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PDB: 222 件

6W4L
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The crystal structure of a single chain H2B-H2A histone chimera from Xenopus laevis
分子名称: Histone H2B 1.1,Histone H2A type 1, PYROPHOSPHATE
著者Warren, C, Bonanno, J.B, Almo, S.C, Shechter, D.
登録日2020-03-11
公開日2020-05-06
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.31 Å)
主引用文献Structure of a single-chain H2A/H2B dimer.
Acta Crystallogr.,Sect.F, 76, 2020
1KX5
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BU of 1kx5 by Molmil
X-Ray Structure of the Nucleosome Core Particle, NCP147, at 1.9 A Resolution
分子名称: CHLORIDE ION, DNA (5'(ATCAATATCCACCTGCAGATACTACCAAAAGTGTATTTGGAAACTGCTCCATCAAAAGGCATGTTCAGCTGGAATCCAGCTGAACATGCCTTTTGATGGAGCAGTTTCCAAATACACTTTTGGTAGTATCTGCAGGTGGATATTGAT)3'), DNA (5'(ATCAATATCCACCTGCAGATACTACCAAAAGTGTATTTGGAAACTGCTCCATCAAAAGGCATGTTCAGCTGGATTCCAGCTGAACATGCCTTTTGATGGAGCAGTTTCCAAATACACTTTTGGTAGTATCTGCAGGTGGATATTGAT)3'), ...
著者Davey, C.A, Sargent, D.F, Luger, K, Maeder, A.W, Richmond, T.J.
登録日2002-01-31
公開日2002-12-25
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (1.94 Å)
主引用文献Solvent Mediated Interactions in the Structure of the Nucleosome Core Particle at 1.9 A Resolution
J.Mol.Biol., 319, 2002
1KX3
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X-Ray Structure of the Nucleosome Core Particle, NCP146, at 2.0 A Resolution
分子名称: DNA (5'(ATCAATATCCACCTGCAGATTCTACCAAAAGTGTATTTGGAAACTGCTCCATCAAAAGGCATGTTCAGCTGAATTCAGCTGAACATGCCTTTTGATGGAGCAGTTTCCAAATACACTTTTGGTAGAATCTGCAGGTGGATATTGAT)3'), MANGANESE (II) ION, histone H2A.1, ...
著者Davey, C.A, Sargent, D.F, Luger, K, Maeder, A.W, Richmond, T.J.
登録日2002-01-31
公開日2002-12-25
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Solvent Mediated Interactions in the Structure of the Nucleosome Core Particle at 1.9 A Resolution
J.Mol.Biol., 319, 2002
1S32
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Molecular Recognition of the Nucleosomal 'Supergroove'
分子名称: 2-(2-CARBAMOYLMETHOXY-ETHOXY)-ACETAMIDE, 3-AMINO-(DIMETHYLPROPYLAMINE), 4-AMINO-(1-METHYLIMIDAZOLE)-2-CARBOXYLIC ACID, ...
著者Edayathumangalam, R.S, Weyermann, P, Gottesfeld, J.M, Dervan, P.B, Luger, K.
登録日2004-01-12
公開日2004-05-11
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Molecular Recognition of the Nucleosomal 'Supergroove'
Proc.Natl.Acad.Sci.USA, 101, 2004
3UTA
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BU of 3uta by Molmil
Crystal Structure of Nucleosome Core Particle Assembled with an Alpha-Satellite Sequence Containing Two TTAAA elements (NCP-TA2)
分子名称: 145-mer DNA, CHLORIDE ION, Histone H2A, ...
著者Chua, E.Y.D, Vasudevan, D, Davey, G.E, Wu, B, Davey, C.A.
登録日2011-11-25
公開日2012-04-11
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.07 Å)
主引用文献The mechanics behind DNA sequence-dependent properties of the nucleosome
Nucleic Acids Res., 40, 2012
3C1B
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BU of 3c1b by Molmil
The effect of H3 K79 dimethylation and H4 K20 trimethylation on nucleosome and chromatin structure
分子名称: Histone 2, H2bf, Histone H2A type 1, ...
著者Lu, X, Simon, M, Chodaparambil, J, Hansen, J, Shokat, K, Luger, K.
登録日2008-01-22
公開日2008-10-07
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献The effect of H3K79 dimethylation and H4K20 trimethylation on nucleosome and chromatin structure.
Nat.Struct.Mol.Biol., 15, 2008
6WZ5
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Bridging of double-strand DNA break activates PARP2/HPF1 to modify chromatin
分子名称: DNA (153-MER), Histone H2A, Histone H2B 1.1, ...
著者Halic, M, Bilokapic, S.
登録日2020-05-13
公開日2020-09-16
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (2.2 Å)
主引用文献Bridging of DNA breaks activates PARP2-HPF1 to modify chromatin.
Nature, 585, 2020
3UTB
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Crystal Structure of Nucleosome Core Particle Assembled with the 146b Alpha-Satellite Sequence (NCP146b)
分子名称: 146-mer DNA, Histone H2A, Histone H2B 1.1, ...
