu-sulfide ligand in the binuclear manganese cluster.
J.Am.Chem.Soc., 129, 2007
8D27
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BU of 8d27 by Molmil
Arginase Domain of Ornithine Decarboxylase/Arginase from Fusobacterium nucleatum
分子名称: Arginase
著者Chan, A.C, Kolesnikov, M, Murphy, M.E.
登録日2022-05-27
公開日2022-07-06
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Sequence Divergence in the Arginase Domain of Ornithine Decarboxylase/Arginase in Fusobacteriacea Leads to Loss of Function in Oral Associated Species.
Biochemistry, 61, 2022
5YNL
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BU of 5ynl by Molmil
Crystal structure of a cold-adapted arginase from psychrophilic yeast, Glaciozyma antarctica
分子名称: Arginase
著者Yusof, N.Y, Quay, D.H.X, Illias, R.M, Firdaus-Raih, M, Abu-Bakar, F.D, Mahadi, N.M, Murad, A.M.A.
登録日2017-10-24
公開日2018-01-31
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.349 Å)
主引用文献Crystal structure of a cold-adapted arginase from psychrophilic yeast, Glaciozyma antarctica
To Be Published
2CEV
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BU of 2cev by Molmil
ARGINASE FROM BACILLUS CALDEVELOX, NATIVE STRUCTURE AT PH 8.5
分子名称: GUANIDINE, MANGANESE (II) ION, PROTEIN (ARGINASE)
著者Bewley, M.C, Jeffrey, P.D, Patchett, M.L, Kanyo, Z.F, Baker, E.N.
登録日1999-03-10
公開日1999-04-16
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Crystal structures of Bacillus caldovelox arginase in complex with substrate and inhibitors reveal new insights into activation, inhibition and catalysis in the arginase superfamily.
Structure Fold.Des., 7, 1999
8E5M
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Structure of ARG1 complex with pyrrolidine-based non-boronic acid inhibitor 6
分子名称: 1-{[(3S,4S)-3-({4-[2-(4-fluorobenzene-1-sulfonyl)ethyl]piperidin-1-yl}methyl)-4-(3-fluorophenyl)pyrrolidin-1-yl]methyl}cyclopentane-1-carboxylic acid, Arginase-1, MANGANESE (II) ION
著者Palte, R.L, Gathiaka, S.
登録日2022-08-22
公開日2023-03-08
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.84 Å)
主引用文献Discovery of non-boronic acid Arginase 1 inhibitors through virtual screening and biophysical methods.
Bioorg.Med.Chem.Lett., 84, 2023
8E5N
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Structure of ARG1 complex with pyrrolidine-based non-boronic acid inhibitor 10
分子名称: 1-{[(3S,4S)-3-(3-fluorophenyl)-4-{[4-(1,3,4-triethyl-1H-pyrazol-5-yl)piperidin-1-yl]methyl}pyrrolidin-1-yl]methyl}cyclopentane-1-carboxylic acid, Arginase-1, MANGANESE (II) ION
著者Palte, R.L, Gathiaka, S.
登録日2022-08-22
公開日2023-03-08
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.538 Å)
主引用文献Discovery of non-boronic acid Arginase 1 inhibitors through virtual screening and biophysical methods.
Bioorg.Med.Chem.Lett., 84, 2023
5ZEF
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Crystal structure of Entamoeba histolytica Arginase in complex with L- Norvaline at 2.01 A
分子名称: 1,2-ETHANEDIOL, Arginase, GLYCEROL, ...
著者Malik, A, Dalal, V, Ankri, S, Tomar, S.
登録日2018-02-27
公開日2019-06-26
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.01 Å)
主引用文献Structural insights into Entamoeba histolytica arginase and structure-based identification of novel non-amino acid based inhibitors as potential antiamoebic molecules.
