4OZC
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![BU of 4ozc by Molmil](/molmil-images/mine/4ozc) | Backbone Modifications in the Protein GB1 Helix and Loops: beta-ACPC21, beta-ACPC24, beta-3-Lys28, beta-3-Lys31, beta-ACPC35, beta-ACPC40 | 分子名称: | GLYCEROL, SULFATE ION, Streptococcal Protein GB1 Backbone Modified Variant: beta-ACPC21, ... | 著者 | Reinert, Z.E, Horne, W.S. | 登録日 | 2014-02-14 | 公開日 | 2014-07-16 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.301 Å) | 主引用文献 | Folding Thermodynamics of Protein-Like Oligomers with Heterogeneous Backbones. Chem Sci, 5, 2014
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7DA8
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![BU of 7da8 by Molmil](/molmil-images/mine/7da8) | |
2FLP
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![BU of 2flp by Molmil](/molmil-images/mine/2flp) | Binary complex of the catalytic core of human DNA polymerase iota with DNA (template G) | 分子名称: | DNA polymerase iota, DNA primer strand, DNA template strand | 著者 | Nair, D.T, Johnson, R.E, Prakash, L, Prakash, S, Aggarwal, A.K. | 登録日 | 2006-01-06 | 公開日 | 2006-12-05 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | An incoming nucleotide imposes an anti to syn conformational change on the templating purine in the human DNA polymerase-iota active site. Structure, 14, 2006
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3Q8R
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![BU of 3q8r by Molmil](/molmil-images/mine/3q8r) | Human DNA polymerase iota incorporating dGTP opposite 8-oxo-guanine | 分子名称: | 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DNA (5'-D(*TP*CP*AP*(8OG)P*GP*GP*GP*TP*CP*CP*T)-3'), DNA (5'-D(P*AP*GP*GP*AP*CP*CP*C)-3'), ... | 著者 | Kirouac, K.N, Ling, H. | 登録日 | 2011-01-06 | 公開日 | 2011-02-23 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | 主引用文献 | Unique active site promotes error-free replication opposite an 8-oxo-guanine lesion by human DNA polymerase iota. Proc.Natl.Acad.Sci.USA, 108, 2011
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6O41
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![BU of 6o41 by Molmil](/molmil-images/mine/6o41) | |
5KT2
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![BU of 5kt2 by Molmil](/molmil-images/mine/5kt2) | Teranry complex of human DNA polymerase iota(26-445) inserting dCMPNPP opposite template G in the presence of Mg2+ | 分子名称: | 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]cytidine, DNA (5'-D(*CP*TP*GP*GP*GP*GP*TP*CP*CP*T)-3'), DNA (5'-D(P*AP*GP*GP*AP*CP*CP*C)-3'), ... | 著者 | Choi, J.Y, Patra, A, Yeom, M, Lee, Y.S, Zhang, Q, Egli, M, Guengerich, F.P. | 登録日 | 2016-07-11 | 公開日 | 2016-08-31 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (2.488 Å) | 主引用文献 | Kinetic and Structural Impact of Metal Ions and Genetic Variations on Human DNA Polymerase iota. J.Biol.Chem., 291, 2016
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4FS1
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![BU of 4fs1 by Molmil](/molmil-images/mine/4fs1) | |
5BMI
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![BU of 5bmi by Molmil](/molmil-images/mine/5bmi) | Nitroxide Spin Labels in Protein GB1: T44 Mutant, Crystal Form A | 分子名称: | Immunoglobulin G-binding protein G, S-[(1-oxyl-2,2,5,5-tetramethyl-2,5-dihydro-1H-pyrrol-3-yl)methyl] methanesulfonothioate | 著者 | Cunningham, T.C, Horne, W.S, Saxena, S. | 登録日 | 2015-05-22 | 公開日 | 2016-04-06 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Rotameric preferences of a protein spin label at edge-strand beta-sheet sites. Protein Sci., 25, 2016
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3EPG
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![BU of 3epg by Molmil](/molmil-images/mine/3epg) | |
2FLN
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![BU of 2fln by Molmil](/molmil-images/mine/2fln) | binary complex of catalytic core of human DNA polymerase iota with DNA (template A) | 分子名称: | DNA polymerase iota, DNA primer strand, DNA template strand | 著者 | Nair, D.T, Johnson, R.E, Prakash, L, Prakash, S, Aggarwal, A.K. | 登録日 | 2006-01-06 | 公開日 | 2006-12-05 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | An incoming nucleotide imposes an anti to syn conformational change on the templating purine in the human DNA polymerase-iota active site. Structure, 14, 2006
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2ALZ
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![BU of 2alz by Molmil](/molmil-images/mine/2alz) | Ternary Complex of hPoli with DNA and dCTP | 分子名称: | 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, 5'-D(*AP*GP*GP*AP*CP*CP*(DOC))-3', 5'-D(*TP*GP*GP*GP*GP*TP*CP*CP*T)-3', ... | 著者 | Nair, D.T, Johnson, R.E, Prakash, L, Prakash, S, Aggarwal, A.K. | 登録日 | 2005-08-08 | 公開日 | 2005-10-25 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Human DNA Polymerase iota Incorporates dCTP Opposite Template G via a G.C+ Hoogsteen Base Pair. Structure, 13, 2005
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4EBD
