6Q01
TDP2 UBA Domain Bound to Ubiquitin at 0.85 Angstroms Resolution, Crystal Form 2
Summary for 6Q01
| Entry DOI | 10.2210/pdb6q01/pdb |
| Related | 6Q00 |
| Descriptor | Ubiquitin, Tyrosyl-DNA phosphodiesterase 2, MAGNESIUM ION, ... (7 entities in total) |
| Functional Keywords | tdp2, dna damage response, cell signaling, post-translational modification, topoisomerase 2, signaling protein, signaling protein-hydrolase complex, signaling protein/hydrolase |
| Biological source | Homo sapiens (Human) More |
| Total number of polymer chains | 4 |
| Total formula weight | 27559.00 |
| Authors | Schellenberg, M.J.,Krahn, J.M.,Williams, R.S. (deposition date: 2019-08-01, release date: 2020-04-29, Last modification date: 2024-03-13) |
| Primary citation | Schellenberg, M.J.,Appel, C.D.,Riccio, A.A.,Butler, L.R.,Krahn, J.M.,Liebermann, J.A.,Cortes-Ledesma, F.,Williams, R.S. Ubiquitin stimulated reversal of topoisomerase 2 DNA-protein crosslinks by TDP2. Nucleic Acids Res., 48:6310-6325, 2020 Cited by PubMed: 32356875DOI: 10.1093/nar/gkaa318 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (0.851 Å) |
Structure validation
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