6U8C

Crystal structure of an engineered ultra-high affinity Fab-Protein G complex

Summary for 6U8C

• Entry DOI: 10.2210/pdb6u8c/pdb
• Descriptor: Protein G, Antibody light chain Fab, Antibody heavy chain Fab, ... (4 entities in total)
• Functional Keywords: engineered fab, protein g, high affinity, immune system
• Biological source: Streptococcus sp. 'group G'; More
• Total number of polymer chains: 6
• Total formula weight: 112044.48

Authors

Slezak, T.,Filippova, E.V.,Davydova, E.K.,Kossiakoff, A.A. (deposition date: 2019-09-04, release date: 2019-10-23, Last modification date: 2023-10-11)

• Primary citation: Slezak, T.,Bailey, L.J.,Jaskolowski, M.,Nahotko, D.A.,Filippova, E.V.,Davydova, E.K.,Kossiakoff, A.A.; An engineered ultra-high affinity Fab-Protein G pair enables a modular antibody platform with multifunctional capability.; Protein Sci., 29:141-156, 2020; PubMed: 31622515; DOI: 10.1002/pro.3751

Experimental method

X-RAY DIFFRACTION (2.61 Å)