5ZEE

Crystal structure of Entamoeba histolytica Arginase in complex with N(omega)-hydroxy-L-arginine (NOHA) at 1.74 A

Summary for 5ZEE

Entry DOI	10.2210/pdb5zee/pdb
Descriptor	Arginase, N-OMEGA-HYDROXY-L-ARGININE, MANGANESE (II) ION, ... (5 entities in total)
Functional Keywords	metalloenzyme, hydrolase-inhibitor complex, hydrolase/inhibitor
Biological source	Entamoeba histolytica
Total number of polymer chains	2
Total formula weight	70502.24
Authors	Malik, A.,Dalal, V.,Ankri, S.,Tomar, S. (deposition date: 2018-02-27, release date: 2019-06-26, Last modification date: 2023-11-22)
Primary citation	Malik, A.,Dalal, V.,Ankri, S.,Tomar, S. Structural insights into Entamoeba histolytica arginase and structure-based identification of novel non-amino acid based inhibitors as potential antiamoebic molecules. Febs J., 286:4135-4155, 2019 Cited by PubMed: 31199070 DOI: 10.1111/febs.14960 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.74 Å)

Structure validation