8EL1
| Structure of MBP-Mcl-1 in complex with ABBV-467 | 分子名称: | (7R,16R)-19,23-dichloro-10-{[2-(4-{[(2R)-1,4-dioxan-2-yl]methoxy}phenyl)pyrimidin-4-yl]methoxy}-1-(4-fluorophenyl)-20,22-dimethyl-16-[(4-methylpiperazin-1-yl)methyl]-7,8,15,16-tetrahydro-18,21-etheno-13,9-(metheno)-6,14,17-trioxa-2-thia-3,5-diazacyclononadeca[1,2,3-cd]indene-7-carboxylic acid, Maltose/maltodextrin-binding periplasmic protein,Induced myeloid leukemia cell differentiation protein Mcl-1, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose | 著者 | Judge, R.A, Judd, A.S, Souers, A.J. | 登録日 | 2022-09-22 | 公開日 | 2023-10-25 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.406 Å) | 主引用文献 | Selective MCL-1 inhibitor ABBV-467 is efficacious in tumor models but is associated with cardiac troponin increases in patients. Commun Med (Lond), 3, 2023
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8TNQ
| Cryo-EM structure of DDB1dB:CRBN:PT-179:SD40, conformation 1 | 分子名称: | 2-[(3S)-2,6-dioxopiperidin-3-yl]-5-(morpholin-4-yl)-1H-isoindole-1,3(2H)-dione, DNA damage-binding protein 1, Maltose/maltodextrin-binding periplasmic protein,SD40, ... | 著者 | Roy Burman, S.S, Hunkeler, M, Fischer, E.S. | 登録日 | 2023-08-02 | 公開日 | 2024-03-13 | 最終更新日 | 2024-04-03 | 実験手法 | ELECTRON MICROSCOPY (2.41 Å) | 主引用文献 | Continuous evolution of compact protein degradation tags regulated by selective molecular glues. Science, 383, 2024
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6TZC
| Crystal Structure of African Swine Fever Virus A179L with the Autophagy Regulator Beclin | 分子名称: | Apoptosis regulator Bcl-2 homolog, Beclin-1, Maltose/maltodextrin-binding periplasmic protein, ... | 著者 | Banjara, S, Kvansakul, M, Hinds, M.G. | 登録日 | 2019-08-12 | 公開日 | 2019-11-20 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.41 Å) | 主引用文献 | Crystal Structure of African Swine Fever Virus A179L with the Autophagy Regulator Beclin. Viruses, 11, 2019
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5I04
| Crystal structure of the orphan region of human endoglin/CD105 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Maltose-binding periplasmic protein,Endoglin, TRIETHYLENE GLYCOL, ... | 著者 | Saito, T, Bokhove, M, de Sanctis, D, Jovine, L. | 登録日 | 2016-02-03 | 公開日 | 2017-06-07 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.42 Å) | 主引用文献 | Structural Basis of the Human Endoglin-BMP9 Interaction: Insights into BMP Signaling and HHT1. Cell Rep, 19, 2017
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7VN2
| Crystal structure of MBP-fused BIL1/BZR1 (21-90) in complex with double-stranded DNA contaning ATCACGTGAT | 分子名称: | 1,2-ETHANEDIOL, DNA (5'-D(*TP*TP*AP*TP*CP*AP*CP*GP*TP*GP*AP*TP*AP*AP*A)-3'), Maltodextrin-binding protein,Protein BRASSINAZOLE-RESISTANT 1, ... | 著者 | Nosaki, S, Tanokura, M, Miyakawa, T. | 登録日 | 2021-10-10 | 公開日 | 2022-12-07 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.42 Å) | 主引用文献 | Brassinosteroid-induced gene repression requires specific and tight promoter binding of BIL1/BZR1 via DNA shape readout. Nat.Plants, 8, 2022
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7MK7
| Augmentor domain of augmentor-beta | 分子名称: | ALK and LTK ligand 1,Maltodextrin-binding protein, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose | 著者 | Krimmer, S.G, Reshetnyak, A.V, Puleo, D.E, Schlessinger, J. | 登録日 | 2021-04-21 | 公開日 | 2021-11-24 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.42815185 Å) | 主引用文献 | Structural basis for ligand reception by anaplastic lymphoma kinase. Nature, 600, 2021
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7ZYU
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4RWG
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6WBH
