1X59
 
 | | Solution structures of the WHEP-TRS domain of human histidyl-tRNA synthetase | | 分子名称: | Histidyl-tRNA synthetase | | 著者 | Nameki, N, Sasagawa, A, Tomizawa, T, Koshiba, S, Inoue, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2005-05-15 | | 公開日 | 2005-11-15 | | 最終更新日 | 2024-05-29 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structures of the WHEP-TRS domain of human histidyl-tRNA synthetase
To be Published
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1FYJ
 | | SOLUTION STRUCTURE OF MULTI-FUNCTIONAL PEPTIDE MOTIF-1 PRESENT IN HUMAN GLUTAMYL-PROLYL TRNA SYNTHETASE (EPRS). | | 分子名称: | MULTIFUNCTIONAL AMINOACYL-TRNA SYNTHETASE | | 著者 | Jeong, E.-J, Hwang, G.-S, Kim, K.H, Kim, M.J, Kim, S, Kim, K.-S. | | 登録日 | 2000-10-02 | | 公開日 | 2001-03-14 | | 最終更新日 | 2024-05-29 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structural analysis of multifunctional peptide motifs in human bifunctional tRNA synthetase: identification of RNA-binding residues and functional implications for tandem repeats.
Biochemistry, 39, 2000
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1D2D
 | | Hamster EprS second repeated element. NMR, 5 structures | | 分子名称: | TRNA SYNTHETASE | | 著者 | Cahuzac, B, Berthonneau, E, Birlirakis, N, Guittet, E, Mirande, M. | | 登録日 | 1999-09-23 | | 公開日 | 2000-05-24 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | A recurrent RNA-binding domain is appended to eukaryotic aminoacyl-tRNA synthetases.
EMBO J., 19, 2000
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8YOR
 | | Complex of HARSWHEP and a-HARSWHEP Fab | | 分子名称: | Histidine--tRNA ligase, cytoplasmic, a-HARSWHEP Fab-heavy chain, ... | | 著者 | Zhai, L. | | 登録日 | 2024-03-13 | | 公開日 | 2025-02-12 | | 最終更新日 | 2025-04-02 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | A human histidyl-tRNA synthetase splice variant therapeutic targets NRP2 to resolve lung inflammation and fibrosis.
Sci Transl Med, 17, 2025
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2DJV
 | | Solution structures of the WHEP-TRS domain of human methionyl-tRNA synthetase | | 分子名称: | Methionyl-tRNA synthetase | | 著者 | Sato, M, Sasagawa, A, Tochio, N, Koshiba, S, Inoue, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2006-04-05 | | 公開日 | 2006-10-05 | | 最終更新日 | 2024-05-29 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structures of the WHEP-TRS domain of human methionyl-tRNA synthetase
To be Published
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1R1B
 | | EPRS SECOND REPEATED ELEMENT, NMR, MINIMIZED AVERAGE STRUCTURE | | 分子名称: | TRNA SYNTHETASE | | 著者 | Cahuzac, B, Berthonneau, E, Birlirakis, N, Mirande, M, Guittet, E. | | 登録日 | 1998-12-15 | | 公開日 | 1999-12-15 | | 最終更新日 | 2023-12-27 | | 実験手法 | SOLUTION NMR | | 主引用文献 | A recurrent RNA-binding domain is appended to eukaryotic aminoacyl-tRNA synthetases.
EMBO J., 19, 2000
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5UJJ
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4G85
 | | Crystal structure of human HisRS | | 分子名称: | Histidine-tRNA ligase, cytoplasmic | | 著者 | Wei, Z, Wu, J, Zhou, J.J, Yang, X.-L, Zhang, M, Schimmel, P. | | 登録日 | 2012-07-21 | | 公開日 | 2012-09-26 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (3.11 Å) | | 主引用文献 | Internally Deleted Human tRNA Synthetase Suggests Evolutionary Pressure for Repurposing.
Structure, 20, 2012
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4X5O
 | | Human histidine tRNA synthetase | | 分子名称: | Histidine--tRNA ligase, cytoplasmic | | 著者 | Kim, Y.K, Jeon, Y.H. | | 登録日 | 2014-12-05 | | 公開日 | 2015-11-25 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Structural characteristics of human histidyl-tRNA synthetase
Biodesign, 2, 2015
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6O76
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4PHC
 | | Crystal Structure of a human cytosolic histidyl-tRNA synthetase, histidine-bound | | 分子名称: | GLYCEROL, HISTIDINE, Histidine--tRNA ligase, ... | | 著者 | Koh, C.Y, Wetzel, A.B, de van der Schueren, W.J, Hol, W.G.J. | | 登録日 | 2014-05-06 | | 公開日 | 2014-08-27 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.844 Å) | | 主引用文献 | Comparison of histidine recognition in human and trypanosomatid histidyl-tRNA synthetases.
