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PDB: 534 件

7QO5
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26S proteasome Rpt1-RK -Ubp6-UbVS complex in the si state
分子名称: 26S proteasome complex subunit SEM1, 26S proteasome regulatory subunit 4 homolog, 26S proteasome regulatory subunit 6A, ...
著者Hung, K.Y.S, Klumpe, S, Eisele, M.R, Elsasser, S, Geng, T.T, Cheng, T.C, Joshi, T, Rudack, T, Sakata, E, Finley, D.
登録日2021-12-23
公開日2022-03-16
最終更新日2023-03-15
実験手法ELECTRON MICROSCOPY (6 Å)
主引用文献Allosteric control of Ubp6 and the proteasome via a bidirectional switch.
Nat Commun, 13, 2022
5L9T
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Model of human Anaphase-promoting complex/Cyclosome (APC/C-CDH1) with E2 UBE2S poised for polyubiquitination where UBE2S, APC2, and APC11 are modeled into low resolution density
分子名称: Anaphase-promoting complex subunit 1, Anaphase-promoting complex subunit 10, Anaphase-promoting complex subunit 11, ...
著者Brown, N.G, VanderLinden, R, Dube, P, Haselbach, D, Peters, J.M, Stark, H, Schulman, B.A.
登録日2016-06-11
公開日2016-10-26
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (6.4 Å)
主引用文献Dual RING E3 Architectures Regulate Multiubiquitination and Ubiquitin Chain Elongation by APC/C.
Cell, 165, 2016
6JMA
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cryo-EM structure of DOT1L bound to H2B ubiquitinated nucleosome
分子名称: DNA I&J, Histone H2A, Histone H2B 1.1, ...
著者Jang, S, Song, J.J.
登録日2019-03-07
公開日2019-05-15
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (6.8 Å)
主引用文献Structural basis of recognition and destabilization of the histone H2B ubiquitinated nucleosome by the DOT1L histone H3 Lys79 methyltransferase.
Genes Dev., 33, 2019
7QO4
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BU of 7qo4 by Molmil
26S proteasome WT-Ubp6-UbVS complex in the si state (ATPases, Rpn1, Ubp6, and UbVS)
分子名称: 26S proteasome regulatory subunit RPN1, ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ...
著者Hung, K.Y.S, Klumpe, S, Eisele, M.R, Elsasser, S, Geng, T.T, Cheng, C, Joshi, T, Rudack, T, Sakata, E, Finley, D.
登録日2021-12-23
公開日2022-06-01
実験手法ELECTRON MICROSCOPY (7 Å)
主引用文献Allosteric control of Ubp6 and the proteasome via a bidirectional switch.
Nat Commun, 13, 2022
4WHV
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BU of 4whv by Molmil
E3 ubiquitin-protein ligase RNF8 in complex with Ubiquitin-conjugating enzyme E2 N and Polyubiquitin-B
分子名称: E3 ubiquitin-protein ligase RNF8, Polyubiquitin-B, Ubiquitin-conjugating enzyme E2 N, ...
著者Hodge, C.D, Edwards, R.A, Glover, J.N.M.
登録日2014-09-23
公開日2015-09-30
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (8.3 Å)
主引用文献RNF8 E3 Ubiquitin Ligase Stimulates Ubc13 E2 Conjugating Activity That Is Essential for DNA Double Strand Break Signaling and BRCA1 Tumor Suppressor Recruitment.
J.Biol.Chem., 291, 2016
5A5B
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BU of 5a5b by Molmil
Structure of the 26S proteasome-Ubp6 complex
分子名称: 26S PROTEASE REGULATORY SUBUNIT 4 HOMOLOG, 26S PROTEASE REGULATORY SUBUNIT 6A, 26S PROTEASE REGULATORY SUBUNIT 6B HOMOLOG, ...
著者Aufderheide, A, Beck, F, Stengel, F, Hartwig, M, Schweitzer, A, Pfeifer, G, Goldberg, A.L, Sakata, E, Baumeister, W, Foerster, F.
登録日2015-06-17
公開日2015-07-22
最終更新日2017-08-30
実験手法ELECTRON MICROSCOPY (9.5 Å)
主引用文献Structural Characterization of the Interaction of Ubp6 with the 26S Proteasome.
Proc.Natl.Acad.Sci.USA, 112, 2015
6TBM
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BU of 6tbm by Molmil
Structure of SAGA bound to TBP, including Spt8 and DUB
分子名称: Polyubiquitin-B, SAGA-associated factor 11, Spt20, ...
