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PDB: 1507 件
6QML
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BU of 6qml by Molmil
UCHL3 in complex with synthetic, K27-linked diubiquitin
分子名称: 1,2-ETHANEDIOL, BROMIDE ION, CHLORIDE ION, ...
著者Murachelli, A.G, Sixma, T.K.
登録日2019-02-07
公開日2020-02-26
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献K27-Linked Diubiquitin Inhibits UCHL3 via an Unusual Kinetic Trap.
Cell Chem Biol, 28, 2021
5CVN
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BU of 5cvn by Molmil
WDR48 (2-580):USP46~ubiquitin ternary complex
分子名称: Polyubiquitin-B, Ubiquitin carboxyl-terminal hydrolase 46, WD repeat-containing protein 48, ...
著者Harris, S.F, Yin, J.
登録日2015-07-27
公開日2015-10-07
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3.36 Å)
主引用文献Structural Insights into WD-Repeat 48 Activation of Ubiquitin-Specific Protease 46.
Structure, 23, 2015
5CVO
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BU of 5cvo by Molmil
WDR48:USP46~ubiquitin ternary complex
分子名称: Polyubiquitin-B, Ubiquitin carboxyl-terminal hydrolase 46, WD repeat-containing protein 48, ...
著者Harris, S.F, Yin, J.
登録日2015-07-27
公開日2015-10-07
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3.885 Å)
主引用文献Structural Insights into WD-Repeat 48 Activation of Ubiquitin-Specific Protease 46.
Structure, 23, 2015
5B83
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BU of 5b83 by Molmil
Crystal structure of Optineurin UBAN in complex with linear ubiquitin
分子名称: Optineurin, tetra ubiquitin
著者Ishii, R, Nureki, O.
登録日2016-06-12
公開日2016-09-07
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.694 Å)
主引用文献Linear ubiquitination is involved in the pathogenesis of optineurin-associated amyotrophic lateral sclerosis
Nat Commun, 7, 2016
6R7F
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BU of 6r7f by Molmil
Structural basis of Cullin-2 RING E3 ligase regulation by the COP9 signalosome
分子名称: COP9 signalosome complex subunit 1, COP9 signalosome complex subunit 2, COP9 signalosome complex subunit 3, ...
著者Faull, S.V, Lau, A.M.C, Martens, C, Ahdash, Z, Yebenes, H, Schmidt, C, Beuron, F, Cronin, N.B, Morris, E.P, Politis, A.
登録日2019-03-28
公開日2019-08-28
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (8.2 Å)
主引用文献Structural basis of Cullin 2 RING E3 ligase regulation by the COP9 signalosome.
Nat Commun, 10, 2019
6RPQ
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BU of 6rpq by Molmil
Crystal structure of PhoCDC21-1 intein
分子名称: Ubiquitin-like protein SMT3,1108aa long hypothetical cell division control protein
著者Beyer, H.M, Mikula, K.M, Iwai, H.
登録日2019-05-14
公開日2019-08-14
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.654 Å)
主引用文献Crystal structures of CDC21-1 inteins from hyperthermophilic archaea reveal the selection mechanism for the highly conserved homing endonuclease insertion site.
Extremophiles, 23, 2019
6R7H
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BU of 6r7h by Molmil
Structural basis of Cullin-2 RING E3 ligase regulation by the COP9 signalosome
分子名称: COP9 signalosome complex subunit 1, COP9 signalosome complex subunit 2, COP9 signalosome complex subunit 3, ...
著者Faull, S.V, Lau, A.M.C, Beuron, F, Cronin, N.B, Morris, E.P, Politis, A.
登録日2019-03-28
公開日2019-08-28
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (8.8 Å)
主引用文献Structural basis of Cullin 2 RING E3 ligase regulation by the COP9 signalosome.
Nat Commun, 10, 2019
6R7N
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BU of 6r7n by Molmil
Structural basis of Cullin-2 RING E3 ligase regulation by the COP9 signalosome
分子名称: COP9 signalosome complex subunit 1, COP9 signalosome complex subunit 2, COP9 signalosome complex subunit 3, ...
著者Faull, S.V, Lau, A.M.C, Martens, C, Ahdash, Z, Yebenes, H, Schmidt, C, Beuron, F, Cronin, N.B, Morris, E.P, Politis, A.
登録日2019-03-29
公開日2019-08-28
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (6.5 Å)
主引用文献Structural basis of Cullin 2 RING E3 ligase regulation by the COP9 signalosome.
Nat Commun, 10, 2019
6R7I
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BU of 6r7i by Molmil
Structural basis of Cullin-2 RING E3 ligase regulation by the COP9 signalosome
分子名称: COP9 signalosome complex subunit 1, COP9 signalosome complex subunit 2, COP9 signalosome complex subunit 3, ...
