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PDB: 31 件
5IZA
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BU of 5iza by Molmil
Protein-protein interaction
分子名称: ACE-GLY-GLY-GLU-ALA-LEU-ALA-TRP-NH2, Adenomatous polyposis coli protein
著者Zhao, Y, Jiang, H, Yang, X, Jiang, F, Song, K, Zhang, J.
登録日2016-03-25
公開日2017-07-05
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Peptidomimetic inhibitors of APC-Asef interaction block colorectal cancer migration.
Nat. Chem. Biol., 13, 2017
3NMW
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BU of 3nmw by Molmil
Crystal structure of armadillo repeats domain of APC
分子名称: APC variant protein, SULFATE ION
著者Zhang, Z, Chen, L, Gao, L, Lin, K, Wu, G.
登録日2010-06-22
公開日2011-07-06
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structural basis for the recognition of Asef by adenomatous polyposis coli.
Cell Res., 22, 2012
4YK6
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BU of 4yk6 by Molmil
Crystal structure of APC-ARM in complexed with Amer1-A4
分子名称: APC membrane recruitment protein 1, Adenomatous polyposis coli protein
著者Zhang, Z, Xiao, Y, Wu, G.
登録日2015-03-04
公開日2016-03-09
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structures of the APC-ARM domain in complexes with discrete Amer1/WTX fragments reveal that it uses a consensus mode to recognize its binding partners
Cell Discov, 1, 2015
5Z8H
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BU of 5z8h by Molmil
APC with an inhibitor
分子名称: Adenomatous polyposis coli protein, GLYCEROL, Peptide inhibitor
著者Zhang, J, Yang, X.Y, Song, K.
登録日2018-01-31
公開日2019-02-06
実験手法X-RAY DIFFRACTION (1.79 Å)
主引用文献APC with an inhibitor
To Be Published
1EMU
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BU of 1emu by Molmil
STRUCTURE OF THE AXIN RGS-HOMOLOGOUS DOMAIN IN COMPLEX WITH A SAMP REPEAT FROM APC
分子名称: ADENOMATOUS POLYPOSIS COLI PROTEIN, AXIN, GLYCEROL
著者Spink, K.E, Polakis, P, Weis, W.I.
登録日2000-03-17
公開日2000-07-05
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural basis of the Axin-adenomatous polyposis coli interaction.
EMBO J., 19, 2000
4YJE
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BU of 4yje by Molmil
Crystal structure of APC-ARM in complexed with Amer1-A1
分子名称: APC membrane recruitment protein 1, Adenomatous polyposis coli protein
著者Zhang, Z, Xiao, Y, Wu, G.
登録日2015-03-03
公開日2016-03-09
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structures of the APC-ARM domain in complexes with discrete Amer1/WTX fragments reveal that it uses a consensus mode to recognize its binding partners
Cell Discov, 1, 2015
5B6G
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BU of 5b6g by Molmil
Protein-protein interaction
分子名称: Adenomatous polyposis coli protein, GLYCEROL, PHQ-ALA-GLY-GLU-ALA-XYC-TYR-GLU, ...
著者Zhao, Y, Jiang, H, Yang, X, Jiang, F, Song, K, Zhang, J.
登録日2016-05-27
公開日2017-05-31
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.99 Å)
主引用文献Peptidomimetic inhibitors of APC-Asef interaction block colorectal cancer migration.
Nat. Chem. Biol., 13, 2017
4G69
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BU of 4g69 by Molmil
Structure of the Human Discs Large 1 PDZ2 - Adenomatous Polyposis Coli Cytoskeletal Polarity Complex
分子名称: Adenomatous polyposis coli protein, Disks large homolog 1
著者Slep, K.C.
登録日2012-07-18
公開日2012-12-12
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structure of the Human Discs Large 1 PDZ2- Adenomatous Polyposis Coli Cytoskeletal Polarity Complex: Insight into Peptide Engagement and PDZ Clustering.
Plos One, 7, 2012
8X2Q
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BU of 8x2q by Molmil
The Crystal Structure of APC from Biortus.
分子名称: 1,2-ETHANEDIOL, Adenomatous polyposis coli protein
著者Wang, F, Cheng, W, Lv, Z, Ju, C, Bao, C.
