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PDB: 596 件

3P27
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Crystal structure of S. cerevisiae Hbs1 protein (GDP-bound form), a translational GTPase involved in RNA quality control pathways and interacting with Dom34/Pelota
分子名称: Elongation factor 1 alpha-like protein, GUANOSINE-5'-DIPHOSPHATE
著者van den Elzen, A, Henri, J, Lazar, N, Gas, M.E, Durand, D, Lacroute, F, Nicaise, M, van Tilbeurgh, H, Sraphin, B, Graille, M, Paris-Sud Yeast Structural Genomics (YSG)
登録日2010-10-01
公開日2010-11-17
最終更新日2012-03-14
実験手法X-RAY DIFFRACTION (2.95 Å)
主引用文献Dissection of Dom34-Hbs1 reveals independent functions in two RNA quality control pathways.
Nat.Struct.Mol.Biol., 17, 2010
3P26
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Crystal structure of S. cerevisiae Hbs1 protein (apo-form), a translational GTPase involved in RNA quality control pathways and interacting with Dom34/Pelota
分子名称: Elongation factor 1 alpha-like protein
著者van den Elzen, A, Henri, J, Lazar, N, Gas, M.E, Durand, D, Lacroute, F, Nicaise, M, van Tilbeurgh, H, Sraphin, B, Graille, M, Paris-Sud Yeast Structural Genomics (YSG)
登録日2010-10-01
公開日2010-11-17
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Dissection of Dom34-Hbs1 reveals independent functions in two RNA quality control pathways.
Nat.Struct.Mol.Biol., 17, 2010
2LKC
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Free B.st IF2-G2
分子名称: Translation initiation factor IF-2
著者Wienk, H, Tishchenko, E, Belardinelli, R, Tomaselli, S, Dongre, R, Spurio, R, Folkers, G.E, Gualerzi, C.O, Boelens, R.
登録日2011-10-10
公開日2012-02-15
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Structural Dynamics of Bacterial Translation Initiation Factor IF2.
J.Biol.Chem., 287, 2012
2LKD
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IF2-G2 GDP complex
分子名称: GUANOSINE-5'-DIPHOSPHATE, Translation initiation factor IF-2
著者Wienk, H, Tishchenko, E, Belardinelli, R, Tomaselli, S, Dongre, R, Spurio, R, Folkers, G.E, Gualerzi, C.O, Boelens, R.
登録日2011-10-10
公開日2012-02-15
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Structural Dynamics of Bacterial Translation Initiation Factor IF2.
J.Biol.Chem., 287, 2012
4TN1
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Translation initiation factor eIF5B (517-858) mutant D533R from C. thermophilum, bound to GTPgammaS
分子名称: 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, MAGNESIUM ION, eIF5B
著者Kuhle, B, Ficner, R.
登録日2014-06-02
公開日2014-09-24
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献A monovalent cation acts as structural and catalytic cofactor in translational GTPases.
Embo J., 33, 2014
4TMW
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Translation initiation factor eIF5B (517-858) from C. thermophilum, bound to GTP and Sodium
分子名称: GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, SODIUM ION, ...
著者Kuhle, B, Ficner, R.
登録日2014-06-02
公開日2014-09-24
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献A monovalent cation acts as structural and catalytic cofactor in translational GTPases.
Embo J., 33, 2014
4TMV
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Translation initiation factor eIF5B (517-858) from C. thermophilum, bound to GTPgammaS and Sodium
分子名称: 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, GLYCEROL, MAGNESIUM ION, ...
著者Kuhle, B, Ficner, R.
登録日2014-06-02
公開日2014-09-24
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.53 Å)
主引用文献A monovalent cation acts as structural and catalytic cofactor in translational GTPases.
Embo J., 33, 2014
4TMT
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Translation initiation factor eIF5B (517-858) mutant D533A from C. thermophilum, bound to GTPgammaS
分子名称: 1,2-ETHANEDIOL, 2,3-DIHYDROXY-1,4-DITHIOBUTANE, 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, ...
著者Kuhle, B, Ficner, R.
登録日2014-06-02
公開日2014-09-24
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.58 Å)
主引用文献A monovalent cation acts as structural and catalytic cofactor in translational GTPases.
Embo J., 33, 2014
4TMX
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Translation initiation factor eIF5B (517-858) mutant D533N from C. thermophilum, bound to GTP and sodium
分子名称: 1,2-ETHANEDIOL, ACETIC ACID, GUANOSINE-5'-TRIPHOSPHATE, ...