| Crystal structure of mRECK(CC4) in fusion with engineered MBP at medium resolution | 分子名称: | CHLORIDE ION, Maltodextrin-binding protein,Reversion-inducing cysteine-rich protein with Kazal motifs fusion, ZINC ION, ... | 著者 | Chang, T.H, Hsieh, F.L, Gabelli, S.B, Nathans, J. | 登録日 | 2020-03-26 | 公開日 | 2020-06-17 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.455 Å) | 主引用文献 | Structure of the RECK CC domain, an evolutionary anomaly. Proc.Natl.Acad.Sci.USA, 117, 2020
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4IKM
| X-ray structure of CARD8 CARD domain | 分子名称: | 1,2-ETHANEDIOL, IODIDE ION, Maltose-binding periplasmic protein, ... | 著者 | Jin, T, Huang, M, Smith, P, Jiang, J, Xiao, T. | 登録日 | 2012-12-26 | 公開日 | 2013-05-08 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.4606 Å) | 主引用文献 | The structure of the CARD8 caspase-recruitment domain suggests its association with the FIIND domain and procaspases through adjacent surfaces. Acta Crystallogr.,Sect.F, 69, 2013
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8VRS
| Mucin 16 peptide fused to MBP in complex with 4H11-scFv antibody | 分子名称: | 4H11 scFv chain, Maltose/maltodextrin-binding periplasmic protein,Mucin-16 | 著者 | Lee, K, Perry, K, Yeku, O.O, Spriggs, D.R. | 登録日 | 2024-01-22 | 公開日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.47 Å) | 主引用文献 | Structural basis for antibody recognition of the proximal MUC16 ectodomain. J Ovarian Res, 17, 2024
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8VG1
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8DX4
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6APX
| Crystal structure of human dual specificity phosphatase 1 catalytic domain (C258S) as a maltose binding protein fusion in complex with the monobody YSX1 | 分子名称: | GLYCEROL, Maltose-binding periplasmic protein,Dual specificity protein phosphatase 1, Monobody YSX1, ... | 著者 | Gumpena, R, Lountos, G.T, Sreejith, R.K, Tropea, J.E, Cherry, S, Waugh, D.S. | 登録日 | 2017-08-18 | 公開日 | 2017-11-01 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.491 Å) | 主引用文献 | Crystal structure of the human dual specificity phosphatase 1 catalytic domain. Protein Sci., 27, 2018
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6YBJ
| Structure of MBP-Mcl-1 in complex with compound 3e | 分子名称: | (2~{R})-2-[5-[3-chloranyl-2-methyl-4-[2-(4-methylpiperazin-1-yl)ethoxy]phenyl]-6-(5-fluoranylfuran-2-yl)thieno[2,3-d]pyrimidin-4-yl]oxy-3-[2-[(2-methylpyrazol-3-yl)methoxy]phenyl]propanoic acid, CHLORIDE ION, Maltose/maltodextrin-binding periplasmic protein,Induced myeloid leukemia cell differentiation protein Mcl-1, ... | 著者 | Dokurno, P, Surgenor, A.E, Murray, J.B. | 登録日 | 2020-03-17 | 公開日 | 2020-11-18 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Discovery of S64315, a Potent and Selective Mcl-1 Inhibitor. J.Med.Chem., 63, 2020
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8TNR
| Cryo-EM structure of DDB1dB:CRBN:PT-179:SD40, conformation 2 | 分子名称: | 2-[(3S)-2,6-dioxopiperidin-3-yl]-5-(morpholin-4-yl)-1H-isoindole-1,3(2H)-dione, DNA damage-binding protein 1, Maltose/maltodextrin-binding periplasmic protein,SD40, ... | 著者 | Roy Burman, S.S, Hunkeler, M, Fischer, E.S. | 登録日 | 2023-08-02 | 公開日 | 2024-03-13 | 最終更新日 | 2024-04-03 | 実験手法 | ELECTRON MICROSCOPY (2.5 Å) | 主引用文献 | Continuous evolution of compact protein degradation tags regulated by selective molecular glues. Science, 383, 2024
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6N85
| Resistance to inhibitors of cholinesterase 8A (Ric8A) protein in complex with MBP-tagged transducin-alpha residues 327-350 | 分子名称: | Maltose/maltodextrin-binding periplasmic protein,Guanine nucleotide-binding protein G(t) subunit alpha-2, Synembryn-A, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose | 著者 | Srivastava, D, Gakhar, L, Artemyev, N.O. | 登録日 | 2018-11-28 | 公開日 | 2019-07-10 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structural underpinnings of Ric8A function as a G-protein alpha-subunit chaperone and guanine-nucleotide exchange factor. Nat Commun, 10, 2019
