7F6M
Crystal structure of APC complexed with a peptide inhibitor MAI-516
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Adenomatous polyposis coli protein | polymer | 353 | 39137.0 | 1 | UniProt (P25054) Pfam (PF18797) Pfam (PF00514) | Homo sapiens (Human) | Protein APC,Deleted in polyposis 2.5 |
| 2 | B (B) | MAI-516 inhibitor | polymer | 9 | 899.9 | 1 | Homo sapiens | ||
| 3 | C, D, E, I, J (A, B) | GLYCEROL | non-polymer | 92.1 | 5 | Chemie (GOL) | |||
| 4 | F, G (A) | SULFATE ION | non-polymer | 96.1 | 2 | Chemie (SO4) | |||
| 5 | H, K (A, B) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 2 | Chemie (PEG) | |||
| 6 | L, M (A, B) | water | water | 18.0 | 97 | Chemie (HOH) |
Sequence modifications
A: 407 - 751 (UniProt: P25054)
| PDB | External Database | Details |
|---|---|---|
| Gly 399 | - | expression tag |
| His 400 | - | expression tag |
| His 401 | - | expression tag |
| His 402 | - | expression tag |
| His 403 | - | expression tag |
| His 404 | - | expression tag |
| His 405 | - | expression tag |
| Met 406 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 40037.0 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 864.8 | |
| All* | Total formula weight | 40901.8 |
