7XTY
Crystal Structure of the second PDZ domain from human PTPN13 in complex with APC peptide
Summary for 7XTY
Entry DOI | 10.2210/pdb7xty/pdb |
Descriptor | Tyrosine-protein phosphatase non-receptor type 13, APC-peptide (3 entities in total) |
Functional Keywords | protein-protein complex, peptide binding protein |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 4 |
Total formula weight | 22260.95 |
Authors | Jing, L.Q.,Sun, X.N.,Ma, W.H.,Zhou, W.J.,Wu, D.L. (deposition date: 2022-05-18, release date: 2023-05-17, Last modification date: 2023-11-29) |
Primary citation | Jing, L.Q.,Sun, X.N.,Ma, W.H.,Zhou, W.J.,Wu, D.L. Targeting PTPN13 with 11 amino acid peptides of C-terminal APC prevents immune evasion of colorectal cancer to be published, |
Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
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