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3A3C
| Crystal structure of TIM40/MIA40 fusing MBP, C296S and C298S mutant | 分子名称: | Maltose-binding periplasmic protein, LINKER, Mitochondrial intermembrane space import and assembly protein 40, ... | 著者 | Kawano, S, Naoe, M, Momose, T, Watanabe, N, Endo, T. | 登録日 | 2009-06-11 | 公開日 | 2009-08-04 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structural basis of yeast Tim40/Mia40 as an oxidative translocator in the mitochondrial intermembrane space. Proc.Natl.Acad.Sci.USA, 106, 2009
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1JVX
| Maltodextrin-binding protein variant D207C/A301GS/P316C cross-linked in crystal | 分子名称: | alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, maltodextrin-binding protein | 著者 | Srinivasan, U, Iyer, G.H, Przybycien, T.A, Samsonoff, W.A, Bell, J.A. | 登録日 | 2001-08-31 | 公開日 | 2001-09-12 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Crystine: Fibrous Biomolecular Material from Protein Crystals Cross-linked in a Specific Geometry Protein Eng., 15, 2002
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6QYN
| Structure of MBP-Mcl-1 in complex with compound 10d | 分子名称: | (2~{R})-2-[5-(3-chloranyl-2-methyl-4-oxidanyl-phenyl)-6-ethyl-thieno[2,3-d]pyrimidin-4-yl]oxy-3-phenyl-propanoic acid, Maltose/maltodextrin-binding periplasmic protein,Induced myeloid leukemia cell differentiation protein Mcl-1, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose | 著者 | Dokurno, P, Szlavik, Z, Ondi, L, Csekei, M, Paczal, A, Szabo, Z.B, Radics, G, Murray, J, Davidson, J, Chen, I, Davis, B, Hubbard, R.E, Pedder, C, Surgenor, A.E, Smith, J, Robertson, A, LeToumelin-Braizat, G, Cauquil, N, Zarka, M, Demarles, D, Perron-Sierra, F, Geneste, O, Kotschy, A. | 登録日 | 2019-03-09 | 公開日 | 2019-08-07 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structure-Guided Discovery of a Selective Mcl-1 Inhibitor with Cellular Activity. J.Med.Chem., 62, 2019
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1MG1
| HTLV-1 GP21 ECTODOMAIN/MALTOSE-BINDING PROTEIN CHIMERA | 分子名称: | CHLORIDE ION, PROTEIN (HTLV-1 GP21 ECTODOMAIN/MALTOSE-BINDING PROTEIN CHIMERA), alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose | 著者 | Kobe, B, Center, R.J, Kemp, B.E, Poumbourios, P. | 登録日 | 1999-03-01 | 公開日 | 1999-04-06 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Crystal structure of human T cell leukemia virus type 1 gp21 ectodomain crystallized as a maltose-binding protein chimera reveals structural evolution of retroviral transmembrane proteins. Proc.Natl.Acad.Sci.USA, 96, 1999
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5YEV
| Murine DR3 death domain | 分子名称: | SULFATE ION, TNFRSF25 death domain | 著者 | Yin, X, Jin, T. | 登録日 | 2017-09-19 | 公開日 | 2018-09-19 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Crystal structure and activation mechanism of DR3 death domain. Febs J., 286, 2019
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7JTR
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3N93
| Crystal structure of human CRFR2 alpha extracellular domain in complex with Urocortin 3 | 分子名称: | GLYCEROL, Maltose binding protein-CRFR2 alpha, Urocortin-3, ... | 著者 | Pal, K, Swaminathan, K, Pioszak, A.A, Xu, H.E. | 登録日 | 2010-05-28 | 公開日 | 2010-10-20 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structural basis of ligand selectivity in human CRFR1 and CRFR2 alpha extracellular domain To be Published
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1N3X
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