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PDB: 1179 件

4GKN
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A2-MHC Complex carrying FATGIGIITV
分子名称: Beta-2-microglobulin, FAT Cognate peptide, MHC class I antigen, ...
著者Sewell, A.K, Rizkallah, P.J, Cole, D.K, Wooldridge, L, Price, D.A.
登録日2012-08-13
公開日2012-09-12
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.753 Å)
主引用文献T-cell Receptor-optimized Peptide Skewing of the T-cell Repertoire Can Enhance Antigen Targeting.
J.Biol.Chem., 287, 2012
4PJD
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BU of 4pjd by Molmil
Structure of human MR1-5-OP-RU in complex with human MAIT C-C10 TCR
分子名称: 1-deoxy-1-({2,6-dioxo-5-[(E)-propylideneamino]-1,2,3,6-tetrahydropyrimidin-4-yl}amino)-D-ribitol, Beta-2-microglobulin, GLYCEROL, ...
著者Birkinshaw, R.W, Rossjohn, J.
登録日2014-05-12
公開日2014-07-02
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.78 Å)
主引用文献A molecular basis underpinning the T cell receptor heterogeneity of mucosal-associated invariant T cells.
J.Exp.Med., 211, 2014
8GOM
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SARS-CoV-2 specific private TCR RLQ7 in complex with RLQ-HLA-A2
分子名称: Beta-2-microglobulin, MHC class I antigen, SARS-CoV-2 specific private TCR RLQ7 alpha, ...
著者Wu, D, Mariuzza, R.A.
登録日2022-08-25
公開日2023-03-01
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.783 Å)
主引用文献Structural insights into protection against a SARS-CoV-2 spike variant by T cell receptor (TCR) diversity.
J.Biol.Chem., 299, 2023
5XOT
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Crystal structure of pHLA-B35 in complex with TU55 T cell receptor
分子名称: An HIV reverse transcriptase epitope, Beta-2-microglobulin, GLYCEROL, ...
著者Shi, Y, Qi, J, Gao, G.F.
登録日2017-05-31
公開日2017-06-14
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.787 Å)
主引用文献Conserved V delta 1 Binding Geometry in a Setting of Locus-Disparate pHLA Recognition by delta / alpha beta T Cell Receptors (TCRs): Insight into Recognition of HIV Peptides by TCRs.
J. Virol., 91, 2017
5WWU
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Crystal Structure of HLA-A*2402 in complex with 2009 pandemic influenza A(H1N1) virus and avian influenza A(H5N1) virus-derived peptide H1-25
分子名称: Beta-2-microglobulin, HLA class I histocompatibility antigen, A-24 alpha chain, ...
著者Zhao, M, Liu, K, Chai, Y, Qi, J, Liu, J, Gao, G.F.
登録日2017-01-05
公開日2018-01-17
最終更新日2019-07-31
実験手法X-RAY DIFFRACTION (2.794 Å)
主引用文献Heterosubtypic Protections against Human-Infecting Avian Influenza Viruses Correlate to Biased Cross-T-Cell Responses.
Mbio, 9, 2018
3QZW
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BU of 3qzw by Molmil
Plasticity of human CD8 binding to peptide-HLA-A*2402
分子名称: 10-mer peptide from Protein Nef, Beta-2-microglobulin, HLA class I histocompatibility antigen, ...
著者Shi, Y, Qi, J, Gao, G.F.
登録日2011-03-07
公開日2011-06-29
最終更新日2013-07-03
実験手法X-RAY DIFFRACTION (2.798 Å)
主引用文献Plasticity of human CD8alpha alpha binding to peptide-HLA-A*2402
Mol.Immunol., 48, 2011
4I48
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BU of 4i48 by Molmil
Structure of HLA-A68 complexed with an HIV Env derived peptide
分子名称: 9-mer peptide from Envelope glycoprotein gp160, Beta-2-microglobulin, HLA class I histocompatibility antigen, ...
著者Niu, L, Cheng, H, Zhang, S, Tan, S, Zhang, Y, Qi, J, Liu, J, Gao, G.F.
登録日2012-11-27
公開日2013-10-02
実験手法X-RAY DIFFRACTION (2.799 Å)
主引用文献Structural basis for the differential classification of HLA-A*6802 and HLA-A*6801 into the A2 and A3 supertypes
Mol.Immunol., 55, 2013
3FFC
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BU of 3ffc by Molmil
Crystal Structure of CF34 TCR in complex with HLA-B8/FLR
分子名称: Beta-2-microglobulin, CADMIUM ION, CF34 alpha chain, ...
著者Gras, S, Burrows, S.R, Kjer-Nielsen, L, Clements, C.S, Liu, Y.C, Sullivan, L.C, Brooks, A.G, Purcell, A.W, McCluskey, J, Rossjohn, J.
登録日2008-12-03
公開日2009-01-27
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献The shaping of T cell receptor recognition by self-tolerance.