著者Papai, G, Frechard, A, Kolesnikova, O, Crucifix, C, Schultz, P, Ben-Shem, A.
登録日2019-11-01
公開日2020-02-12
最終更新日2021-06-30
実験手法ELECTRON MICROSCOPY (20 Å)
主引用文献Structure of SAGA and mechanism of TBP deposition on gene promoters.
Nature, 577, 2020
5VEY
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BU of 5vey by Molmil
Solution NMR structure of histone H2A-H2B mono-ubiquitylated at H2A Lys15 in complex with RNF169 (653-708)
分子名称: E3 ubiquitin-protein ligase RNF169, Histone H2B type 1-J,Histone H2A type 1-B/E, Polyubiquitin-B
著者Hu, Q, Botuyan, M.V, Cui, G, Mer, G.
登録日2017-04-06
公開日2017-05-17
最終更新日2022-02-23
実験手法SOLUTION NMR
主引用文献Mechanisms of Ubiquitin-Nucleosome Recognition and Regulation of 53BP1 Chromatin Recruitment by RNF168/169 and RAD18.
Mol. Cell, 66, 2017
5ZD0
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BU of 5zd0 by Molmil
Solution structure of human ubiquitin with three alanine mutations in living eukaryotic cells by in-cell NMR spectroscopy
分子名称: ubiquitin
著者Tanaka, T, Ikeya, T, Kamoshida, H, Mishima, M, Shirakawa, M, Guentert, P, Ito, Y.
登録日2018-02-22
公開日2019-08-21
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献High-Resolution Protein 3D Structure Determination in Living Eukaryotic Cells.
Angew.Chem.Int.Ed.Engl., 58, 2019
6QF8
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BU of 6qf8 by Molmil
Solution NMR ensemble for human ubiquitin at 298K compiled using the CoMAND method
分子名称: Polyubiquitin-B
著者ElGamacy, M, Truffault, V, Zhu, H, Coles, M.
登録日2019-01-09
公開日2019-04-10
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Mapping Local Conformational Landscapes of Proteins in Solution.
Structure, 27, 2019
2K25
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BU of 2k25 by Molmil
Automated NMR Structure of the UBB by FAPSY
分子名称: UBB
著者Lee, W, Jung, J, Lee, W.
登録日2008-03-24
公開日2008-09-30
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献The Automated Suite for Protein Structure by NMR Spectroscopy
To be Published
6K4I
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BU of 6k4i by Molmil
The partially disordered conformation of ubiquitin (Q41N variant)
分子名称: ubiquitin
著者Wakamoto, T, Ikeya, T, Kitazawa, S, Baxter, N.J, Williamson, M.P, Kitahara, R.
登録日2019-05-24
公開日2019-10-30
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Paramagnetic relaxation enhancement-assisted structural characterization of a partially disordered conformation of ubiquitin.
Protein Sci., 28, 2019
2LVO
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BU of 2lvo by Molmil
Structure of the gp78CUE domain bound to monubiquitin
分子名称: E3 ubiquitin-protein ligase AMFR, Ubiquitin
著者Liu, S, Chen, Y, Huang, T, Tarasov, S.G, King, A, Li, J, Weissman, A.M, Byrd, R.A, Das, R.
登録日2012-07-09
公開日2012-11-21
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Promiscuous Interactions of gp78 E3 Ligase CUE Domain with Polyubiquitin Chains.
Structure, 20, 2012
5XBO
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BU of 5xbo by Molmil
Lanthanoid tagging via an unnatural amino acid for protein structure characterization
分子名称: Polyubiquitin-B, TERBIUM(III) ION, UV excision repair protein RAD23 homolog A
著者Jiang, W, Gu, X, Dong, X, Tang, C.
登録日2017-03-21
公開日2017-05-31
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Lanthanoid tagging via an unnatural amino acid for protein structure characterization
J. Biomol. NMR, 67, 2017
2JRI
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BU of 2jri by Molmil
Solution structure of the Josephin domain of Ataxin-3 in complex with ubiquitin molecule.
分子名称: Ataxin-3, UBC protein
著者Nicastro, G, Masino, L, Esposito, V, Menon, R, Pastore, A.
登録日2007-06-27
公開日2008-07-01
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Understanding the plasticity of the ubiquitin-protein recognition code: the josephin domain of ataxin-3 is a diubiquitin binding motif
To be Published
2MBO
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BU of 2mbo by Molmil
K11-linked Diubiquitin average solution structure at pH 6.8, 0 mM NaCl
分子名称: Ubiquitin
著者Castaneda, C.A, Fushman, D.