著者Faull, S.F, Lau, A.M.C, Beuron, F, Cronin, N.B, Morris, E.P, Politis, A.
登録日2019-03-28
公開日2019-08-28
最終更新日2019-09-04
実験手法ELECTRON MICROSCOPY (5.9 Å)
主引用文献Structural basis of Cullin 2 RING E3 ligase regulation by the COP9 signalosome.
Nat Commun, 10, 2019
6O82
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BU of 6o82 by Molmil
S. pombe ubiquitin E1 complex with a ubiquitin-AMP mimic
分子名称: 1,2-ETHANEDIOL, 5'-deoxy-5'-(sulfamoylamino)adenosine, MAGNESIUM ION, ...
著者Olsen, S.K, Lima, C.D.
登録日2019-03-08
公開日2019-06-19
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.604 Å)
主引用文献Structural basis for adenylation and thioester bond formation in the ubiquitin E1.
Proc.Natl.Acad.Sci.USA, 116, 2019
6O4A
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BU of 6o4a by Molmil
CRYSTAL STRUCTURE OF SMT FUSION PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FROM BURKHOLDERIA PSEUDOMALLEI COMPLEXED WITH SF355
分子名称: 2-(pyridin-3-ylcarbonylamino)ethyl (2~{S})-1-(phenylmethyl)sulfonylpiperidine-2-carboxylate, CALCIUM ION, Ubiquitin-like protein SMT3,Peptidyl-prolyl cis-trans isomerase
著者Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2019-02-28
公開日2020-02-12
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献CRYSTAL STRUCTURE OF SMT FUSION PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FROM BURKHOLDERIA PSEUDOMALLEI COMPLEXED WITH SF355
to be published
6OAM
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BU of 6oam by Molmil
Crystal Structure of ChlaDUB2 DUB domain
分子名称: Deubiquitinase and deneddylase Dub2, Ubiquitin
著者Hausman, J.M, Das, C.
登録日2019-03-17
公開日2020-04-22
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.503 Å)
主引用文献The Two Deubiquitinating Enzymes fromChlamydia trachomatisHave Distinct Ubiquitin Recognition Properties.
Biochemistry, 59, 2020
6P59
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BU of 6p59 by Molmil
Crystal structure of SIVrcm Vif-CBFbeta-ELOB-ELOC complex
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Core-binding factor subunit beta, Elongin-B, ...
著者Binning, J.M, Chesarino, N.M, Emerman, M, Gross, J.D.
登録日2019-05-29
公開日2019-12-25
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.942214 Å)
主引用文献Structural Basis for a Species-Specific Determinant of an SIV Vif Protein toward Hominid APOBEC3G Antagonism.
Cell Host Microbe, 26, 2019
6PGV
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BU of 6pgv by Molmil
Human Josephin-2 in complex with ubiquitin
分子名称: ETHANAMINE, Josephin-2, Polyubiquitin-B
著者Grasty, K.C, Weeks, S.D, Loll, P.J.
登録日2019-06-24
公開日2019-10-23
最終更新日2019-12-18
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural insights into the activity and regulation of human Josephin-2
J.Struct.Biol., 3, 2019
6Q00
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BU of 6q00 by Molmil
TDP2 UBA Domain Bound to Ubiquitin at 0.85 Angstroms Resolution, Crystal Form 1
分子名称: POTASSIUM ION, Tyrosyl-DNA phosphodiesterase 2, Ubiquitin
著者Schellenberg, M.J, Krahn, J.M, Williams, R.S.
登録日2019-08-01
公開日2020-04-29
最終更新日2020-06-24
実験手法X-RAY DIFFRACTION (0.85 Å)
主引用文献Ubiquitin stimulated reversal of topoisomerase 2 DNA-protein crosslinks by TDP2.
Nucleic Acids Res., 48, 2020
6PZV
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BU of 6pzv by Molmil
Crystal Structure of Bovine DNMT1 RFTS domain in complex with H3K9me3 and Ubiquitin
分子名称: CITRATE ANION, DNA (cytosine-5)-methyltransferase 1, Histone H3.3, ...
著者Ren, W, Song, J.
登録日2019-08-01
公開日2020-07-15
最終更新日2020-08-12
実験手法X-RAY DIFFRACTION (3.01 Å)
主引用文献Direct readout of heterochromatic H3K9me3 regulates DNMT1-mediated maintenance DNA methylation.
Proc.Natl.Acad.Sci.USA, 117, 2020
6Q01
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BU of 6q01 by Molmil
TDP2 UBA Domain Bound to Ubiquitin at 0.85 Angstroms Resolution, Crystal Form 2
分子名称: 1,2-ETHANEDIOL, BENZOIC ACID, MAGNESIUM ION, ...
