5KT5

Teranry complex of human DNA polymerase iota R96G inserting dCMPNPP opposite template G in the presence of Mn2+

Summary for 5KT5

Related5KT2 5KT3 5KT4 5KT6 5KT7
DescriptorDNA (5'-D(*CP*TP*GP*GP*GP*GP*TP*CP*CP*T)-3'), DNA (5'-D(P*AP*GP*GP*AP*CP*CP*C)-3'), DNA polymerase iota, ... (6 entities in total)
Functional Keywordsdna polymerase, poli, r96g, manganese, transferase
Biological sourceHomo sapiens (Human)
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Cellular locationNucleus  Q9UNA4
Total number of polymer chains3
Total molecular weight55353.33
Authors
Choi, J.Y.,Patra, A.,Yeom, M.,Lee, Y.S.,Zhang, Q.,Egli, M.,Guengerich, F.P. (deposition date: 2016-07-11, release date: 2016-08-31, Last modification date: 2017-09-13)
Primary citation
Choi, J.Y.,Patra, A.,Yeom, M.,Lee, Y.S.,Zhang, Q.,Egli, M.,Guengerich, F.P.
Kinetic and Structural Impact of Metal Ions and Genetic Variations on Human DNA Polymerase iota.
J.Biol.Chem., 291:21063-21073, 2016
PubMed: 27555320 (PDB entries with the same primary citation)
DOI: 10.1074/jbc.M116.748285
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.798 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.267602.8%8.1%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

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