著者Kuhle, B, Ficner, R.
登録日2014-06-02
公開日2014-09-24
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献A monovalent cation acts as structural and catalytic cofactor in translational GTPases.
Embo J., 33, 2014
4ZKE
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Crystal structure of the S. cerevisiae Ski7 GTPase-like domain, bound to GTP.
分子名称: GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, SODIUM ION, ...
著者Kowalinski, E, Conti, E.
登録日2015-04-30
公開日2015-06-17
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.251 Å)
主引用文献Saccharomyces cerevisiae Ski7 Is a GTP-Binding Protein Adopting the Characteristic Conformation of Active Translational GTPases.
Structure, 23, 2015
4ZKD
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Crystal structure of the S. cerevisiae Ski7 GTPase-like domain, bound to GDP and inorganic phosphate.
分子名称: GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, PHOSPHATE ION, ...
著者Kowalinski, E, Conti, E.
登録日2015-04-30
公開日2015-06-17
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.181 Å)
主引用文献Saccharomyces cerevisiae Ski7 Is a GTP-Binding Protein Adopting the Characteristic Conformation of Active Translational GTPases.
Structure, 23, 2015
4TMZ
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Translation initiation factor eIF5B (517-858) from C. thermophilum, bound to GTPgammaS and potassium
分子名称: 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, CHLORIDE ION, GLYCEROL, ...
著者Kuhle, B, Ficner, R.
登録日2014-06-02
公開日2014-09-24
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.28 Å)
主引用文献A monovalent cation acts as structural and catalytic cofactor in translational GTPases.
Embo J., 33, 2014
1F60
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CRYSTAL STRUCTURE OF THE YEAST ELONGATION FACTOR COMPLEX EEF1A:EEF1BA
分子名称: ELONGATION FACTOR EEF1A, ELONGATION FACTOR EEF1BA
著者Andersen, G.R, Pedersen, L, Valente, L, Kinzy, T.G, Nyborg, J.
登録日2000-06-19
公開日2000-07-04
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.67 Å)
主引用文献Structural basis for nucleotide exchange and competition with tRNA in the yeast elongation factor complex eEF1A:eEF1Balpha.
Mol.Cell, 6, 2000
5XJC
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Cryo-EM structure of the human spliceosome just prior to exon ligation at 3.6 angstrom
分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ...
著者Zhang, X, Yan, C, Hang, J, Finci, I.L, Lei, J, Shi, Y.
登録日2017-04-30
公開日2017-07-05
最終更新日2020-10-14
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献An Atomic Structure of the Human Spliceosome
Cell, 169, 2017
8V9L
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Cryo-EM structure of the Mycobacterium smegmatis 70S ribosome in complex with hibernation factor Msmeg1130 (Balon) and MsmegEF-Tu(GDP) (Composite structure 6)
分子名称: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S Ribosomal Protein S2, ...
著者Rybak, M.Y, Helena-Bueno, K, Hill, C.H, Melnikov, S.V, Gagnon, M.G.
登録日2023-12-08
公開日2024-02-07
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献A new family of bacterial ribosome hibernation factors.
Nature, 626, 2024
1N0V
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Crystal structure of elongation factor 2
分子名称: Elongation factor 2
著者Joergensen, R, Ortiz, P.A, Carr-Schmid, A, Nissen, P, Kinzy, T.G, Andersen, G.R.
登録日2002-10-15
公開日2002-11-27
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献Two crystal structures demonstrate large conformational changes in the eukaryotic ribosomal translocase.
Nat.Struct.Biol., 10, 2003
3CB4
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The Crystal Structure of LepA
分子名称: GTP-binding protein lepA
著者Evans, R.N, Blaha, G, Bailey, S, Steitz, T.A.
登録日2008-02-21
公開日2008-03-18
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献The structure of LepA, the ribosomal back translocase.
Proc.Natl.Acad.Sci.Usa, 105, 2008
2FX3
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Crystal Structure Determination of E. coli Elongation Factor, Tu using a Twinned Data Set
分子名称: Elongation factor Tu, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION
著者Heffron, S.E, Moeller, R, Jurnak, F.
登録日2006-02-03
公開日2006-03-28
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献Solving the structure of Escherichia coli elongation factor Tu using a twinned data set.