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![BU of 4ebd by Molmil](/molmil-images/mine/4ebd) | Conformationally Restrained North-methanocarba-2'-deoxyadenosine Corrects the Error-Prone Nature of Human DNA Polymerase Iota | 分子名称: | 5'-D(P*AP*GP*GP*AP*CP*CP*(DOC))-3', 5'-D(P*CP*TP*GP*GP*GP*TP*CP*CP*T)-3', CALCIUM ION, ... | 著者 | Eoff, R.L, Ketkar, A, Banerjee, S. | 登録日 | 2012-03-23 | 公開日 | 2012-06-13 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.571 Å) | 主引用文献 | A Nucleotide-Analogue-Induced Gain of Function Corrects the Error-Prone Nature of Human DNA Polymerase iota. J.Am.Chem.Soc., 134, 2012
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2FLL
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![BU of 2fll by Molmil](/molmil-images/mine/2fll) | Ternary complex of human DNA polymerase iota with DNA and dTTP | 分子名称: | DNA polymerase iota, DNA primer strand, DNA template strand, ... | 著者 | Nair, D.T, Johnson, R.E, Prakash, L, Prakash, S, Aggarwal, A.K. | 登録日 | 2006-01-06 | 公開日 | 2006-12-12 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | An incoming nucleotide imposes an anti to syn conformational change on the templating purine in the human DNA polymerase-iota active site. Structure, 14, 2006
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6U8C
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![BU of 6u8c by Molmil](/molmil-images/mine/6u8c) | Crystal structure of an engineered ultra-high affinity Fab-Protein G complex | 分子名称: | Antibody heavy chain Fab, Antibody light chain Fab, Protein G | 著者 | Slezak, T, Filippova, E.V, Davydova, E.K, Kossiakoff, A.A. | 登録日 | 2019-09-04 | 公開日 | 2019-10-23 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.61 Å) | 主引用文献 | An engineered ultra-high affinity Fab-Protein G pair enables a modular antibody platform with multifunctional capability. Protein Sci., 29, 2020
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5ULW
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![BU of 5ulw by Molmil](/molmil-images/mine/5ulw) | |
5KT3
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![BU of 5kt3 by Molmil](/molmil-images/mine/5kt3) | Teranry complex of human DNA polymerase iota(26-445) inserting dCMPNPP opposite template G in the presence of Mn2+ | 分子名称: | 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]cytidine, DNA (5'-D(*CP*TP*GP*GP*GP*GP*TP*CP*CP*T)-3'), DNA (5'-D(P*AP*GP*GP*AP*CP*CP*C)-3'), ... | 著者 | Choi, J.Y, Patra, A, Yeom, M, Lee, Y.S, Zhang, Q, Egli, M, Guengerich, F.P. | 登録日 | 2016-07-11 | 公開日 | 2016-08-31 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (2.64 Å) | 主引用文献 | Kinetic and Structural Impact of Metal Ions and Genetic Variations on Human DNA Polymerase iota. J.Biol.Chem., 291, 2016
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6UUH
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![BU of 6uuh by Molmil](/molmil-images/mine/6uuh) | |
5KT4
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![BU of 5kt4 by Molmil](/molmil-images/mine/5kt4) | Teranry complex of human DNA polymerase iota R96G inserting dCMPNPP opposite template G in the presence of Mg2+ | 分子名称: | 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]cytidine, DNA (5'-D(*CP*TP*GP*GP*GP*GP*TP*CP*CP*T)-3'), DNA (5'-D(P*AP*GP*GP*AP*CP*CP*C)-3'), ... | 著者 | Choi, J.Y, Patra, A, Yeom, M, Lee, Y.S, Zhang, Q, Egli, M, Guengerich, F.P. | 登録日 | 2016-07-11 | 公開日 | 2016-08-31 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (2.78 Å) | 主引用文献 | Kinetic and Structural Impact of Metal Ions and Genetic Variations on Human DNA Polymerase iota. J.Biol.Chem., 291, 2016
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5KT5
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![BU of 5kt5 by Molmil](/molmil-images/mine/5kt5) | Teranry complex of human DNA polymerase iota R96G inserting dCMPNPP opposite template G in the presence of Mn2+ | 分子名称: | 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]cytidine, DNA (5'-D(*CP*TP*GP*GP*GP*GP*TP*CP*CP*T)-3'), DNA (5'-D(P*AP*GP*GP*AP*CP*CP*C)-3'), ... | 著者 | Choi, J.Y, Patra, A, Yeom, M, Lee, Y.S, Zhang, Q, Egli, M, Guengerich, F.P. | 登録日 | 2016-07-11 | 公開日 | 2016-08-31 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (2.798 Å) | 主引用文献 | Kinetic and Structural Impact of Metal Ions and Genetic Variations on Human DNA Polymerase iota. J.Biol.Chem., 291, 2016
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3UI3
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![BU of 3ui3 by Molmil](/molmil-images/mine/3ui3) | |
3NGD
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![BU of 3ngd by Molmil](/molmil-images/mine/3ngd) | |
3H4B
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![BU of 3h4b by Molmil](/molmil-images/mine/3h4b) | Ternary complex of human DNA polymerase iota with template U/T and incoming dATP | 分子名称: | 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, 5'-D(*AP*GP*GP*AP*CP*CP*(DOC))-3', 5'-D(*TP*(BRU)P*GP*GP*GP*TP*CP*CP*T)-3', ... | 著者 | Jain, R, Nair, D.T, Johnson, R.E, Prakash, L, Prakash, S, Aggarwal, A.K. | 登録日 | 2009-04-18 | 公開日 | 2009-07-21 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | 主引用文献 | Replication across template T/U by human DNA polymerase-iota. Structure, 17, 2009
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4EYH
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![BU of 4eyh by Molmil](/molmil-images/mine/4eyh) | |
4EYI
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![BU of 4eyi by Molmil](/molmil-images/mine/4eyi) | |
3EPI
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![BU of 3epi by Molmil](/molmil-images/mine/3epi) | |