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PDB: 1192 件

8GVI
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The complex between H25-11 TCR and HLA-A24 bound to HIV-1 Nef138-8 peptide
分子名称: 8-mer peptide from Protein Nef, Beta-2-microglobulin, H25-11 TCR alpha chain, ...
著者Gao, G.F, Shi, Y, Tan, S, Ma, K, Chai, Y, Qi, J, Kawana-Tachikawa, A, Iwamoto, A, Dong, T, Guan, J.
登録日2022-09-15
公開日2022-10-19
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Molecular Basis for the Recognition of HIV Nef138-8 Epitope by a Pair of Human Public T Cell Receptors.
J Immunol., 209, 2022
5KNM
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Human leukocyte antigen F (HLA-F) presents peptides and regulates immunity through interactions with NK-cell receptors
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-2-microglobulin, Leukocyte immunoglobulin-like receptor subfamily B member 1, ...
著者Dulberger, C.L, Adams, E.J.
登録日2016-06-28
公開日2017-06-14
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Human Leukocyte Antigen F Presents Peptides and Regulates Immunity through Interactions with NK Cell Receptors.
Immunity, 46, 2017
4PJ8
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Structure of human MR1-5-OP-RU in complex with human MAIT TRBV20 TCR
分子名称: 1-deoxy-1-({2,6-dioxo-5-[(E)-propylideneamino]-1,2,3,6-tetrahydropyrimidin-4-yl}amino)-D-ribitol, Beta-2-microglobulin, Major histocompatibility complex class I-related gene protein, ...
著者Birkinshaw, R.W, Rossjohn, J.
登録日2014-05-12
公開日2014-07-02
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献A molecular basis underpinning the T cell receptor heterogeneity of mucosal-associated invariant T cells.
J.Exp.Med., 211, 2014
6MWR
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Recognition of MHC-like molecule
分子名称: 1-deoxy-1-({2,6-dioxo-5-[(E)-propylideneamino]-1,2,3,6-tetrahydropyrimidin-4-yl}amino)-D-ribitol, 2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-2-microglobulin, ...
著者Le Nours, J, Rossjohn, J.
登録日2018-10-30
公開日2019-12-18
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献A class of gamma delta T cell receptors recognize the underside of the antigen-presenting molecule MR1.
Science, 366, 2019
5OPI
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Crystal structure of the TAPBPR-MHC I peptide editing complex
分子名称: Beta-2-microglobulin, H-2 class I histocompatibility antigen, D-B alpha chain, ...
著者Thomas, C, Tampe, R.
登録日2017-08-09
公開日2017-10-18
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Structure of the TAPBPR-MHC I complex defines the mechanism of peptide loading and editing.
Science, 358, 2017
6NCA
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HLA-A2 (A*02:01) bound to a peptide from the Epstein-Barr virus BRLF1 protein
分子名称: Beta-2-microglobulin, HLA class I histocompatibility antigen, A-2 alpha chain, ...
著者Stern, L.J, Selin, L.K, Song, I.Y.
登録日2018-12-11
公開日2019-10-23
最終更新日2020-01-29
実験手法X-RAY DIFFRACTION (3.300001 Å)
主引用文献CDR3 alpha drives selection of the immunodominant Epstein Barr virus (EBV) BRLF1-specific CD8 T cell receptor repertoire in primary infection.
Plos Pathog., 15, 2019
7Q15
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Crystal structure of FcRn and beta-2-microglobulin in complex with IgG1-Fc-MST-HN (efgartigimod)
分子名称: Beta-2-microglobulin, IgG receptor FcRn large subunit p51, IgG1-Fc-MST-HN, ...
著者Pannecoucke, E, Savvides, S.N.
登録日2021-10-18
公開日2022-09-28
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (3.301 Å)
主引用文献The Fab region of IgG impairs the internalization pathway of FcRn upon Fc engagement.
Nat Commun, 13, 2022
6AEE
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Crystal structure of the four Ig-like domains of LILRB1 complexed with HLA-G
分子名称: 9 Mer Peptide (RL9) From Histone H2A.x, Beta-2-microglobulin, HLA class I histocompatibility antigen, ...
著者Wang, Q, Song, H, Qi, J, Gao, G.F.
登録日2018-08-04
公開日2019-07-31
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (3.303 Å)
主引用文献Structures of the four Ig-like domain LILRB2 and the four-domain LILRB1 and HLA-G1 complex.
Cell. Mol. Immunol., 2019
5W1V
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Structure of the HLA-E-VMAPRTLIL/GF4 TCR complex
分子名称: Beta-2-microglobulin, GF4 T cell receptor alpha chain, GF4 T cell receptor beta chain, ...
