6WNA
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![BU of 6wna by Molmil](/molmil-images/mine/6wna) | Next generation monomeric IgG4 Fc | 分子名称: | Beta-2-microglobulin, IgG receptor FcRn large subunit p51, Immunoglobulin heavy constant gamma 4, ... | 著者 | Oganesyan, V.Y, Shan, L, van Dyk, N, Dall'Acqua, W.F. | 登録日 | 2020-04-22 | 公開日 | 2021-09-15 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | In vivo pharmacokinetic enhancement of monomeric Fc and monovalent bispecific designs through structural guidance. Commun Biol, 4, 2021
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3KYN
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![BU of 3kyn by Molmil](/molmil-images/mine/3kyn) | Crystal structure of HLA-G presenting KGPPAALTL peptide | 分子名称: | Beta-2-microglobulin, CHLORIDE ION, COBALT (II) ION, ... | 著者 | Walpole, N.G, Rossjohn, J, Clements, C.S. | 登録日 | 2009-12-06 | 公開日 | 2010-02-23 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | The structure and stability of the monomorphic HLA-G are influenced by the nature of the bound peptide J.Mol.Biol., 397, 2010
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3L3J
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![BU of 3l3j by Molmil](/molmil-images/mine/3l3j) | Crystal structure of HLA-B*4402 in complex with the F3A/R5A double mutant of a self-peptide derived from DPA*0201 | 分子名称: | ACETATE ION, Beta-2-microglobulin, HLA class I histocompatibility antigen, ... | 著者 | Theodossis, A, Ely, L.K, Rossjohn, J. | 登録日 | 2009-12-17 | 公開日 | 2010-03-16 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Constraints within major histocompatibility complex class I restricted peptides: presentation and consequences for T-cell recognition Proc.Natl.Acad.Sci.USA, 107, 2010
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4WU5
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![BU of 4wu5 by Molmil](/molmil-images/mine/4wu5) | HLA-A24 in complex with HIV-1 Nef134-8(wt) | 分子名称: | 8-Mer peptide from Protein Nef, Beta-2-microglobulin, HLA class I histocompatibility antigen, ... | 著者 | Shimizu, A, Yamagata, A, Fukai, S, Iwamoto, A. | 登録日 | 2014-10-31 | 公開日 | 2015-05-06 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Crystal structure of Nef134-8(wt) epitope presented by HLA-A24 To Be Published
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5C9J
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![BU of 5c9j by Molmil](/molmil-images/mine/5c9j) | Human CD1c with ligands in A' and F' channel | 分子名称: | Beta-2-microglobulin, GLYCEROL, LAURIC ACID, ... | 著者 | Tews, I, Machelett, M.M, Mansour, S, Gadola, S.D. | 登録日 | 2015-06-27 | 公開日 | 2016-03-02 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Cholesteryl esters stabilize human CD1c conformations for recognition by self-reactive T cells. Proc.Natl.Acad.Sci.USA, 113, 2016
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7K80
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![BU of 7k80 by Molmil](/molmil-images/mine/7k80) | KIR3DL1*001 in complex with HLA-A*24:02 presenting the RYPLTFGW peptide | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, ARG-TYR-PRO-LEU-THR-PHE-GLY-TRP, ... | 著者 | MacLachlan, B.J, Rossjohn, J, Vivian, J.P. | 登録日 | 2020-09-24 | 公開日 | 2020-12-09 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | The Role of the HLA Class I alpha 2 Helix in Determining Ligand Hierarchy for the Killer Cell Ig-like Receptor 3DL1. J Immunol., 206, 2021
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8TUB
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![BU of 8tub by Molmil](/molmil-images/mine/8tub) | HLA B7:02 with HPNGYKSLSTL | 分子名称: | 1,2-ETHANEDIOL, Beta-2-microglobulin, DI(HYDROXYETHYL)ETHER, ... | 著者 | Littler, D.R, Rossjohn, J, Chaurasia, P, Petersen, J. | 登録日 | 2023-08-16 | 公開日 | 2024-03-13 | 最終更新日 | 2024-05-15 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | CD8 + T-cell responses towards conserved influenza B virus epitopes across anatomical sites and age. Nat Commun, 15, 2024
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7AFV
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![BU of 7afv by Molmil](/molmil-images/mine/7afv) | Crystal structure of tetrameric beta-2-microglobulin deltaN6 S52C stabilized by a covalent ligand | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 5-oxidanylidene-~{N}-(2-sulfanylethyl)-2,3-dihydro-[1,3]thiazolo[3,2-a]pyrimidine-6-carboxamide, Beta-2-microglobulin | 著者 | Guthertz, N, Cawood, E, Karamanos, T. | 登録日 | 2020-09-20 | 公開日 | 2020-12-09 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Modulation of Amyloidogenic Protein Self-Assembly Using Tethered Small Molecules. J.Am.Chem.Soc., 142, 2020
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1Q94
