5ZEH

Crystal structure of Entamoeba histolytica Arginase in complex with L- Ornithine at 2.35 A

Summary for 5ZEH

Entry DOI	10.2210/pdb5zeh/pdb
Descriptor	Arginase, L-ornithine, MANGANESE (II) ION, ... (5 entities in total)
Functional Keywords	metalloenzyme, inhibition, hydrolase
Biological source	Entamoeba histolytica
Total number of polymer chains	2
Total formula weight	70199.95
Authors	Malik, A.,Dalal, V.,Ankri, S.,Tomar, S. (deposition date: 2018-02-27, release date: 2019-06-26, Last modification date: 2024-03-27)
Primary citation	Malik, A.,Dalal, V.,Ankri, S.,Tomar, S. Structural insights into Entamoeba histolytica arginase and structure-based identification of novel non-amino acid based inhibitors as potential antiamoebic molecules. Febs J., 286:4135-4155, 2019 Cited by PubMed: 31199070 DOI: 10.1111/febs.14960 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.36 Å)

Structure validation