7ZYU

HDAC6 ZnF domain inhibitor - DARPin (Designed Ankyrin repeat protein) F10

Replaces:  7ATT

Summary for 7ZYU

• Entry DOI: 10.2210/pdb7zyu/pdb
• Descriptor: Histone deacetylase 6, Designed Ankyrin repeat protein F10, ZINC ION, ... (5 entities in total)
• Functional Keywords: darpin, zinc finger, de novo protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 2
• Total formula weight: 29833.94

Authors

Wang, L.,Kempf, G. (deposition date: 2022-05-25, release date: 2022-06-01, Last modification date: 2024-03-27)

• Primary citation: Wang, L.,Moreira, E.A.,Kempf, G.,Miyake, Y.,Oliveira Esteves, B.I.,Fahmi, A.,Schaefer, J.V.,Dreier, B.,Yamauchi, Y.,Alves, M.P.,Pluckthun, A.,Matthias, P.; Disrupting the HDAC6-ubiquitin interaction impairs infection by influenza and Zika virus and cellular stress pathways.; Cell Rep, 39:110736-110736, 2022; PubMed: 35476995; DOI: 10.1016/j.celrep.2022.110736

Experimental method

X-RAY DIFFRACTION (2.43 Å)