Immunity, 30, 2009
1ZVS
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BU of 1zvs by Molmil
Crystal structure of the first class MHC mamu and Tat-Tl8 complex
分子名称: Beta-2-microglobulin, MHC class I antigen, Tat-Tl8
著者Lou, Z, Chu, F, Gao, G.F, Rao, Z.
登録日2005-06-02
公開日2006-06-13
最終更新日2019-11-06
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献First glimpse of the peptide presentation by rhesus macaque MHC class I: crystal structures of Mamu-A*01 complexed with two immunogenic SIV epitopes and insights into CTL escape.
J Immunol., 178, 2007
7EU2
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BU of 7eu2 by Molmil
Complex structure of HLA0201 with recognizing SARS-CoV-2 epitope S1
分子名称: Beta-2-microglobulin, MHC class I antigen, SARS-CoV-2 T-cell Epitope S1
著者Deng, S, Jin, T.
登録日2021-05-15
公開日2021-08-25
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Profiling CD8 + T cell epitopes of COVID-19 convalescents reveals reduced cellular immune responses to SARS-CoV-2 variants.
Cell Rep, 36, 2021
4RA3
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BU of 4ra3 by Molmil
Crystal structure of dimeric S33C beta-2 microglobulin mutant in complex with Thioflavin (ThT) at 2.8 Angstrom resolution
分子名称: 2-[4-(dimethylamino)phenyl]-3,6-dimethyl-1,3-benzothiazol-3-ium, Beta-2-microglobulin
著者Halabelian, L, Bolognesi, M, Ricagno, S.
登録日2014-09-09
公開日2015-09-09
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献A covalent homodimer probing early oligomers along amyloid aggregation.
Sci Rep, 5, 2015
1QSE
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BU of 1qse by Molmil
STRUCTURE OF HUMAN A6-TCR BOUND TO HLA-A2 COMPLEXED WITH ALTERED HTLV-1 TAX PEPTIDE V7R
分子名称: PROTEIN (MHC class I HLA-A), PROTEIN (beta-2 microglobulin), PROTEIN (human T-Cell receptor), ...
著者Ding, Y.H, Baker, B.M, Garboczi, D.N, Biddison, W.E, Wiley, D.C.
登録日1999-06-21
公開日1999-12-21
最終更新日2021-11-03
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Four A6-TCR/peptide/HLA-A2 structures that generate very different T cell signals are nearly identical.
Immunity, 11, 1999
3D3V
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BU of 3d3v by Molmil
The complex between TCR A6 and human Class I MHC HLA-A2 with the modified HTLV-1 TAX (Y5(3,4-difluoroPhenylalanine)) peptide
分子名称: A6 TCR alpha chain, A6 TCR beta chain, Beta-2-microglobulin, ...
著者Borbulevych, O.Y, Clemens, J.R, Baker, B.M.
登録日2008-05-12
公開日2009-06-16
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Fluorine substitutions in an antigenic peptide selectively modulate T-cell receptor binding in a minimally perturbing manner.
Biochem.J., 423, 2009
1IM9
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BU of 1im9 by Molmil
Crystal structure of the human natural killer cell inhibitory receptor KIR2DL1 bound to its MHC ligand HLA-Cw4
分子名称: Beta-2 microglobulin, HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, CW-4 CW*0401 ALPHA CHAIN, ...
著者Fan, Q.R, Long, E.O, Wiley, D.C.
登録日2001-05-10
公開日2001-05-30
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal structure of the human natural killer cell inhibitory receptor KIR2DL1-HLA-Cw4 complex.
Nat.Immunol., 2, 2001
1QSF
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BU of 1qsf by Molmil
STRUCTURE OF A6-TCR BOUND TO HLA-A2 COMPLEXED WITH ALTERED HTLV-1 TAX PEPTIDE Y8A
分子名称: BETA-2 MICROGLOBULIN, HUMAN T-CELL RECEPTOR, MHC CLASS I HLA-A, ...
著者Ding, Y.H, Baker, B.M, Garboczi, D.N, Biddison, W.E, Wiley, D.C.
登録日1999-06-21
公開日1999-12-21
最終更新日2021-11-03
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Four A6-TCR/peptide/HLA-A2 structures that generate very different T cell signals are nearly identical.
Immunity, 11, 1999
4X6C
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BU of 4x6c by Molmil
CD1a ternary complex with lysophosphatidylcholine and BK6 TCR
分子名称: (4R,7R,18Z)-4,7-dihydroxy-N,N,N-trimethyl-10-oxo-3,5,9-trioxa-4-phosphaheptacos-18-en-1-aminium 4-oxide, 2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-2-microglobulin, ...
著者Birkinshaw, R.W, Rossjohn, J.
登録日2014-12-08
公開日2015-01-28
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献alpha beta T cell antigen receptor recognition of CD1a presenting self lipid ligands.
Nat.Immunol., 16, 2015
1GZP
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CD1b in complex with GM2 ganglioside
分子名称: B2-MICROGLOBULIN, DOCOSANE, DODECANE, ...