著者Gras, S, Walpole, N, Farenc, C, Rossjohn, J.
登録日2017-06-04
公開日2017-10-04
最終更新日2020-01-01
実験手法X-RAY DIFFRACTION (3.31 Å)
主引用文献A conserved energetic footprint underpins recognition of human leukocyte antigen-E by two distinct alpha beta T cell receptors.
J. Biol. Chem., 292, 2017
8RH6
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Crystal structure of HLA-A*11:01 in complex with SVLNDILSRL, an 10-mer epitope from SARS-CoV-2 Spike (S975-984)
分子名称: 1,2-ETHANEDIOL, Beta-2-microglobulin, DI(HYDROXYETHYL)ETHER, ...
著者Ahn, Y.M, Maddumage, J.C, Szeto, C, Gras, S.
登録日2023-12-15
公開日2024-05-15
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (3.32 Å)
主引用文献The impact of SARS-CoV-2 spike mutation on peptide presentation is HLA allomorph-specific.
Curr Res Struct Biol, 7, 2024
7RM4
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Neoantigen p53R175H-specific TCR 6-11 binds to p53R175H-HLA-A2
分子名称: 6-11 T cell receptor alpha chain, 6-11 T cell receptor beta chain, Beta-2-microglobulin, ...
著者Wu, D, Mariuzza, R.A.
登録日2021-07-26
公開日2022-02-09
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (3.33 Å)
主引用文献T cell receptors employ diverse strategies to target a p53 cancer neoantigen.
J.Biol.Chem., 298, 2022
8I5C
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Crystal structure of a TCR in complex with HLA-A*11:01 bound to KRAS peptide (VVGAVGVGK)
分子名称: Beta-2-microglobulin, MHC class I antigen (Fragment), TCR alpha chain, ...
著者Lu, D, Chen, Y, Jiang, M, Tan, S.G, Chai, Y, Gao, G.F.
登録日2023-01-24
公開日2023-08-23
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (3.34 Å)
主引用文献Crystal structure of a TCR in complex with HLA-A*11:01 bound to KRAS peptide (VVGAVGVGK)
Nat Commun, 2023
6BJ2
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TCR589 in complex with HIV(Pol448-456)/HLA-B35
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-2-microglobulin, ...
著者Jude, K.M, Sibener, L.V, Garcia, K.C.
登録日2017-11-03
公開日2018-07-25
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3.35 Å)
主引用文献Isolation of a Structural Mechanism for Uncoupling T Cell Receptor Signaling from Peptide-MHC Binding.
Cell, 174, 2018
8GVG
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The complex between public TCR TD08 and HLA-A24 bound to HIV-1 Nef138-8 (2F) peptide
分子名称: Beta-2-microglobulin, MHC class I antigen, TD08 TCR alpha chain, ...
著者Gao, G.F, Shi, Y, Ma, K, Chai, Y, Guan, J, Qi, J, Tan, S, Dong, T, Iwamoto, A, Kawana-Tachikawa, A.
登録日2022-09-15
公開日2022-10-19
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (3.37 Å)
主引用文献Molecular Basis for the Recognition of HIV Nef138-8 Epitope by a Pair of Human Public T Cell Receptors.
J Immunol., 209, 2022
3CDG
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Human CD94/NKG2A in complex with HLA-E
分子名称: Beta-2-microglobulin, HLA class I histocompatibility antigen, alpha chain E, ...
著者Petrie, E.J, Clements, C.S, Lin, J, Sullivan, L.C, Johnson, D, Huyton, T, Heroux, A, Hoare, H.L, Beddoe, T, Reid, H.H, Wilce, M.C.J, Brooks, A.G, Rossjohn, J.
登録日2008-02-26
公開日2008-04-22
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献CD94-NKG2A recognition of human leukocyte antigen (HLA)-E bound to an HLA class I leader sequence
J.Exp.Med., 205, 2008
6ILM
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Cryo-EM structure of Echovirus 6 complexed with its uncoating receptor FcRn at PH 7.4
分子名称: Beta-2-microglobulin, Capsid protein VP1, Capsid protein VP2, ...
著者Gao, G.F, Liu, S, Zhao, X, Peng, R.
登録日2018-10-19
公開日2019-05-15
最終更新日2019-11-06
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Human Neonatal Fc Receptor Is the Cellular Uncoating Receptor for Enterovirus B.
Cell, 177, 2019
1YPZ
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Immune receptor
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-2-microglobulin, ...