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![BU of 1q94 by Molmil](/molmil-images/mine/1q94) | Structures of HLA-A*1101 in complex with immunodominant nonamer and decamer HIV-1 epitopes clearly reveal the presence of a middle anchor residue | 分子名称: | Beta-2-microglobulin, HLA class I histocompatibility antigen, A-11 alpha chain, ... | 著者 | Li, L, McNicholl, J.M, Bouvier, M. | 登録日 | 2003-08-22 | 公開日 | 2004-06-01 | 最終更新日 | 2020-02-05 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Structures of HLA-A*1101 complexed with immunodominant nonamer and decamer HIV-1 epitopes clearly reveal the presence of a middle, secondary anchor residue. J.Immunol., 172, 2004
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7UMG
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![BU of 7umg by Molmil](/molmil-images/mine/7umg) | Crystal structure of human CD8aa-MR1-Ac-6-FP complex | 分子名称: | Beta-2-microglobulin, CHLORIDE ION, Major histocompatibility complex class I-related gene protein, ... | 著者 | Awad, W, Rossjohn, J. | 登録日 | 2022-04-06 | 公開日 | 2022-08-03 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | CD8 coreceptor engagement of MR1 enhances antigen responsiveness by human MAIT and other MR1-reactive T cells. J.Exp.Med., 219, 2022
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5GR7
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![BU of 5gr7 by Molmil](/molmil-images/mine/5gr7) | Mouse MHC class I H-2Kd with a MERS-CoV-derived peptide 37-1 | 分子名称: | Beta-2-microglobulin, H-2 class I histocompatibility antigen, K-D alpha chain, ... | 著者 | Liu, K, Chai, Y, Qi, J, Tan, W, Liu, W.J, Gao, G.F. | 登録日 | 2016-08-08 | 公開日 | 2017-06-07 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Protective T Cell Responses Featured by Concordant Recognition of Middle East Respiratory Syndrome Coronavirus-Derived CD8+ T Cell Epitopes and Host MHC. J. Immunol., 198, 2017
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8DV4
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![BU of 8dv4 by Molmil](/molmil-images/mine/8dv4) | Crystal structure of the BC8B TCR-CD1b-PI complex | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOINOSITOL, 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Farquhar, R, Rossjohn, J, Shahine, A. | 登録日 | 2022-07-28 | 公開日 | 2023-04-19 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | alpha beta T-cell receptor recognition of self-phosphatidylinositol presented by CD1b. J.Biol.Chem., 299, 2023
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6ID4
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![BU of 6id4 by Molmil](/molmil-images/mine/6id4) | Defining the structural basis for human alloantibody binding to human leukocyte antigen allele HLA-A*11:01 | 分子名称: | Beta-2-microglobulin, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... | 著者 | Lescar, J, Wong, Y.H, Liew, C.W, Gu, Y, MacAry, P.A. | 登録日 | 2018-09-08 | 公開日 | 2019-02-06 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Defining the structural basis for human alloantibody binding to human leukocyte antigen allele HLA-A*11:01. Nat Commun, 10, 2019
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3I6L
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![BU of 3i6l by Molmil](/molmil-images/mine/3i6l) | Newly identified epitope N1 derived from SARS-CoV N protein complexed with HLA-A*2402 | 分子名称: | Beta-2-microglobulin, HLA class I histocompatibility antigen, A-24 alpha chain, ... | 著者 | Liu, J.W. | 登録日 | 2009-07-07 | 公開日 | 2010-07-14 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Novel immunodominant peptide presentation strategy: a featured HLA-A*2402-restricted cytotoxic T-lymphocyte epitope stabilized by intrachain hydrogen bonds from severe acute respiratory syndrome coronavirus nucleocapsid protein J.Virol., 84, 2010
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6V7Y
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![BU of 6v7y by Molmil](/molmil-images/mine/6v7y) | |
4G8G
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![BU of 4g8g by Molmil](/molmil-images/mine/4g8g) | Crystal Structure of C12C TCR-HA B2705-KK10 | 分子名称: | Beta-2-microglobulin, HLA class I histocompatibility antigen, B-27 alpha chain, ... | 著者 | Gras, S, Wilmann, P.G, Rossjohn, J. | 登録日 | 2012-07-23 | 公開日 | 2013-03-20 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | A Molecular Basis for the Control of Preimmune Escape Variants by HIV-Specific CD8(+) T Cells. Immunity, 38, 2013
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4PJG
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![BU of 4pjg by Molmil](/molmil-images/mine/4pjg) | |
7KP0
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![BU of 7kp0 by Molmil](/molmil-images/mine/7kp0) | CD1a-42:1 SM binary complex | 分子名称: | (4R,7S)-4-hydroxy-7-[(1S,2E)-1-hydroxyhexadec-2-en-1-yl]-N,N,N-trimethyl-4,9-dioxo-3,5-dioxa-8-aza-4lambda~5~-phosphadotriacontan-1-aminium, 1,2-ETHANEDIOL, Beta-2-microglobulin, ... | 著者 | Wegrecki, M, Le Nours, J, Rossjohn, J. | 登録日 | 2020-11-10 | 公開日 | 2021-05-05 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | CD1a selectively captures endogenous cellular lipids that broadly block T cell response. J.Exp.Med., 218, 2021
