8VG1
Cryo-EM structure of FoxA1 and GATA4 in complex with ALBN1 nucleosome
Summary for 8VG1
Entry DOI | 10.2210/pdb8vg1/pdb |
EMDB information | 43197 |
Descriptor | Histone H3.1, Histone H4, Histone H2A type 1-B/E, ... (9 entities in total) |
Functional Keywords | nucleosome, pioneer transcription factors, dna binding proteins, transcription, chromatin, nuclear protein, nuclear protein-dna complex, nuclear protein/dna |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 12 |
Total formula weight | 362660.40 |
Authors | Zhou, B.R.,Bai, Y. (deposition date: 2023-12-22, release date: 2024-08-07, Last modification date: 2024-09-11) |
Primary citation | Zhou, B.R.,Feng, H.,Huang, F.,Zhu, I.,Portillo-Ledesma, S.,Shi, D.,Zaret, K.S.,Schlick, T.,Landsman, D.,Wang, Q.,Bai, Y. Structural insights into the cooperative nucleosome recognition and chromatin opening by FOXA1 and GATA4. Mol.Cell, 84:3061-, 2024 Cited by PubMed: 39121853DOI: 10.1016/j.molcel.2024.07.016 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (2.48 Å) |
Structure validation
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