著者Adams, E.J, Garcia, K.C.
登録日2005-01-31
公開日2005-04-12
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献Structure of a gammadelta T cell receptor in complex with the nonclassical MHC T22.
Science, 308, 2005
1P7Q
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Crystal Structure of HLA-A2 Bound to LIR-1, a Host and Viral MHC Receptor
分子名称: Beta-2-microglobulin, HLA class I histocompatibility antigen, A-2 alpha chain, ...
著者Willcox, B.E, Thomas, L.M, Bjorkman, P.J.
登録日2003-05-05
公開日2003-10-14
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献Crystal structure of HLA-A2 bound to LIR-1, a host and viral major histocompatibility complex receptor.
Nat.Immunol., 4, 2003
5D7L
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Structure of human MR1-5-OP-RU in complex with human MAV36 TCR
分子名称: 1-deoxy-1-({2,6-dioxo-5-[(E)-propylideneamino]-1,2,3,6-tetrahydropyrimidin-4-yl}amino)-D-ribitol, Beta-2-microglobulin, MAV36 TCR Alpha Chain, ...
著者Keller, A.N, Rossjohn, J.
登録日2015-08-14
公開日2016-01-27
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献Diversity of T Cells Restricted by the MHC Class I-Related Molecule MR1 Facilitates Differential Antigen Recognition.
Immunity, 44, 2016
8ESA
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CryoEM structure of HLA-A2 bound to MAGEA4 (230-239) peptide
分子名称: Beta-2-microglobulin,HLA class I antigen,MAGE-A4 peptide chimera
著者Saotome, K, Franklin, M.C.
登録日2022-10-13
公開日2023-05-03
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Structural analysis of cancer-relevant TCR-CD3 and peptide-MHC complexes by cryoEM.
Nat Commun, 14, 2023
8A7P
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beta-2-microglobulin DeltaN6 amyloid fibril form 2PFb
分子名称: Beta-2-microglobulin form pI 5.3
著者Wilkinson, M, Gallardo, R, Radford, S.E, Ranson, N.A.
登録日2022-06-21
公開日2023-03-22
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Disease-relevant beta 2 -microglobulin variants share a common amyloid fold.
Nat Commun, 14, 2023
7PB2
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Crystal structure of JDI TCR in complex with HLA-A*11:01 bound to KRAS G12D peptide (VVVGADGVGK)
分子名称: Beta-2-microglobulin, KRAS G12D peptide (VVVGADGVGK), MHC class I antigen, ...
著者Coles, C.H, Karuppiah, V, Robinson, R.A.
登録日2021-07-30
公開日2022-07-20
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (3.41 Å)
主引用文献Therapeutic high affinity T cell receptor targeting a KRASG12D cancer neoantigen
Nat Commun, 13, 2022
5WER
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Crystal Structure of TAPBPR and H2-Dd complex
分子名称: 1,2-ETHANEDIOL, Beta-2-microglobulin, CITRIC ACID, ...
著者Jiang, J.S, Natarajan, K, Boyd, L.F, Margulies, D.H.
登録日2017-07-10
公開日2017-10-18
最終更新日2019-08-28
実験手法X-RAY DIFFRACTION (3.412 Å)
主引用文献Crystal structure of a TAPBPR-MHC I complex reveals the mechanism of peptide editing in antigen presentation.
Science, 358, 2017
6UON
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Molecular basis for tumor infiltrating TCR recognition of hotspot KRAS-G12D mutation
分子名称: Beta-2-microglobulin, GLY-ALA-ASP-GLY-VAL-GLY-LYS-SER-ALA-LEU, HLA class I antigen, ...
著者Sun, P.D, Sim, M.J.W.
登録日2019-10-15
公開日2020-05-27
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献High-affinity oligoclonal TCRs define effective adoptive T cell therapy targeting mutant KRAS-G12D.
Proc.Natl.Acad.Sci.USA, 117, 2020
1HLA
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STRUCTURE OF THE HUMAN CLASS I HISTOCOMPATIBILITY ANTIGEN, HLA-A2
分子名称: BETA 2-MICROGLOBULIN, CLASS I HISTOCOMPATIBILITY ANTIGEN (HLA-A2) (ALPHA CHAIN)
著者Bjorkman, P.J, Saper, M.A, Samraoui, B, Bennett, W.S, Strominger, J.L, Wiley, D.C.
登録日1987-10-15
公開日1988-01-16
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Structure of the human class I histocompatibility antigen, HLA-A2.
Nature, 329, 1987

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