著者Chua, E.Y.D, Vasudevan, D, Davey, G.E, Wu, B, Davey, C.A.
登録日2011-11-25
公開日2012-04-11
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献The mechanics behind DNA sequence-dependent properties of the nucleosome
Nucleic Acids Res., 40, 2012
3UT9
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Crystal Structure of Nucleosome Core Particle Assembled with a Palindromic Widom '601' Derivative (NCP-601L)
分子名称: 145-mer DNA, CHLORIDE ION, Histone H2A, ...
著者Chua, E.Y.D, Vasudevan, D, Davey, G.E, Wu, B, Davey, C.A.
登録日2011-11-25
公開日2012-04-11
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献The mechanics behind DNA sequence-dependent properties of the nucleosome
Nucleic Acids Res., 40, 2012
1M19
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LIGAND BINDING ALTERS THE STRUCTURE AND DYNAMICS OF NUCLEOSOMAL DNA
分子名称: 3-AMINO-(DIMETHYLPROPYLAMINE), 4-AMINO-(1-METHYLIMIDAZOLE)-2-CARBOXYLIC ACID, 4-AMINO-(1-METHYLPYRROLE)-2-CARBOXYLIC ACID, ...
著者Suto, R.K, Edayathumangalam, R.S, White, C.L, Melander, C, Gottesfeld, J.M, Dervan, P.B, Luger, K.
登録日2002-06-18
公開日2003-02-18
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal Structures of Nucleosome Core Particles in Complex with Minor Groove DNA-binding Ligands
J.Mol.Biol., 326, 2003
7TN2
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BU of 7tn2 by Molmil
Composite model of a Chd1-nucleosome complex in the nucleotide-free state derived from 2.3A and 2.7A Cryo-EM maps
分子名称: Chromo domain-containing protein 1, DNA Lagging Strand, DNA Tracking Strand, ...
著者Nodelman, I.M, Bowman, G.D, Armache, J.-P.
登録日2022-01-20
公開日2022-03-02
最終更新日2024-02-21
実験手法ELECTRON MICROSCOPY (2.3 Å)
主引用文献Nucleosome recognition and DNA distortion by the Chd1 remodeler in a nucleotide-free state.
Nat.Struct.Mol.Biol., 29, 2022
1P3I
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Crystallographic Studies of Nucleosome Core Particles containing Histone 'Sin' Mutants
分子名称: Histone H2A, Histone H2B, Histone H3, ...
著者Muthurajan, U.M, Bao, Y, Forsberg, L.J, Edayathumangalam, R.S, Dyer, P.N, White, C.L, Luger, K.
登録日2003-04-17
公開日2004-02-24
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structures of histone Sin mutant nucleosomes reveal altered protein-DNA interactions
EMBO J., 23, 2004
5OMX
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X-ray Structure of the H2A-N38C Nucleosome Core Particle
分子名称: CHLORIDE ION, DNA (147-MER), Histone H2A, ...
著者Frouws, T.D, Richmond, T.J.
登録日2017-08-02
公開日2017-11-15
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.32 Å)
主引用文献Site-Specific Disulfide Crosslinked Nucleosomes with Enhanced Stability.
J. Mol. Biol., 430, 2018
4J8U
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BU of 4j8u by Molmil
X-ray structure of NCP145 with chlorido(eta-6-p-cymene)(N-phenyl-2-pyridinecarbothioamide)osmium(II)
分子名称: DNA, Histone H2A type 1, Histone H2B 1.1, ...
著者Adhireksan, Z, Davey, C.A.
登録日2013-02-15
公開日2013-04-17
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.38 Å)
主引用文献Novel metal(II) arene 2-pyridinecarbothioamides: a rationale to orally active organometallic anticancer agents
CHEM SCI, 4, 2013
4XZQ
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BU of 4xzq by Molmil
Nucleosome disassembly by RSC and SWI/SNF is enhanced by H3 acetylation near the nucleosome dyad axis
分子名称: DNA (147-MER), Histone H2A, Histone H2B 1.1, ...
著者Dechassa, M.L, Luger, K, Chatterjee, N, North, J.A, Manohar, M, Prasad, R, Ottessen, J.J, Poirier, M.G, Bartholomew, B.
登録日2015-02-04
公開日2015-10-14
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Histone Acetylation near the Nucleosome Dyad Axis Enhances Nucleosome Disassembly by RSC and SWI/SNF.
Mol.Cell.Biol., 35, 2015
1P3L
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BU of 1p3l by Molmil
Crystallographic Studies of Nucleosome Core Particles containing Histone 'Sin' Mutants
分子名称: Histone H2A, Histone H2B, Histone H3, ...
著者Muthurajan, U.M, Bao, Y, Forsberg, L.J, Edayathumangalam, R.S, Dyer, P.N, White, C.L, Luger, K.