登録日2023-11-10
公開日2023-11-22
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献The Crystal Structure of APC from Biortus.
To Be Published
1M5I
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BU of 1m5i by Molmil
Crystal Structure of the coiled coil region 129-250 of the tumor suppressor gene product APC
分子名称: APC protein
著者Tickenbrock, L, Cramer, J, Vetter, I.R, Mueller, O.
登録日2002-07-09
公開日2002-11-20
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献The coiled coil region (amino acids 129-250) of the tumor suppressor protein adenomatous polyposis coli (APC). Its structure and its interaction with chromosome maintenance region 1 (Crm-1).
J.Biol.Chem., 277, 2002
8GSJ
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BU of 8gsj by Molmil
APC-Asef tripeptide inhibitor
分子名称: (1R,2S)-2-phenylcyclopropanamine, 2-methylsulfanylpyrimidine-4-carbaldehyde, Adenomatous polyposis coli protein, ...
著者Zhang, J, Wang, X.F, Song, K.
登録日2022-09-06
公開日2023-12-27
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献APC-Asef tripeptide inhibitor
To Be Published
7XTY
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BU of 7xty by Molmil
Crystal Structure of the second PDZ domain from human PTPN13 in complex with APC peptide
分子名称: APC-peptide, Tyrosine-protein phosphatase non-receptor type 13
著者Jing, L.Q, Sun, X.N, Ma, W.H, Zhou, W.J, Wu, D.L.
登録日2022-05-18
公開日2023-05-17
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Targeting PTPN13 with 11 amino acid peptides of C-terminal APC prevents immune evasion of colorectal cancer
to be published
3AU3
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BU of 3au3 by Molmil
Crystal structure of armadillo repeat domain of APC
分子名称: Adenomatous polyposis coli protein
著者Murayama, K, Kato-Murayama, M, Terada, T, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2011-01-28
公開日2011-11-02
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal structures of the armadillo repeat domain of adenomatous polyposis coli and its complex with the tyrosine-rich domain of sam68
Structure, 19, 2011
4YJL
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BU of 4yjl by Molmil
Crystal structure of APC-ARM in complexed with Amer1-A2
分子名称: 1,2-ETHANEDIOL, APC membrane recruitment protein 1, Adenomatous polyposis coli protein
著者Zhang, Z, Xiao, Y, Wu, G.
登録日2015-03-03
公開日2016-03-09
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structures of the APC-ARM domain in complexes with discrete Amer1/WTX fragments reveal that it uses a consensus mode to recognize its binding partners
Cell Discov, 1, 2015
1V18
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BU of 1v18 by Molmil
The crystal structure of beta-catenin armadillo repeat complexed with a phosphorylated APC 20mer repeat.
分子名称: ADENOMATOUS POLYPOSIS COLI, BETA-CATENIN
著者Ha, N.-C, Weis, W.I.
登録日2004-04-09
公開日2005-01-12
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Mechanism of Phosphorylation-Dependent Binding of Apc to Beta-Catenin and its Role in Beta-Catenin Degradation
Mol.Cell, 15, 2004
1T08
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BU of 1t08 by Molmil
Crystal structure of beta-catenin/ICAT helical domain/unphosphorylated APC R3
分子名称: Adenomatous polyposis coli protein, Beta-catenin, Beta-catenin-interacting protein 1
著者Ha, N.-C, Tonozuka, T, Stamos, J.L, Weis, W.I.
登録日2004-04-07
公開日2004-10-12
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Mechanism of phosphorylation-dependent binding of APC to beta-catenin and its role in beta-catenin degradation
Mol.Cell, 15, 2004
5IZ6
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BU of 5iz6 by Molmil
Protein-protein interaction
分子名称: Adenomatous polyposis coli protein, DI(HYDROXYETHYL)ETHER, PHQ-ALA-GLY-GLU-ALA-LEU-TYR-GLU-NH2, ...
著者Zhao, Y, Jiang, H, Yang, X, Jiang, F, Song, K, Zhang, J.
登録日2016-03-25
公開日2017-07-05
最終更新日2024-04-17
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Peptidomimetic inhibitors of APC-Asef interaction block colorectal cancer migration.