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4K71
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![BU of 4k71 by Molmil](/molmil-images/mine/4k71) | Crystal structure of a high affinity Human Serum Albumin variant bound to the Neonatal Fc Receptor | 分子名称: | Beta-2-microglobulin, IgG receptor FcRn large subunit p51, SULFATE ION, ... | 著者 | Schmidt, M.M, Townson, S.A, Andreucci, A, Dombrowski, C, Erbe, D.V, King, B, Kovalchin, J.T, Masci, A, Murillo, A, Schirmer, E.B, Furfine, E.S, Barnes, T.M. | 登録日 | 2013-04-16 | 公開日 | 2013-10-23 | 最終更新日 | 2014-02-05 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Crystal structure of an HSA/FcRn complex reveals recycling by competitive mimicry of HSA ligands at a pH-dependent hydrophobic interface. Structure, 21, 2013
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5FA4
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![BU of 5fa4 by Molmil](/molmil-images/mine/5fa4) | Structure of HLA-A2:01 with peptide Y16R | 分子名称: | Beta-2-microglobulin, GLYCEROL, HLA class I histocompatibility antigen, ... | 著者 | Remesh, S.G, Zajonc, D.M. | 登録日 | 2015-12-10 | 公開日 | 2016-12-21 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Unconventional Peptide Presentation by Major Histocompatibility Complex (MHC) Class I Allele HLA-A*02:01: BREAKING CONFINEMENT. J. Biol. Chem., 292, 2017
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5BS0
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![BU of 5bs0 by Molmil](/molmil-images/mine/5bs0) | MAGE-A3 Reactive TCR in complex with Titin Epitope in HLA-A1 | 分子名称: | Beta-2-microglobulin, GLYCEROL, HLA class I histocompatibility antigen, ... | 著者 | Raman, M.C.C, Rizkallah, P.J, Simmons, R, Donellan, Z, Dukes, J, Bossi, G, LeProvost, G, Mahon, T, Hickman, E, Lomax, M, Oates, J, Hassan, N, Vuidepot, A, Sami, M, Cole, D.K, Jakobsen, B.K. | 登録日 | 2015-06-01 | 公開日 | 2016-03-02 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Direct molecular mimicry enables off-target cardiovascular toxicity by an enhanced affinity TCR designed for cancer immunotherapy. Sci Rep, 6, 2016
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3VXR
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![BU of 3vxr by Molmil](/molmil-images/mine/3vxr) | The complex between H27-14 TCR and HLA-A24 bound to HIV-1 Nef134-10(wt) peptide | 分子名称: | 10-mer peptide from Protein Nef, Beta-2-microglobulin, H27-14 TCR alpha chain, ... | 著者 | Shimizu, A, Fukai, S, Yamagata, A, Iwamoto, A. | 登録日 | 2012-09-20 | 公開日 | 2013-10-23 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Structure of TCR and antigen complexes at an immunodominant CTL epitope in HIV-1 infection SCI REP, 3, 2013
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5HGB
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![BU of 5hgb by Molmil](/molmil-images/mine/5hgb) | HLA*A2402 complexed with HIV nef138 8mer epitope | 分子名称: | Beta-2-microglobulin, HLA class I histocompatibility antigen, A-24 alpha chain, ... | 著者 | Shi, Y, Qi, J, Gao, G.F. | 登録日 | 2016-01-08 | 公開日 | 2016-06-08 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Effects of a Single Escape Mutation on T Cell and HIV-1 Co-adaptation. Cell Rep, 15, 2016
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2YPL
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![BU of 2ypl by Molmil](/molmil-images/mine/2ypl) | Structural features underlying T-cell receptor sensitivity to concealed MHC class I micropolymorphisms | 分子名称: | AGA T-CELL RECEPTOR ALPHA CHAIN, AGA T-CELL RECEPTOR BETA CHAIN, BETA-2-MICROGLOBULIN, ... | 著者 | Stewart-Jones, G.B, Simpson, P, van der Merwe, P.A, Easterbrook, P, McMichael, A.J, Rowland-Jones, S.L, Jones, E.Y, Gillespie, G.M. | 登録日 | 2012-10-30 | 公開日 | 2012-11-28 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Structural Features Underlying T-Cell Receptor Sensitivity to Concealed Mhc Class I Micropolymorphisms. Proc.Natl.Acad.Sci.USA, 109, 2012
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4PRI
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![BU of 4pri by Molmil](/molmil-images/mine/4pri) | Crystal structure of TK3 TCR-HLA-B*35:08-HPVG complex | 分子名称: | Beta-2-microglobulin, CHLORIDE ION, Epstein-Barr nuclear antigen 1, ... | 著者 | Yu Chih, L, Rossjohn, J, Gras, S. | 登録日 | 2014-03-05 | 公開日 | 2014-04-16 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | A Molecular Basis for the Interplay between T Cells, Viral Mutants, and Human Leukocyte Antigen Micropolymorphism. J.Biol.Chem., 289, 2014
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