7F6M

Crystal structure of APC complexed with a peptide inhibitor MAI-516

Summary for 7F6M

• Entry DOI: 10.2210/pdb7f6m/pdb
• Descriptor: Adenomatous polyposis coli protein, MAI-516 inhibitor, GLYCEROL, ... (6 entities in total)
• Functional Keywords: protein-ptrotein interaction inhibitor, oncoprotein
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 2
• Total formula weight: 40901.80

Authors

Song, K.,Zhang, J. (deposition date: 2021-06-25, release date: 2022-06-29, Last modification date: 2023-11-29)

• Primary citation: Jie, Z.,Zhang, J.; Discovery of Efficient Adenomatous Polyposis Coli - Rho Guanine Nucleotide Exchange Factor 4 Inhibitors by Employing High Binding Affinity Tracer; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.4 Å)