3PHD
 
 | | Crystal structure of human HDAC6 in complex with ubiquitin | | 分子名称: | Histone deacetylase 6, Polyubiquitin, ZINC ION | | 著者 | Dong, A, Qui, W, Ravichandran, M, Schuetz, A, Loppnau, P, Li, F, Mackenzie, F, Kozieradzki, I, Ouyang, H, Structural Genomics Consortium (SGC) | | 登録日 | 2010-11-03 | | 公開日 | 2011-02-23 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Protein Aggregates Are Recruited to Aggresome by Histone Deacetylase 6 via Unanchored Ubiquitin C Termini.
J.Biol.Chem., 287, 2012
|
|
3PRM
 | | Structural analysis of a viral OTU domain protease from the Crimean-Congo Hemorrhagic Fever virus in complex with human ubiquitin | | 分子名称: | Polyubiquitin-B (Fragment), RNA-directed RNA polymerase L | | 著者 | Capodagli, G.C, McKercher, M.A, Baker, E.A, Masters, E.M, Brunzelle, J.S, Pegan, S.D. | | 登録日 | 2010-11-30 | | 公開日 | 2011-01-26 | | 最終更新日 | 2023-02-22 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structural analysis of a viral ovarian tumor domain protease from the crimean-congo hemorrhagic Fever virus in complex with covalently bonded ubiquitin.
J.Virol., 85, 2011
|
|
3NHE
 | |
3OLM
 | | Structure and Function of a Ubiquitin Binding Site within the Catalytic Domain of a HECT Ubiquitin Ligase | | 分子名称: | E3 ubiquitin-protein ligase RSP5, Ubiquitin | | 著者 | Kim, H.C, Steffen, A, Chen, J, Huibregtse, J.M. | | 登録日 | 2010-08-26 | | 公開日 | 2011-03-23 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.495 Å) | | 主引用文献 | Structure and function of a HECT domain ubiquitin-binding site.
Embo Rep., 12, 2011
|
|
3Q3F
 | | Engineering Domain-Swapped Binding Interfaces by Mutually Exclusive Folding: Insertion of Ubiquitin into position 103 of Barnase | | 分子名称: | Ribonuclease/Ubiquitin chimeric protein, SULFATE ION | | 著者 | Ha, J.-H, Karchin, J.M, Walker-Kopp, N, Huang, L.-S, Berry, E.A, Loh, S.N. | | 登録日 | 2010-12-21 | | 公開日 | 2012-01-25 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.169 Å) | | 主引用文献 | Engineering domain-swapped binding interfaces by mutually exclusive folding.
J.Mol.Biol., 416, 2012
|
|
3PSE
 | | Structure of a viral OTU domain protease bound to interferon-stimulated gene 15 (ISG15) | | 分子名称: | 1.7.6 3-bromanylpropan-1-amine, GLYCEROL, RNA polymerase, ... | | 著者 | Bacik, J.P, James, T.W, Frias-Staheli, N, Garcia-Sastre, A, Mark, B.L. | | 登録日 | 2010-12-01 | | 公開日 | 2011-01-19 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structural basis for the removal of ubiquitin and interferon-stimulated gene 15 by a viral ovarian tumor domain-containing protease.
Proc.Natl.Acad.Sci.USA, 108, 2011
|
|
3PT2
 | | Structure of a viral OTU domain protease bound to Ubiquitin | | 分子名称: | 1.7.6 3-bromanylpropan-1-amine, ACETATE ION, RNA polymerase, ... | | 著者 | James, T.W, Bacik, J.P, Frias-Staheli, N, Garcia-Sastre, A, Mark, B.L. | | 登録日 | 2010-12-02 | | 公開日 | 2011-01-19 | | 最終更新日 | 2023-05-31 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structural basis for the removal of ubiquitin and interferon-stimulated gene 15 by a viral ovarian tumor domain-containing protease.
Proc.Natl.Acad.Sci.USA, 108, 2011
|
|
3PHW
 | | OTU Domain of Crimean Congo Hemorrhagic Fever Virus in complex with Ubiquitin | | 分子名称: | ETHANAMINE, RNA-directed RNA polymerase L, Ubiquitin-40S ribosomal protein S27a | | 著者 | Akutsu, M, Ye, Y, Virdee, S, Komander, D. | | 登録日 | 2010-11-04 | | 公開日 | 2011-02-02 | | 最終更新日 | 2014-08-06 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Molecular basis for ubiquitin and ISG15 cross-reactivity in viral ovarian tumor domains.
