7F6M
Crystal structure of APC complexed with a peptide inhibitor MAI-516
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Adenomatous polyposis coli protein | polymer | 353 | 39137.0 | 1 | UniProt (P25054) Pfam (PF18797) Pfam (PF00514) In PDB | Homo sapiens (Human) | Protein APC,Deleted in polyposis 2.5 |
2 | B | MAI-516 inhibitor | polymer | 9 | 899.9 | 1 | Homo sapiens | ||
3 | A, B | GLYCEROL | non-polymer | 92.1 | 5 | Chemie (GOL) | |||
4 | A | SULFATE ION | non-polymer | 96.1 | 2 | Chemie (SO4) | |||
5 | A, B | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 2 | Chemie (PEG) | |||
6 | water | water | 18.0 | 97 | Chemie (HOH) |
Sequence modifications
A: 407 - 751 (UniProt: P25054)
PDB | External Database | Details |
---|---|---|
Gly 399 | - | expression tag |
His 400 | - | expression tag |
His 401 | - | expression tag |
His 402 | - | expression tag |
His 403 | - | expression tag |
His 404 | - | expression tag |
His 405 | - | expression tag |
Met 406 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 40037.0 | |
Non-Polymers* | Number of molecules | 9 |
Total formula weight | 864.8 | |
All* | Total formula weight | 40901.8 |