3EFZ
| Crystal Structure of a 14-3-3 protein from cryptosporidium parvum (cgd1_2980) | 分子名称: | 1,2-ETHANEDIOL, 14-3-3 protein | 著者 | Wernimont, A.K, Dong, A, Qiu, W, Lew, J, Wasney, G.A, Vedadi, M, Kozieradzki, I, Zhao, Y, Ren, H, Alam, Z, Lin, Y.H, Sundstrom, M, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Hui, R, Brokx, S, Structural Genomics Consortium (SGC) | 登録日 | 2008-09-10 | 公開日 | 2008-09-23 | 最終更新日 | 2012-02-22 | 実験手法 | X-RAY DIFFRACTION (2.08 Å) | 主引用文献 | Characterization of 14-3-3 proteins from Cryptosporidium parvum. Plos One, 6, 2011
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5EXA
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6TCH
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6TLG
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5EWZ
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5F74
| Crystal structure of ChREBP:14-3-3 complex bound with AMP | 分子名称: | 14-3-3 protein beta/alpha, ADENOSINE MONOPHOSPHATE, Carbohydrate-responsive element-binding protein | 著者 | Jung, H, Uyeda, K. | 登録日 | 2015-12-07 | 公開日 | 2016-03-23 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | Metabolite Regulation of Nuclear Localization of Carbohydrate-response Element-binding Protein (ChREBP): ROLE OF AMP AS AN ALLOSTERIC INHIBITOR. J.Biol.Chem., 291, 2016
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6T5F
| Human 14-3-3 sigma fused to the StARD1 peptide including phosphoserine-195 | 分子名称: | 14-3-3 protein sigma, StARD1 peptide | 著者 | Sluchanko, N.N, Tugaeva, K.V, Titterington, J, Antson, A.A. | 登録日 | 2019-10-16 | 公開日 | 2020-11-18 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.63 Å) | 主引用文献 | Molecular basis for the recognition of steroidogenic acute regulatory protein by the 14-3-3 protein family. Febs J., 287, 2020
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6T80
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5WFX
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6T5H
| Human 14-3-3 sigma fused to the StARD1 peptide including phosphoserine-57 | 分子名称: | 14-3-3 protein sigma,Steroidogenic acute regulatory protein, mitochondrial, IMIDAZOLE, ... | 著者 | Sluchanko, N.N, Tugaeva, K.V, Titterington, J, Antson, A.A. | 登録日 | 2019-10-16 | 公開日 | 2020-11-18 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.04 Å) | 主引用文献 | Molecular basis for the recognition of steroidogenic acute regulatory protein by the 14-3-3 protein family. Febs J., 287, 2020
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5WFU
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5BY9
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5WXN
| Structure of the LKB1 and 14-3-3 complex | 分子名称: | 14-3-3 protein zeta/delta, Serine/threonine-protein kinase STK11 | 著者 | Ding, S, Shi, Z.B. | 登録日 | 2017-01-08 | 公開日 | 2017-04-19 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.93 Å) | 主引用文献 | Structure of the complex of phosphorylated liver kinase B1 and 14-3-3 zeta Acta Crystallogr F Struct Biol Commun, 73, 2017
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4Y3B
| Crystal structure of C-terminal modified Tau peptide-hybrid 201D with 14-3-3sigma | 分子名称: | (2S)-2-(2-methoxyethyl)pyrrolidine, 14-3-3 protein sigma, ARG-THR-PRO-SEP-LEU-PRO-THR-[H][C@@]1(C(C2=CC=CC=C2)C3=CC=CC=C3)CCCN1C | 著者 | Bartel, M, Milroy, L.G, Brunsveld, L, Ottmann, C. | 登録日 | 2015-02-10 | 公開日 | 2015-12-23 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Stabilizer-Guided Inhibition of Protein-Protein Interactions. Angew.Chem.Int.Ed.Engl., 54, 2015
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4Y32
| Crystal structure of C-terminal modified Tau peptide-hybrid 109B with 14-3-3sigma | 分子名称: | (2S)-2-(2-methoxyethyl)pyrrolidine, 14-3-3 protein sigma, ARG-THR-PRO-SEP-LEU-PRO-CNC(C(C)O)C(=O)N1CCCC1CCOC | 著者 | Bartel, M, Milroy, L, Bier, D, Brunsveld, L, Ottmann, C. | 登録日 | 2015-02-10 | 公開日 | 2015-12-23 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Stabilizer-Guided Inhibition of Protein-Protein Interactions. Angew.Chem.Int.Ed.Engl., 54, 2015