著者Gadola, S.D, Zaccai, N.R, Harlos, K, Shepherd, D, Ritter, G, Schmidt, R.R, Jones, E.Y, Cerundolo, V.
登録日2002-05-24
公開日2002-07-31
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structure of human CD1b with bound ligands at 2.3 A, a maze for alkyl chains.
Nat. Immunol., 3, 2002
5W69
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HLA-C*06:02 presenting ARFNDLRFV
分子名称: ALA-ARG-PHE-ASN-ASP-LEU-ARG-PHE-VAL, Beta-2-microglobulin, HLA class I histocompatibility antigen, ...
著者Mobbs, J.I, Vivian, J.P, Rossjohn, J.
登録日2017-06-16
公開日2017-08-23
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献The molecular basis for peptide repertoire selection in the human leucocyte antigen (HLA) C*06:02 molecule.
J. Biol. Chem., 292, 2017
1I7T
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CRYSTAL STRUCTURE OF CLASS I MHC A2 IN COMPLEX WITH PEPTIDE P1049-5V
分子名称: 9 RESIDUE PEPTIDE, BETA-2-MICROGLOBULIN, HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, ...
著者Busslep, J, Zhao, R, Loftus, D, Appella, E, Collins, E.J.
登録日2001-03-10
公開日2001-10-24
最終更新日2021-07-21
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献T cell activity correlates with oligomeric peptide-major histocompatibility complex binding on T cell surface
J.Biol.Chem., 276, 2001
3QDM
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BU of 3qdm by Molmil
The complex between TCR DMF4 and human Class I MHC HLA-A2 with the bound MART-1(26-35)(A27L) decameric peptide
分子名称: Beta-2-microglobulin, DMF4 alpha chain, DMF4 beta chain, ...
著者Borbulevych, O.Y, Baker, B.M.
登録日2011-01-18
公開日2011-07-06
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献TCRs Used in Cancer Gene Therapy Cross-React with MART-1/Melan-A Tumor Antigens via Distinct Mechanisms.
J.Immunol., 187, 2011
3I6K
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BU of 3i6k by Molmil
Newly identified epitope from SARS-CoV membrane protein complexed with HLA-A*0201
分子名称: Beta-2-microglobulin, HLA class I histocompatibility antigen, A-2 alpha chain, ...
著者Liu, J, Sun, Y, Qi, J, Chu, F, Wu, H, Gao, F, Li, T, Yan, J, Gao, G.F.
登録日2009-07-07
公開日2010-06-16
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献The membrane protein of severe acute respiratory syndrome coronavirus acts as a dominant immunogen revealed by a clustering region of novel functionally and structurally defined cytotoxic T-lymphocyte epitopes
J Infect Dis, 202, 2010
4JRY
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BU of 4jry by Molmil
Crystal Structure of SB47 TCR-HLA B*3505-LPEP complex
分子名称: Beta-2-microglobulin, MAGNESIUM ION, MHC class I antigen, ...
著者Liu, Y.C, Rossjohn, J, Gras, S.
登録日2013-03-22
公開日2013-04-10
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Highly divergent T-cell receptor binding modes underlie specific recognition of a bulged viral peptide bound to a human leukocyte antigen class I molecule.
J.Biol.Chem., 288, 2013
8A7Q
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beta-2-microglobulin V27M amyloid fibril form 4PF
分子名称: Beta-2-microglobulin
著者Wilkinson, M, Gallardo, R, Radford, S.E, Ranson, N.A.
登録日2022-06-21
公開日2023-03-22
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Disease-relevant beta 2 -microglobulin variants share a common amyloid fold.
Nat Commun, 14, 2023
1QRN
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BU of 1qrn by Molmil
CRYSTAL STRUCTURE OF HUMAN A6 TCR COMPLEXED WITH HLA-A2 BOUND TO ALTERED HTLV-1 TAX PEPTIDE P6A
分子名称: BETA-2 MICROGLOBULIN, HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, A-2 ALPHA CHAIN, ...
著者Ding, Y.H, Baker, B.M, Garboczi, D.N, Biddison, W.E, Wiley, D.C.
登録日1999-06-14
公開日1999-10-14
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Four A6-TCR/peptide/HLA-A2 structures that generate very different T cell signals are nearly identical.
Immunity, 11, 1999
8BP6
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Structure of MHC-class I related molecule MR1 with bound M3Ade
分子名称: (1R,5S)-8-(9H-purin-6-yl)-2-oxa-8-azabicyclo[3.3.1]nona-3,6-diene-4,6-dicarbaldehyde, Beta-2-microglobulin,Major histocompatibility complex class I-related gene protein
著者Berloffa, G, Jakob, R.P, Maier, T.
登録日2022-11-16
公開日2023-11-29
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献The carbonyl nucleoside adduct M3Ade stabilizes MR1 and activates MR1-restricted self- and tumor-reactive T cells
To Be Published

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件を2024-08-07に公開中

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