Nat. Chem. Biol., 13, 2017
3RL8
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BU of 3rl8 by Molmil
Crystal structure of hDLG1-PDZ2 complexed with APC
分子名称: 11-mer peptide from Adenomatous polyposis coli protein, Disks large homolog 1
著者Zhang, Z, Li, H, Wu, G.
登録日2011-04-19
公開日2011-12-14
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Molecular basis for the recognition of adenomatous polyposis coli by the Discs Large 1 protein.
Plos One, 6, 2011
3NMX
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BU of 3nmx by Molmil
Crystal structure of APC complexed with Asef
分子名称: APC variant protein, Rho guanine nucleotide exchange factor 4
著者Zhang, Z, Chen, L, Gao, L, Lin, K, Wu, G.
登録日2010-06-22
公開日2011-07-06
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural basis for the recognition of Asef by adenomatous polyposis coli.
Cell Res., 22, 2012
3RL7
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BU of 3rl7 by Molmil
Crystal structure of hDLG1-PDZ1 complexed with APC
分子名称: 11-mer peptide from Adenomatous polyposis coli protein, Disks large homolog 1
著者Zhang, Z, Li, H, Wu, G.
登録日2011-04-19
公開日2011-12-14
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Molecular basis for the recognition of adenomatous polyposis coli by the Discs Large 1 protein.
Plos One, 6, 2011
1DEB
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BU of 1deb by Molmil
CRYSTAL STRUCTURE OF THE N-TERMINAL COILED COIL DOMAIN FROM APC
分子名称: ADENOMATOUS POLYPOSIS COLI PROTEIN, SULFATE ION
著者Day, C.L, Alber, T.
登録日1999-11-14
公開日2000-09-06
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal structure of the amino-terminal coiled-coil domain of the APC tumor suppressor.
J.Mol.Biol., 301, 2000
3QHE
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BU of 3qhe by Molmil
Crystal structure of the complex between the armadillo repeat domain of adenomatous polyposis coli and the tyrosine-rich domain of Sam68
分子名称: Adenomatous polyposis coli protein, KH domain-containing, RNA-binding, ...
著者Morishita, E.C.J, Murayama, K, Kato-Murayama, M, Ishizuku-Katsura, Y, Tomabechi, Y, Terada, T, Handa, N, Shirouzu, M, Akiyama, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2011-01-25
公開日2011-11-02
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal structures of the armadillo repeat domain of adenomatous polyposis coli and its complex with the tyrosine-rich domain of sam68
Structure, 19, 2011
7F6M
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BU of 7f6m by Molmil
Crystal structure of APC complexed with a peptide inhibitor MAI-516
分子名称: Adenomatous polyposis coli protein, DI(HYDROXYETHYL)ETHER, GLYCEROL, ...
著者Song, K, Zhang, J.
登録日2021-06-25
公開日2022-06-29
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Discovery of Efficient Adenomatous Polyposis Coli - Rho Guanine Nucleotide Exchange Factor 4 Inhibitors by Employing High Binding Affinity Tracer
To Be Published
1TH1
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BU of 1th1 by Molmil
Beta-catenin in complex with a phosphorylated APC 20aa repeat fragment
分子名称: Adenomatous polyposis coli protein, Beta-catenin
著者Xing, Y, Clements, W.K, Le Trong, I, Hinds, T.R, Stenkamp, R, Kimelman, D, Xu, W.
登録日2004-05-31
公開日2004-09-07
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal Structure of a beta-Catenin/APC Complex Reveals a Critical Role for APC Phosphorylation in APC Function.
Mol.Cell, 15, 2004
7F7O
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BU of 7f7o by Molmil
APC-Asef FP assay tracer
分子名称: Adenomatous polyposis coli protein, N-[3',6'-bis(oxidanyl)-3-oxidanylidene-spiro[2-benzofuran-1,9'-xanthene]-5-yl]methanethioamide, Tracer 7
著者Yang, X, Zhang, J.
登録日2021-06-30
公開日2022-07-06
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献The tracer of FP assay for screening APC-Asef inhbitors
To Be Published

 

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