Febs J., 286, 2019
2EF4
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BU of 2ef4 by Molmil
Crystal structure of the arginase from thermus thermophilus
分子名称: Arginase
著者Kumarevel, T.S, Karthe, P, Kuramitsu, S, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2007-02-20
公開日2007-04-14
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structure of the arginase from thermus thermophilus
To be Published
2EIV
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BU of 2eiv by Molmil
Crystal Structure of the arginase from Thermus thermophilus
分子名称: Arginase
著者Kumarevel, T.S, Karthe, P, Kuramitsu, S, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2007-03-13
公開日2007-09-18
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.91 Å)
主引用文献Crystal Structure of the arginase from Thermus thermophilus
To be Published
5ZEH
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Crystal structure of Entamoeba histolytica Arginase in complex with L- Ornithine at 2.35 A
分子名称: 1,2-ETHANEDIOL, Arginase, L-ornithine, ...
著者Malik, A, Dalal, V, Ankri, S, Tomar, S.
登録日2018-02-27
公開日2019-06-26
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (2.36 Å)
主引用文献Structural insights into Entamoeba histolytica arginase and structure-based identification of novel non-amino acid based inhibitors as potential antiamoebic molecules.
Febs J., 286, 2019
5ZEE
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BU of 5zee by Molmil
Crystal structure of Entamoeba histolytica Arginase in complex with N(omega)-hydroxy-L-arginine (NOHA) at 1.74 A
分子名称: 1,2-ETHANEDIOL, Arginase, MANGANESE (II) ION, ...
著者Malik, A, Dalal, V, Ankri, S, Tomar, S.
登録日2018-02-27
公開日2019-06-26
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.74 Å)
主引用文献Structural insights into Entamoeba histolytica arginase and structure-based identification of novel non-amino acid based inhibitors as potential antiamoebic molecules.
Febs J., 286, 2019
2EF5
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BU of 2ef5 by Molmil
Crystal structure of the arginase from thermus thermophilus
分子名称: Arginase, GUANIDINE, LYSINE, ...
著者Kumarevel, T.S, Karthe, P, Kuramitsu, S, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2007-02-20
公開日2007-04-14
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structure of the arginase from thermus thermophilus
To be Published
8C0H
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Crystal structure of guanidinase from Nitrospira inopinata
分子名称: NICKEL (II) ION, Putative agmatinase 2, SULFATE ION
著者Puehringer, D.
登録日2022-12-16
公開日2023-12-27
実験手法X-RAY DIFFRACTION (1.58 Å)
主引用文献Growth of complete ammonia oxidizers on guanidine
To Be Published
8IUV
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Crystal structure of Manganese-free N(omega)-hydroxy-L-arginine hydrolase with oxidized Cys86
分子名称: MAGNESIUM ION, MANGANESE (II) ION, N(omega)-hydroxy-L-arginine amidinohydrolase
著者Oda, K, Matoba, Y.
登録日2023-03-25
公開日2024-03-27
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Copper inactivates DcsB by oxidation of the Cys86 to cysteine sulfinic aicd
To Be Published
8IUW
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Crystal structure of Copper-bound N(omega)-hydroxy-L-arginine hydrolase with oxidized Cys86
分子名称: COPPER (I) ION, COPPER (II) ION, MAGNESIUM ION, ...
著者Oda, K, Matoba, Y.
登録日2023-03-25
公開日2024-03-27
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Copper inactivates DcsB by oxidation of the Cys86 to cysteine sulfinic aicd
To Be Published
8IUS
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Crystal structure of Manganese-free N(omega)-hydroxy-L-arginine hydrolase with reduced Cys86
分子名称: MAGNESIUM ION, MANGANESE (II) ION, N(omega)-hydroxy-L-arginine amidinohydrolase
著者Oda, K, Matoba, Y.
登録日2023-03-25
公開日2024-03-27
実験手法X-RAY DIFFRACTION (2.14 Å)
主引用文献Copper inactivates DcsB by oxidation of the Cys86 to cysteine sulfinic aicd
To Be Published

221051

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