Proc.Natl.Acad.Sci.USA, 108, 2011
|
|
3PLU
 | | Structure of Hub-1 protein in complex with Snu66 peptide (HINDI) | | 分子名称: | 66 kDa U4/U6.U5 small nuclear ribonucleoprotein component, Ubiquitin-like modifier HUB1 | | 著者 | Mishra, S.K, Ammon, T, Popowicz, G.M, Krajewski, M, Nagel, R.J, Ares, M, Holak, T.A, Jentsch, S. | | 登録日 | 2010-11-15 | | 公開日 | 2011-06-01 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | Role of the ubiquitin-like protein Hub1 in splice-site usage and alternative splicing.
Nature, 474, 2011
|
|
3PLV
 | | Structure of Hub-1 protein in complex with Snu66 peptide (HINDII) | | 分子名称: | 66 kDa U4/U6.U5 small nuclear ribonucleoprotein component, Ubiquitin-like modifier HUB1 | | 著者 | Mishra, S.K, Ammon, T, Popowicz, G.M, Krajewski, M, Nagel, R.J, Ares, M, Holak, T.A, Jentsch, S. | | 登録日 | 2010-11-15 | | 公開日 | 2011-06-01 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Role of the ubiquitin-like protein Hub1 in splice-site usage and alternative splicing.
Nature, 474, 2011
|
|
3N3K
 | | The catalytic domain of USP8 in complex with a USP8 specific inhibitor | | 分子名称: | Ubiquitin, Ubiquitin carboxyl-terminal hydrolase 8, ZINC ION | | 著者 | Walker, J.R, Avvakumov, G.V, Xue, S, Li, Y, Allali-Hassani, A, Lam, R, Ernst, A, Sidhu, S, Weigelt, J, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium, Structural Genomics Consortium (SGC) | | 登録日 | 2010-05-20 | | 公開日 | 2010-06-23 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | A strategy for modulation of enzymes in the ubiquitin system.
Science, 339, 2013
|
|
3PRP
 | | Structural analysis of a viral OTU domain protease from the Crimean-Congo Hemorrhagic Fever virus in complex with human ubiquitin | | 分子名称: | Polyubiquitin-B (Fragment), RNA-directed RNA polymerase L | | 著者 | Capodagli, G.C, McKercher, M.A, Baker, E.A, Masters, E.M, Brunzelle, J.S, Pegan, S.D. | | 登録日 | 2010-11-30 | | 公開日 | 2011-01-26 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.699 Å) | | 主引用文献 | Structural analysis of a viral ovarian tumor domain protease from the crimean-congo hemorrhagic Fever virus in complex with covalently bonded ubiquitin.
J.Virol., 85, 2011
|
|
5BZ0
 | |
5C7M
 | | CRYSTAL STRUCTURE OF E3 LIGASE ITCH WITH A UB VARIANT | | 分子名称: | E3 ubiquitin-protein ligase Itchy homolog, Polyubiquitin-C | | 著者 | Walker, J.R, Hu, J, Dong, A, Wernimont, A, Zhang, W, Sidhu, S, Bountra, C, Edwards, A.M, Arrowsmith, C.H, Tong, Y, Structural Genomics Consortium (SGC) | | 登録日 | 2015-06-24 | | 公開日 | 2016-03-16 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (3.03 Å) | | 主引用文献 | System-Wide Modulation of HECT E3 Ligases with Selective Ubiquitin Variant Probes.
Mol.Cell, 62, 2016
|
|
5C23
 | | Parkin (S65DUblR0RBR) | | 分子名称: | CHLORIDE ION, E3 ubiquitin-protein ligase parkin, GLYCEROL, ... | | 著者 | Kumar, A, Aguirre, J.D, Condos, T.E.C, Martinez-Torres, R.J, Chaugule, V.K, Toth, R, Sundaramoorthy, R, Mercier, P, Knebel, A, Spratt, D.E, Barber, K.R, Shaw, G.S, Walden, H. | | 登録日 | 2015-06-15 | | 公開日 | 2015-07-29 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.37 Å) | | 主引用文献 | Disruption of the autoinhibited state primes the E3 ligase parkin for activation and catalysis.
Embo J., 34, 2015
|
|
5CHV
 | | Crystal structure of USP18-ISG15 complex | | 分子名称: | CHLORIDE ION, SULFATE ION, Ubiquitin-like protein ISG15, ... | | 著者 | Fritz, G, Basters, A. | | 登録日 | 2015-07-10 | | 公開日 | 2016-09-28 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (3.005 Å) | | 主引用文献 | Structural basis of the specificity of USP18 toward ISG15.