著者Schellenberg, M.J, Krahn, J.M, Williams, R.S.
登録日2019-08-01
公開日2020-04-29
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (0.851 Å)
主引用文献Ubiquitin stimulated reversal of topoisomerase 2 DNA-protein crosslinks by TDP2.
Nucleic Acids Res., 48, 2020
6OI4
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BU of 6oi4 by Molmil
RPN13 (19-132)-RPN2 (940-952) pY950-Ub complex
分子名称: 1,2-ETHANEDIOL, 26S proteasome non-ATPase regulatory subunit 1, Proteasomal ubiquitin receptor ADRM1, ...
著者Hemmis, C.W, Hill, C.P.
登録日2019-04-08
公開日2019-05-15
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.76 Å)
主引用文献Phosphorylation of Tyr-950 in the proteasome scaffolding protein RPN2 modulates its interaction with the ubiquitin receptor RPN13.
J.Biol.Chem., 294, 2019
6O83
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BU of 6o83 by Molmil
S. pombe ubiquitin E1~ubiquitin-AMP tetrahedral intermediate mimic
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 5'-{[(3-aminopropyl)sulfonyl]amino}-5'-deoxyadenosine, ...
著者Hann, Z.S, Lima, C.D.
登録日2019-03-08
公開日2019-06-19
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.153 Å)
主引用文献Structural basis for adenylation and thioester bond formation in the ubiquitin E1.
Proc.Natl.Acad.Sci.USA, 116, 2019
3I3T
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BU of 3i3t by Molmil
Crystal structure of covalent ubiquitin-USP21 complex
分子名称: ETHANAMINE, Ubiquitin, Ubiquitin carboxyl-terminal hydrolase 21, ...
著者Neculai, D, Avvakumov, G.V, Walker, J.R, Xue, S, Butler-Cole, C, Weigelt, J, Bountra, C, Edwards, A.M, Arrowsmith, C.H, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC)
登録日2009-06-30
公開日2009-07-21
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.59 Å)
主引用文献A strategy for modulation of enzymes in the ubiquitin system.
Science, 339, 2013
3IHP
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BU of 3ihp by Molmil
Covalent Ubiquitin-Usp5 Complex
分子名称: CHLORIDE ION, ETHANAMINE, Ubiquitin, ...
著者Walker, J.R, Avvakumov, G.V, Xue, S, Butler-Cole, C, Weigelt, J, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC)
登録日2009-07-30
公開日2009-12-29
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Covalent Ubiquitin-Usp5 Complex
To be Published
3IFW
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BU of 3ifw by Molmil
Crystal structure of the S18Y variant of ubiquitin carboxy terminal hydrolase L1 bound to ubiquitin vinylmethylester.
分子名称: METHYL 4-AMINOBUTANOATE, Ubiquitin, Ubiquitin carboxyl-terminal hydrolase isozyme L1
著者Das, C, Boudreaux, D, Maiti, T.
登録日2009-07-26
公開日2010-06-16
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Ubiquitin vinyl methyl ester binding orients the misaligned active site of the ubiquitin hydrolase UCHL1 into productive conformation.
Proc.Natl.Acad.Sci.USA, 107, 2010
3JSV
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BU of 3jsv by Molmil
Crystal structure of mouse NEMO CoZi in complex with Lys63-linked di-ubiquitin
分子名称: NF-kappa-B essential modulator, Ubiquitin
著者Yoshikawa, A, Sato, Y, Mimura, H, Yamashita, M, Yamagata, A, Fukai, S.
登録日2009-09-11
公開日2009-10-27
最終更新日2021-11-10
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Crystal structure of the NEMO ubiquitin-binding domain in complex with Lys 63-linked di-ubiquitin
Febs Lett., 583, 2009
3L0W
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BU of 3l0w by Molmil
Structure of split monoubiquitinated PCNA with ubiquitin in position two
分子名称: Monoubiquitinated Proliferating cell nuclear antigen, Proliferating cell nuclear antigen
著者Freudenthal, B.D, Gakhar, L, Ramaswamy, S, Washington, M.T.
登録日2009-12-10
公開日2010-03-23
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structure of monoubiquitinated PCNA and implications for translesion synthesis and DNA polymerase exchange.
Nat.Struct.Mol.Biol., 17, 2010
3L10
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BU of 3l10 by Molmil
Structure of split monoubiquitinated PCNA with ubiquitin in position one
分子名称: Monoubiquitinated Proliferating cell nuclear antigen, Proliferating cell nuclear antigen
著者Freudenthal, B.D, Gakhar, L, Ramaswamy, S, Washington, M.T.
登録日2009-12-10
公開日2010-03-23
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structure of monoubiquitinated PCNA and implications for translesion synthesis and DNA polymerase exchange.
Nat.Struct.Mol.Biol., 17, 2010

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