5KT5
Teranry complex of human DNA polymerase iota R96G inserting dCMPNPP opposite template G in the presence of Mn2+
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | T | DNA (5'-D(*CP*TP*GP*GP*GP*GP*TP*CP*CP*T)-3') | polymer | 10 | 3052.0 | 1 | synthetic construct | ||
| 2 | P | DNA (5'-D(P*AP*GP*GP*AP*CP*CP*C)-3') | polymer | 7 | 2107.4 | 1 | synthetic construct | ||
| 3 | A | DNA polymerase iota | polymer | 445 | 49617.9 | 1 | UniProt (Q9UNA4) Pfam (PF00817) Pfam (PF11799) In PDB | Homo sapiens (Human) | Eta2,RAD30 homolog B |
| 4 | P, A | MANGANESE (II) ION | non-polymer | 54.9 | 2 | Chemie (MN) | |||
| 5 | A | 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]cytidine | non-polymer | 466.2 | 1 | Chemie (0KX) | |||
| 6 | water | water | 18.0 | 10 | Chemie (HOH) |
Sequence modifications
A: 1 - 445 (UniProt: Q9UNA4)
| PDB | External Database | Details |
|---|---|---|
| Gly 96 | Arg 96 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 54777.3 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 576.0 | |
| All* | Total formula weight | 55353.3 |