Nat. Struct. Mol. Biol., 24, 2017
|
|
5C1Z
 | | Parkin (UblR0RBR) | | 分子名称: | CHLORIDE ION, E3 ubiquitin-protein ligase parkin, GLYCEROL, ... | | 著者 | kumar, A, Aguirre, J.D, Condos, T.E.C, Martinez-Torres, R.J, Chaugule, V.K, Toth, R, Sundaramoorthy, R, Mercier, P, Knebel, A, Spratt, D.E, Barber, K.R, Shaw, G.S, Walden, H. | | 登録日 | 2015-06-15 | | 公開日 | 2015-07-29 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.79 Å) | | 主引用文献 | Disruption of the autoinhibited state primes the E3 ligase parkin for activation and catalysis.
Embo J., 34, 2015
|
|
5C7J
 | | CRYSTAL STRUCTURE OF NEDD4 WITH A UB VARIANT | | 分子名称: | E3 ubiquitin-protein ligase NEDD4, Polyubiquitin-C | | 著者 | Walker, J.R, Hu, J, Dong, A, Bountra, C, Edwards, A.M, Arrowsmith, C.H, Tong, Y, Structural Genomics Consortium (SGC) | | 登録日 | 2015-06-24 | | 公開日 | 2016-03-16 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | System-Wide Modulation of HECT E3 Ligases with Selective Ubiquitin Variant Probes.
Mol.Cell, 62, 2016
|
|
5CAW
 | |
6SIS
 | | Crystal structure of macrocyclic PROTAC 1 in complex with the second bromodomain of human Brd4 and pVHL:ElonginC:ElonginB | | 分子名称: | Bromodomain-containing protein 4, Elongin-B, Elongin-C, ... | | 著者 | Hughes, S.J, Testa, A, Ciulli, A. | | 登録日 | 2019-08-10 | | 公開日 | 2019-12-04 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | | 主引用文献 | Structure-Based Design of a Macrocyclic PROTAC.
Angew.Chem.Int.Ed.Engl., 59, 2020
|
|
6R6H
 | | Structural basis of Cullin-2 RING E3 ligase regulation by the COP9 signalosome | | 分子名称: | COP9 signalosome complex subunit 1, COP9 signalosome complex subunit 2, COP9 signalosome complex subunit 3, ... | | 著者 | Morris, E.P, Faull, S.V, Lau, A.M.C, Politis, A, Beuron, F, Cronin, N. | | 登録日 | 2019-03-27 | | 公開日 | 2019-08-28 | | 最終更新日 | 2024-05-22 | | 実験手法 | ELECTRON MICROSCOPY (8.4 Å) | | 主引用文献 | Structural basis of Cullin 2 RING E3 ligase regulation by the COP9 signalosome.
Nat Commun, 10, 2019
|
|
5CVM
 | | USP46~ubiquitin BEA covalent complex | | 分子名称: | Polyubiquitin-B, Ubiquitin carboxyl-terminal hydrolase 46, ZINC ION | | 著者 | Harris, S.F, Yin, J. | | 登録日 | 2015-07-27 | | 公開日 | 2015-10-07 | | 最終更新日 | 2015-11-11 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structural Insights into WD-Repeat 48 Activation of Ubiquitin-Specific Protease 46.
Structure, 23, 2015
|
|
5CRA
 | | Structure of the SdeA DUB Domain | | 分子名称: | METHYL 4-AMINOBUTANOATE, Polyubiquitin-B, SULFATE ION, ... | | 著者 | Sheedlo, M.J, Qiu, J, Luo, Z.Q, Das, C. | | 登録日 | 2015-07-22 | | 公開日 | 2015-11-25 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.64 Å) | | 主引用文献 | Structural basis of substrate recognition by a bacterial deubiquitinase important for dynamics of phagosome ubiquitination.
Proc.Natl.Acad.Sci.USA, 112, 2015
|
|
6RYA
 | |
5D6J
 | | Crystal structure of a mycobacterial protein | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Acyl-CoA synthase, MAGNESIUM ION, ... | | 著者 | Li, W.J, Bi, L.J. | | 登録日 | 2015-08-12 | | 公開日 | 2016-03-02 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | | 主引用文献 | Crystal structure of FadD32, an enzyme essential for mycolic acid biosynthesis in mycobacteria.
Sci Rep, 5, 2015
|
|
