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7ZYU

HDAC6 ZnF domain inhibitor - DARPin (Designed Ankyrin repeat protein) F10

Replaces:  7ATT
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Histone deacetylase 6polymer11012279.01UniProt (Q9UBN7)
Pfam (PF02148)
Homo sapiens (human)HD6,Tubulin-lysine deacetylase HDAC6
2B
(B)
Designed Ankyrin repeat protein F10polymer16217172.51synthetic construct
3C, D, E
(A)
ZINC IONnon-polymer65.43Chemie (ZN)
4F, G, H
(A, B)
1,2-ETHANEDIOLnon-polymer62.13Chemie (EDO)
5I, J
(A, B)
waterwater18.010Chemie (HOH)
Sequence modifications
A: 1108 - 1215 (UniProt: Q9UBN7)
PDBExternal DatabaseDetails
Gly 1106-expression tag
Pro 1107-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight29451.5
Non-Polymers*Number of molecules6
Total formula weight382.4
All*Total formula weight29833.9
*Water molecules are not included.

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PDB entries from 2024-11-06

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