6ZHX

Cryo-EM structure of the regulatory linker of ALC1 bound to the nucleosome's acidic patch: nucleosome class.

Summary for 6ZHX

Entry DOI	10.2210/pdb6zhx/pdb
EMDB information	11220
Descriptor	Histone H3, Histone H4, Histone H2A type 1, ... (8 entities in total)
Functional Keywords	alc1, chd1l, chromatin remodeler, dna damage response, nucleosome, nuclear protein, gene regulation, dna binding protein
Biological source	Xenopus laevis (African clawed frog) More
Total number of polymer chains	12
Total formula weight	206785.14
Authors	Bacic, L.,Gaullier, G.,Croll, T.I.,Deindl, S. (deposition date: 2020-06-24, release date: 2020-12-23, Last modification date: 2021-07-14)
Primary citation	Lehmann, L.C.,Bacic, L.,Hewitt, G.,Brackmann, K.,Sabantsev, A.,Gaullier, G.,Pytharopoulou, S.,Degliesposti, G.,Okkenhaug, H.,Tan, S.,Costa, A.,Skehel, J.M.,Boulton, S.J.,Deindl, S. Mechanistic Insights into Regulation of the ALC1 Remodeler by the Nucleosome Acidic Patch. Cell Rep, 33:108529-108529, 2020 Cited by PubMed: 33357431 DOI: 10.1016/j.celrep.2020.108529 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (2.5 Å)

Structure validation