登録日2003-04-17
公開日2004-02-24
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal structures of histone Sin mutant nucleosomes reveal altered protein-DNA interactions
EMBO J., 23, 2004
4J8W
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BU of 4j8w by Molmil
X-ray structure of NCP145 with chlorido(eta-6-p-cymene)(N-fluorophenyl-2-pyridinecarbothioamide)osmium(II)
分子名称: DNA (145-MER), Histone H2A, Histone H2B 1.1, ...
著者Adhireksan, Z, Davey, C.A.
登録日2013-02-15
公開日2013-04-17
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.41 Å)
主引用文献Novel metal(II) arene 2-pyridinecarbothioamides: a rationale to orally active organometallic anticancer agents
CHEM SCI, 4, 2013
1M18
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BU of 1m18 by Molmil
LIGAND BINDING ALTERS THE STRUCTURE AND DYNAMICS OF NUCLEOSOMAL DNA
分子名称: Histone H2A.1, Histone H2B.1, Histone H3.2, ...
著者Suto, R.K, Edayathumangalam, R.S, White, C.L, Melander, C, Gottesfeld, J.M, Dervan, P.B, Luger, K.
登録日2002-06-18
公開日2003-02-18
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Crystal Structures of Nucleosome Core Particles in Complex with Minor Groove DNA-binding Ligands
J.Mol.Biol., 326, 2003
4WU8
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BU of 4wu8 by Molmil
Structure of trPtNAP-NCP145
分子名称: DNA (145-MER), Histone H2A type 1, Histone H2B 1.1, ...
著者Chua, E.Y.D, Davey, C.A.
登録日2014-10-31
公開日2015-09-02
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Stereochemical control of nucleosome targeting by platinum-intercalator antitumor agents.
Nucleic Acids Res., 43, 2015
3MNN
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A Ruthenium Antitumour Agent Forms Specific Histone Protein Adducts in the Nucleosome Core
分子名称: 1,3,5-triaza-7-phosphatricyclo[3.3.1.1~3,7~]decane, 1-methyl-4-(1-methylethyl)benzene, DNA (145-MER), ...
著者Ong, M.S, Davey, C.A.
登録日2010-04-22
公開日2011-04-06
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献A ruthenium antimetastasis agent forms specific histone protein adducts in the nucleosome core
Chemistry, 17, 2011
7OHC
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Cryo-EM structure of nucleosome core particle composed of the Widom 601 DNA sequence
分子名称: DNA (145-MER), Histone H2A, Histone H2B 1.1, ...
著者Wang, H, Cramer, P.
登録日2021-05-10
公開日2021-07-28
最終更新日2024-07-10
実験手法ELECTRON MICROSCOPY (2.5 Å)
主引用文献Structures and implications of TBP-nucleosome complexes.
Proc.Natl.Acad.Sci.USA, 118, 2021
6ZHX
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Cryo-EM structure of the regulatory linker of ALC1 bound to the nucleosome's acidic patch: nucleosome class.
分子名称: Chromodomain-helicase-DNA-binding protein 1-like, DNA (145-MER) Widom 601 sequence, Histone H2A type 1, ...
著者Bacic, L, Gaullier, G, Croll, T.I, Deindl, S.
登録日2020-06-24
公開日2020-12-23
最終更新日2024-07-10
実験手法ELECTRON MICROSCOPY (2.5 Å)
主引用文献Mechanistic Insights into Regulation of the ALC1 Remodeler by the Nucleosome Acidic Patch.
Cell Rep, 33, 2020
3REH
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BU of 3reh by Molmil
2.5 Angstrom Crystal Structure of the Nucleosome Core Particle Assembled with a 145 bp Alpha-Satellite DNA (NCP145)
分子名称: DNA (145-MER), Histone H2A type 1, Histone H2B 1.1, ...
著者Wu, B, Davey, C.A.
登録日2011-04-04
公開日2012-03-14
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Specific DNA structural attributes modulate platinum anticancer drug site selection and cross-link generation.
Nucleic Acids Res., 39, 2011
4Z66
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BU of 4z66 by Molmil
Nucleosome disassembly by RSC and SWI/SNF is enhanced by H3 acetylation near the nucleosome dyad axis
分子名称: DNA (147-MER), Histone H2A, Histone H2B 1.1, ...
著者Dechassa, M.L, Luger, K, Chatterjee, N, North, J.A, Manohar, M, Prasad, R, Ottessen, J.J, Poirier, M.G, Bartholomew, B.
登録日2015-04-03
公開日2015-10-14
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Histone Acetylation near the Nucleosome Dyad Axis Enhances Nucleosome Disassembly by RSC and SWI/SNF.
Mol.Cell.Biol., 35, 2015
3REJ
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2.55 Angstrom Crystal Structure of the Nucleosome Core Particle Assembled with a 146 bp Alpha-Satellite DNA (NCP146b)
分子名称: DNA (146-MER), Histone H2A type 1, Histone H2B 1.1, ...
著者Wu, B, Davey, C.A.
登録日2011-04-04
公開日2012-03-14
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献Specific DNA structural attributes modulate platinum anticancer drug site selection and cross-link generation.
Nucleic Acids Res., 39, 2011

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件を2024-07-31に公開中

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