3P27

Crystal structure of S. cerevisiae Hbs1 protein (GDP-bound form), a translational GTPase involved in RNA quality control pathways and interacting with Dom34/Pelota

Summary for 3P27

• Entry DOI: 10.2210/pdb3p27/pdb
• Related: 3P26
• Descriptor: Elongation factor 1 alpha-like protein, GUANOSINE-5'-DIPHOSPHATE (3 entities in total)
• Functional Keywords: gdp/gtp binding domain, beta-barrel, translational gtpase, structural genomics, paris-sud yeast structural genomics, ysg, signaling protein
• Biological source: Saccharomyces cerevisiae (brewer's yeast,lager beer yeast,yeast)
• Cellular location: Cytoplasm: P32769
• Total number of polymer chains: 2
• Total formula weight: 110573.75

Authors

van den Elzen, A.,Henri, J.,Lazar, N.,Gas, M.E.,Durand, D.,Lacroute, F.,Nicaise, M.,van Tilbeurgh, H.,Sraphin, B.,Graille, M.,Paris-Sud Yeast Structural Genomics (YSG) (deposition date: 2010-10-01, release date: 2010-11-17, Last modification date: 2012-03-14)

• Primary citation: van den Elzen, A.M.,Henri, J.,Lazar, N.,Gas, M.E.,Durand, D.,Lacroute, F.,Nicaise, M.,van Tilbeurgh, H.,Seraphin, B.,Graille, M.; Dissection of Dom34-Hbs1 reveals independent functions in two RNA quality control pathways.; Nat.Struct.Mol.Biol., 17:1446-1452, 2010; PubMed: 21102444; DOI: 10.1038/nsmb.1963

Experimental method

X-RAY DIFFRACTION (2.95 Å)