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4Y5I
| Crystal structure of C-terminal modified Tau peptide-hybrid 126B with 14-3-3sigma | 分子名称: | 14-3-3 protein sigma, CHLORIDE ION, Microtubule-associated protein tau | 著者 | Leysen, S, Bartel, M, Milroy, L, Brunsveld, L, Ottmann, C. | 登録日 | 2015-02-11 | 公開日 | 2016-01-13 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Stabilizer-Guided Inhibition of Protein-Protein Interactions. Angew.Chem.Int.Ed.Engl., 54, 2015
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5D2D
| Crystal structure of human 14-3-3 zeta in complex with CFTR R-domain peptide pS753-pS768 | 分子名称: | 14-3-3 protein zeta/delta, CHLORIDE ION, Cystic fibrosis transmembrane conductance regulator, ... | 著者 | Stevers, L.M, Leysen, S.F.R, Ottmann, C. | 登録日 | 2015-08-05 | 公開日 | 2016-03-16 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Characterization and small-molecule stabilization of the multisite tandem binding between 14-3-3 and the R domain of CFTR. Proc.Natl.Acad.Sci.USA, 113, 2016
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5D3F
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5XY9
| Structure of the MST4 and 14-3-3 complex | 分子名称: | 14-3-3 protein zeta/delta, 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, GLYCEROL, ... | 著者 | Shi, Z.B, Zhou, Z.C. | 登録日 | 2017-07-06 | 公開日 | 2018-07-11 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.303 Å) | 主引用文献 | Structure of the MST4 and 14-3-3 complex To Be Published
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7PWT
| Crystal structure of 14-3-3 sigma in complex with a C-terminal Estrogen Receptor alpha phosphopeptide, stabilised by pyrrolidone derivative 228 | 分子名称: | (2~{R})-1-(2-hydroxyphenyl)-2-(4-nitrophenyl)-4-oxidanyl-3-(phenylcarbonyl)-2~{H}-pyrrol-5-one, 14-3-3 protein sigma, C-terminus of Estrogen receptor alpha, ... | 著者 | Andrei, S.A, Bosica, F, O'Mahony, G, Ottmann, C. | 登録日 | 2021-10-07 | 公開日 | 2022-12-21 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.312 Å) | 主引用文献 | Designing Selective Drug-like Molecular Glues for the Glucocorticoid Receptor/14-3-3 Protein-Protein Interaction. J.Med.Chem., 65, 2022
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7PWZ
| Crystal structure of 14-3-3 sigma in complex with a C-terminal Estrogen Receptoralpha phosphopeptide, stabilised by Pyrrolidone1 derivative 228 | 分子名称: | 14-3-3 protein sigma, 2-oxidanyl-5-[(2~{R})-4-oxidanyl-5-oxidanylidene-2-(1-oxidanylidene-3~{H}-2-benzofuran-5-yl)-3-(phenylcarbonyl)-2~{H}-pyrrol-1-yl]benzoic acid, C-terminus of Estrogen receptor alpha, ... | 著者 | Andrei, S.A, Bosica, F, O'Mahony, G, Ottmann, C. | 登録日 | 2021-10-07 | 公開日 | 2022-12-21 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Designing Selective Drug-like Molecular Glues for the Glucocorticoid Receptor/14-3-3 Protein-Protein Interaction. J.Med.Chem., 65, 2022
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7QI1
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5D3E
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4ZDR
| Crystal structure of 14-3-3[zeta]-LKB1 fusion protein | 分子名称: | 14-3-3 protein zeta/delta,GGSGGS linker,Serine/threonine-protein kinase STK11, GLYCEROL, PROPANE, ... | 著者 | Ding, S, Shi, Z.B. | 登録日 | 2015-04-18 | 公開日 | 2015-09-09 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.899 Å) | 主引用文献 | Structure of the 14-3-3 zeta-LKB1 fusion protein provides insight into a novel ligand-binding mode of 14-3-3. Acta Crystallogr.,Sect.F, 71, 2015
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4ZQ0
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