登録日2013-08-02
公開日2013-09-04
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Unique structural, dynamical, and functional properties of k11-linked polyubiquitin chains.
Structure, 21, 2013
2Z59
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BU of 2z59 by Molmil
Complex Structures of Mouse Rpn13 (22-130aa) and ubiquitin
分子名称: Protein ADRM1, Ubiquitin
著者Chen, X, Schreiner, P, Groll, M, Walters, K.J.
登録日2007-07-01
公開日2008-05-20
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Ubiquitin docking at the proteasome through a novel pleckstrin-homology domain interaction.
Nature, 453, 2008
2MBQ
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BU of 2mbq by Molmil
K11-linked Diubiquitin average solution structure at pH 6.8, 150 mM NaCl
分子名称: Ubiquitin
著者Castaneda, C.A, Fushman, D.
登録日2013-08-03
公開日2013-09-04
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Unique structural, dynamical, and functional properties of k11-linked polyubiquitin chains.
Structure, 21, 2013
6KOW
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BU of 6kow by Molmil
Retracted state of S65/T66 double-phosphorylated ubiquitin
分子名称: Polyubiquitin-B
著者Dong, X, Tang, C.
登録日2019-08-13
公開日2019-08-28
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Ubiquitin is double-phosphorylated by PINK1 for enhanced pH-sensitivity of conformational switch.
Protein Cell, 10, 2019
2LZ6
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BU of 2lz6 by Molmil
Distinct ubiquitin binding modes exhibited by sh3 domains: molecular determinants and functional implications
分子名称: CD2-associated protein, Ubiquitin
著者Ortega-Roldan, J, Azuaga, A, Blackledge, M, Van Nuland, N.
登録日2012-09-24
公開日2013-10-02
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Distinct Ubiquitin Binding Modes Exhibited by SH3 Domains: Molecular Determinants and Functional Implications.
Plos One, 8, 2013
1UD7
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BU of 1ud7 by Molmil
SOLUTION STRUCTURE OF THE DESIGNED HYDROPHOBIC CORE MUTANT OF UBIQUITIN, 1D7
分子名称: PROTEIN (UBIQUITIN CORE MUTANT 1D7)
著者Johnson, E.C, Lazar, G.A, Desjarlais, J.R, Handel, T.M.
登録日1999-04-07
公開日1999-05-06
最終更新日2023-12-27
実験手法SOLUTION NMR
主引用文献Solution structure and dynamics of a designed hydrophobic core variant of ubiquitin.
Structure Fold.Des., 7, 1999
5XK4
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BU of 5xk4 by Molmil
Retracted state of S65-phosphorylated ubiquitin
分子名称: Polyubiquitin-B
著者Dong, X, Gong, Z, Qin, L.Y, Ran, M.L, Zhang, C.L, Liu, K, Liu, Z, Zhang, W.P, Tang, C.
登録日2017-05-05
公開日2017-06-28
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Ubiquitin S65 phosphorylation engenders a pH-sensitive conformational switch
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5XK5
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BU of 5xk5 by Molmil
Relaxed state of S65-phosphorylated ubiquitin
分子名称: Polyubiquitin-B
著者Xu, D, Zhou, G, Qin, L.Y, Ran, M.L, Zhang, C.L, Liu, K, Liu, Z, Zhang, W.P, Tang, C.
登録日2017-05-05
公開日2017-06-28
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Ubiquitin S65 phosphorylation engenders a pH-sensitive conformational switch
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
6KOX
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BU of 6kox by Molmil
Relaxed state of S65/T66 double-phosphorylated ubiquitin
分子名称: Polyubiquitin-B
著者Dong, X, Tang, C.
登録日2019-08-13
公開日2019-08-28
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Ubiquitin is double-phosphorylated by PINK1 for enhanced pH-sensitivity of conformational switch.
Protein Cell, 10, 2019
2RR9
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BU of 2rr9 by Molmil
The solution structure of the K63-Ub2:tUIMs complex
分子名称: Putative uncharacterized protein UIMC1, ubiquitin
著者Sekiyama, N, Jee, J, Isogai, S, Akagi, K, Huang, T, Ariyoshi, M, Tochio, H, Shirakawa, M.
登録日2010-06-16
公開日2011-07-06
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献The solution structure of the K63-Ub2:tUIMs complex
To be Published

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