1M5I
Crystal Structure of the coiled coil region 129-250 of the tumor suppressor gene product APC
Summary for 1M5I
| Entry DOI | 10.2210/pdb1m5i/pdb |
| Descriptor | APC protein (2 entities in total) |
| Functional Keywords | coiled-coil, antitumor protein |
| Biological source | Homo sapiens (human) |
| Cellular location | Cell junction, adherens junction: P25054 |
| Total number of polymer chains | 1 |
| Total formula weight | 14952.78 |
| Authors | Tickenbrock, L.,Cramer, J.,Vetter, I.R.,Mueller, O. (deposition date: 2002-07-09, release date: 2002-11-20, Last modification date: 2024-03-13) |
| Primary citation | Tickenbrock, L.,Cramer, J.,Vetter, I.R.,Muller, O. The coiled coil region (amino acids 129-250) of the tumor suppressor protein adenomatous polyposis coli (APC). Its structure and its interaction with chromosome maintenance region 1 (Crm-1). J.Biol.Chem., 277:32332-32338, 2002 Cited by PubMed: 12070164DOI: 10.1074/jbc.M203990200 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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