Acta Crystallogr.,Sect.D, 62, 2006
7SYV
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Structure of the wt IRES eIF5B-containing pre-48S initiation complex, open conformation. Structure 14(wt)
分子名称: 18S rRNA, 40S ribosomal protein S2, 40S ribosomal protein S21, ...
著者Brown, Z.P, Abaeva, I.S, De, S, Hellen, C.U.T, Pestova, T.V, Frank, J.
登録日2021-11-25
公開日2022-07-20
最終更新日2023-02-01
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Molecular architecture of 40S translation initiation complexes on the hepatitis C virus IRES.
Embo J., 41, 2022
5OT7
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Elongation factor G-ribosome complex captures in the absence of inhibitors.
分子名称: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ...
著者Mace, K, Giudice, E, Chat, S, Gillet, R.
登録日2017-08-21
公開日2018-02-14
最終更新日2018-04-11
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献The structure of an elongation factor G-ribosome complex captured in the absence of inhibitors.
Nucleic Acids Res., 46, 2018
5DSZ
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Gamma-subunit of the translation initiation factor 2 from S. solfataricus
分子名称: Translation initiation factor 2 subunit gamma
著者Kravchenko, O.V, Nikonov, O.S, Stolboushkina, E.A, Nevskaya, N.A, Nikulin, A.D, Garber, M.B, Nikonov, S.V.
登録日2015-09-17
公開日2016-08-24
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Gamma-subunit of the translation initiation factor 2 from S. solfataricus
To Be Published
7L20
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Cryo-EM structure of the human 39S mitoribosomal subunit in complex with RRFmt and EF-G2mt.
分子名称: 16S rRNA mitochondrial, 39 S P-site finger, 39S ribosomal protein L10, ...
著者Agrawal, E, Koripella, R.
登録日2020-12-15
公開日2021-05-12
最終更新日2021-12-01
実験手法ELECTRON MICROSCOPY (3.15 Å)
主引用文献Distinct mechanisms of the human mitoribosome recycling and antibiotic resistance.
Nat Commun, 12, 2021
2RDO
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50S subunit with EF-G(GDPNP) and RRF bound
分子名称: 23S RIBOSOMAL RNA, 50S ribosomal protein L1, 50S ribosomal protein L11, ...
著者Gao, N, Zavialov, A.V, Ehrenberg, M, Frank, J.
登録日2007-09-24
公開日2008-03-04
最終更新日2024-02-21
実験手法ELECTRON MICROSCOPY (9.1 Å)
主引用文献Specific interaction between EF-G and RRF and its implication for GTP-dependent ribosome splitting into subunits.
J.Mol.Biol., 374, 2007
5G06
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Cryo-EM structure of yeast cytoplasmic exosome
分子名称: EXOSOME COMPLEX COMPONENT CSL4, EXOSOME COMPLEX COMPONENT MTR3, EXOSOME COMPLEX COMPONENT RRP4, ...
著者Liu, J.J, Niu, C.Y, Wu, Y, Tan, D, Wang, Y, Ye, M.D, Liu, Y, Zhao, W.W, Zhou, K, Liu, Q.S, Dai, J.B, Yang, X.R, Dong, M.Q, Huang, N, Wang, H.W.
登録日2016-03-17
公開日2016-06-15
最終更新日2017-08-02
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献Cryoem Structure of Yeast Cytoplasmic Exosome Complex.
Cell Res., 26, 2016
4V5M
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tRNA tranlocation on the 70S ribosome: the pre-translocational translocation intermediate TI(PRE)
分子名称: 16S RRNA, 23S RIBOSOMAL RNA, 30S RIBOSOMAL PROTEIN S10, ...
著者Ratje, A.H, Loerke, J, Mikolajka, A, Bruenner, M, Hildebrand, P.W, Starosta, A.L, Doenhoefer, A, Connell, S.R, Fucini, P, Mielke, T, Whitford, P.C, Onuchic, J.N, Yu, Y, Sanbonmatsu, K.Y, Hartmann, R.K, Penczek, P.A, Wilson, D.N, Spahn, C.M.T.
登録日2010-10-01
公開日2014-07-09
最終更新日2019-12-11
実験手法ELECTRON MICROSCOPY (7.8 Å)
主引用文献Head Swivel on the Ribosome Facilitates Translocation by Means of Intra-Subunit tRNA Hybrid Sites.
Nature, 468, 2010

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