1R6U
Crystal structure of an active fragment of human tryptophanyl-tRNA synthetase with cytokine activity
Summary for 1R6U
Entry DOI | 10.2210/pdb1r6u/pdb |
Related | 1N3L 1NTG 1R6T |
Descriptor | Tryptophanyl-tRNA synthetase, TRYPTOPHANYL-5'AMP, GLYCEROL, ... (4 entities in total) |
Functional Keywords | class ic trna synthetase, rossmann fold catalytic domain, anticodon recognition domain, bound trp-amp, ligase |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm: P23381 |
Total number of polymer chains | 2 |
Total formula weight | 101033.81 |
Authors | Yang, X.-L.,Otero, F.J.,Skene, R.J.,McRee, D.E.,Ribas de Pouplana, L.,Schimmel, P. (deposition date: 2003-10-16, release date: 2004-01-06, Last modification date: 2021-10-27) |
Primary citation | Yang, X.-L.,Guo, M.,Kapoor, M.,Ewalt, K.L.,Otero, F.J.,Skene, R.J.,McRee, D.E.,Schimmel, P. Functional and crystal structure analysis of active site adaptations of a potent anti-angiogenic human tRNA synthetase Structure, 15:793-805, 2007 Cited by PubMed: 17637340DOI: 10.1016/j.str.2007.05.009 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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