Biochimie, 106, 2014
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5E6M
 | | Crystal structure of human wild type GlyRS bound with tRNAGly | | 分子名称: | GLYCYL-ADENOSINE-5'-PHOSPHATE, Glycine--tRNA ligase, NICKEL (II) ION, ... | | 著者 | Xie, W, Qin, X, Deng, X, Chen, L, Liu, Y. | | 登録日 | 2015-10-10 | | 公開日 | 2016-07-20 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.927 Å) | | 主引用文献 | Crystal Structure of the Wild-Type Human GlyRS Bound with tRNA(Gly) in a Productive Conformation
J.Mol.Biol., 428, 2016
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4KQE
 | | The mutant structure of the human glycyl-tRNA synthetase E71G | | 分子名称: | GLYCEROL, Glycine--tRNA ligase | | 著者 | Qin, X, Hao, Z, Tian, Q, Zhang, Z, Zhou, C, Xie, W. | | 登録日 | 2013-05-15 | | 公開日 | 2014-05-21 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.739 Å) | | 主引用文献 | Large Conformational Changes of Insertion 3 in Human Glycyl-tRNA Synthetase (hGlyRS) during Catalysis
J.Biol.Chem., 291, 2016
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8YP1
 | | Crystal structure of HARS WHEP domain fused with Fc | | 分子名称: | Immunoglobulin heavy constant gamma 1,Histidine--tRNA ligase, cytoplasmic | | 著者 | Geng, Y, Zhai, L. | | 登録日 | 2024-03-15 | | 公開日 | 2025-02-12 | | 最終更新日 | 2025-04-02 | | 実験手法 | X-RAY DIFFRACTION (2.79 Å) | | 主引用文献 | A human histidyl-tRNA synthetase splice variant therapeutic targets NRP2 to resolve lung inflammation and fibrosis.
Sci Transl Med, 17, 2025
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2AZX
 | | Charged and uncharged tRNAs adopt distinct conformations when complexed with human tryptophanyl-tRNA synthetase | | 分子名称: | 72-MER, GLYCEROL, MAGNESIUM ION, ... | | 著者 | Yang, X.L, Otero, F.J, Ewalt, K.L, Liu, J, Swairjo, M.A, Kohrer, C, RajBhandary, U.L, Skene, R.J, McRee, D.E, Schimmel, P. | | 登録日 | 2005-09-12 | | 公開日 | 2006-08-01 | | 最終更新日 | 2024-10-09 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Two conformations of a crystalline human tRNA synthetase-tRNA complex: implications for protein synthesis.
Embo J., 25, 2006
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1R6U
 | | Crystal structure of an active fragment of human tryptophanyl-tRNA synthetase with cytokine activity | | 分子名称: | GLYCEROL, TRYPTOPHANYL-5'AMP, Tryptophanyl-tRNA synthetase | | 著者 | Yang, X.-L, Otero, F.J, Skene, R.J, McRee, D.E, Ribas de Pouplana, L, Schimmel, P. | | 登録日 | 2003-10-16 | | 公開日 | 2004-01-06 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Functional and crystal structure analysis of active site adaptations of a potent anti-angiogenic human tRNA synthetase
Structure, 15, 2007
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1R6T
 | | crystal structure of human tryptophanyl-tRNA synthetase | | 分子名称: | GLYCEROL, TRYPTOPHANYL-5'AMP, Tryptophanyl-tRNA synthetase | | 著者 | Yang, X.-L, Otero, F.J, Skene, R.J, McRee, D.E, Ribas de Pouplana, L, Schimmel, P. | | 登録日 | 2003-10-16 | | 公開日 | 2004-01-06 | | 最終更新日 | 2024-10-09 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Crystal structures that suggest late development of genetic code components for differentiating aromatic side chains
Proc.Natl.Acad.Sci.USA, 100, 2003
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2QUK
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2QUJ
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2QUH
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2QUI
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2LW7
 | | NMR solution structure of human HisRS splice variant | | 分子名称: | Histidine--tRNA ligase, cytoplasmic | | 著者 | Ye, F, Wei, Z, Wu, J, Schimmel, P, Zhang, M. | | 登録日 | 2012-07-24 | | 公開日 | 2013-09-04 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | NMR solution structure of human HisRS splice variant
To be Published
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2ZT5
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2ZT6
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2ZT7
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