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8BP6

Structure of MHC-class I related molecule MR1 with bound M3Ade

Summary for 8BP6
Entry DOI10.2210/pdb8bp6/pdb
DescriptorBeta-2-microglobulin,Major histocompatibility complex class I-related gene protein, (1R,5S)-8-(9H-purin-6-yl)-2-oxa-8-azabicyclo[3.3.1]nona-3,6-diene-4,6-dicarbaldehyde (3 entities in total)
Functional Keywordsmajor histocompatibility complex class i-related gene protein, antigen, immnun system, immune system
Biological sourceHomo sapiens (human)
More
Total number of polymer chains2
Total formula weight89203.51
Authors
Berloffa, G.,Jakob, R.P.,Maier, T. (deposition date: 2022-11-16, release date: 2023-11-29)
Primary citationChancellor, A.,Berloffa, G.,Jakob, R.P.,Maier, T.,de Libero, G.
The carbonyl nucleoside adduct M3Ade stabilizes MR1 and activates MR1-restricted self- and tumor-reactive T cells
To Be Published,
Experimental method
X-RAY DIFFRACTION (2.8 Å)
Structure validation

222415

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