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7XTY

Crystal Structure of the second PDZ domain from human PTPN13 in complex with APC peptide

Summary for 7XTY
Entry DOI10.2210/pdb7xty/pdb
DescriptorTyrosine-protein phosphatase non-receptor type 13, APC-peptide (3 entities in total)
Functional Keywordsprotein-protein complex, peptide binding protein
Biological sourceHomo sapiens (human)
More
Total number of polymer chains4
Total formula weight22260.95
Authors
Jing, L.Q.,Sun, X.N.,Ma, W.H.,Zhou, W.J.,Wu, D.L. (deposition date: 2022-05-18, release date: 2023-05-17, Last modification date: 2023-11-29)
Primary citationJing, L.Q.,Sun, X.N.,Ma, W.H.,Zhou, W.J.,Wu, D.L.
Targeting PTPN13 with 11 amino acid peptides of C-terminal APC prevents immune evasion of colorectal cancer
to be published,
Experimental method
X-RAY DIFFRACTION (2.1 Å)
Structure validation

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