2PHO
Crystal structure of human arginase I complexed with thiosemicarbazide at 1.95 resolution
Summary for 2PHO
Entry DOI | 10.2210/pdb2pho/pdb |
Related | 2PHA |
Descriptor | Arginase-1, MANGANESE (II) ION, HYDRAZINECARBOTHIOAMIDE, ... (4 entities in total) |
Functional Keywords | thiosemicarbazide, fragment, inhibitor design, hydrolase |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm: P05089 |
Total number of polymer chains | 2 |
Total formula weight | 69870.65 |
Authors | Di Costanzo, L.,Christianson, D.W. (deposition date: 2007-04-11, release date: 2007-05-08, Last modification date: 2023-08-30) |
Primary citation | Di Costanzo, L.,Pique, M.E.,Christianson, D.W. Crystal structure of human arginase I complexed with thiosemicarbazide reveals an unusual thiocarbonyl mu-sulfide ligand in the binuclear manganese cluster. J.Am.Chem.Soc., 129:6388-6389, 2007 Cited by PubMed: 17469833DOI: 10.1021/ja071567j PDB entries with the same primary citation |
Experimental method |
Structure validation
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