5KT3

Teranry complex of human DNA polymerase iota(26-445) inserting dCMPNPP opposite template G in the presence of Mn2+

Summary for 5KT3

• Entry DOI: 10.2210/pdb5kt3/pdb
• Related: 5KT2 5KT4 5KT5 5KT6 5KT7
• Descriptor: DNA (5'-D(*CP*TP*GP*GP*GP*GP*TP*CP*CP*T)-3'), DNA (5'-D(P*AP*GP*GP*AP*CP*CP*C)-3'), DNA polymerase iota, ... (6 entities in total)
• Functional Keywords: dna polymerase, poli, manganese, transferase
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 3
• Total formula weight: 52817.73

Authors

Choi, J.Y.,Patra, A.,Yeom, M.,Lee, Y.S.,Zhang, Q.,Egli, M.,Guengerich, F.P. (deposition date: 2016-07-11, release date: 2016-08-31, Last modification date: 2024-03-06)

• Primary citation: Choi, J.Y.,Patra, A.,Yeom, M.,Lee, Y.S.,Zhang, Q.,Egli, M.,Guengerich, F.P.; Kinetic and Structural Impact of Metal Ions and Genetic Variations on Human DNA Polymerase iota.; J.Biol.Chem., 291:21063-21073, 2016; PubMed: 27555320; DOI: 10.1074/jbc.M116.748285

Experimental method

X-RAY DIFFRACTION (2.64 Å)