5KT3

Teranry complex of human DNA polymerase iota(26-445) inserting dCMPNPP opposite template G in the presence of Mn2+

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003684	molecular_function	damaged DNA binding
A	0003887	molecular_function	DNA-directed DNA polymerase activity
A	0006281	biological_process	DNA repair

Functional Information from PDB Data

site_id	AC1
Number of Residues	22
Details	binding site for residue 0KX A 501

Chain	Residue
A	ASP59
A	ARG96
A	LYS102
A	ASP151
A	LYS239
A	MN502
A	MN503
A	HOH614
A	HOH620
A	HOH638
A	HOH644
A	LEU60
P	DC873
T	DG840
T	DG841
A	ASP61
A	CYS62
A	PHE63
A	TYR64
A	VAL89
A	THR90
A	TYR93

---

site_id	AC2
Number of Residues	5
Details	binding site for residue MN A 502

Chain	Residue
A	ASP59
A	LEU60
A	ASP151
A	0KX501
A	MN503

---

site_id	AC3
Number of Residues	6
Details	binding site for residue MN A 503

Chain	Residue
A	ASP59
A	ASP151
A	GLU152
A	0KX501
A	MN502
P	DC873

---

site_id	AC4
Number of Residues	4
Details	binding site for residue MN A 504

Chain	Residue
A	LYS262
A	ILE264
A	ILE267
P	DC872

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	213
Details	Domain: {"description":"UmuC","evidences":[{"source":"PROSITE-ProRule","id":"PRU00216","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	65
Details	Region: {"description":"DNA-binding","evidences":[{"source":"PubMed","id":"15254543","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"27555320","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1T3N","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5KT2","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5KT4","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5KT6","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	1
Details	Active site: {"description":"Proton acceptor","evidences":[{"source":"PROSITE-ProRule","id":"PRU00216","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	3
Details	Binding site: {"evidences":[{"source":"PubMed","id":"27555320","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5KT5","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	2
Details	Binding site: {"evidences":[{"source":"PubMed","id":"15254543","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1T3N","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---