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4PHC

Crystal Structure of a human cytosolic histidyl-tRNA synthetase, histidine-bound

Summary for 4PHC
Entry DOI10.2210/pdb4phc/pdb
DescriptorHistidine--tRNA ligase, cytoplasmic, HISTIDINE, GLYCEROL, ... (4 entities in total)
Functional Keywordsaminoacyl-trna synthetase, aars, hisrs, human, cytoplasmic, ligase, protein-substrate complex, rossmann-fold, translation, nucleotide binding
Biological sourceHomo sapiens (Human)
Total number of polymer chains4
Total formula weight230950.60
Authors
Koh, C.Y.,Wetzel, A.B.,de van der Schueren, W.J.,Hol, W.G.J. (deposition date: 2014-05-06, release date: 2014-08-27, Last modification date: 2023-12-27)
Primary citationKoh, C.Y.,Wetzel, A.B.,de van der Schueren, W.J.,Hol, W.G.
Comparison of histidine recognition in human and trypanosomatid histidyl-tRNA synthetases.
Biochimie, 106:111-120, 2014
Cited by
PubMed: 25151410
DOI: 10.1016/j.biochi.2014.08.005
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.844 Å)
Structure validation

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