3QUK
 
 | | Crystal structures of the murine class I major histocompatibility complex H-2Db in complex with LCMV-derived gp33 altered peptide ligand (Y4A) | | 分子名称: | Beta-2-microglobulin, H-2 class I histocompatibility antigen, D-B alpha chain, ... | | 著者 | Allerbring, E, Duru, A.D, Uchtenhagen, H, Madhurantakam, C, Grimm, S, Tomek, M.B, Mazumdar, P.A, Spetz, A, Friemann, R, Sandalova, T, Uhlin, M, Nygren, P, Achour, A. | | 登録日 | 2011-02-24 | | 公開日 | 2012-03-21 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (2.41 Å) | | 主引用文献 | Unexpected T-cell recognition of an altered peptide ligand is driven by reversed thermodynamics.
Eur.J.Immunol., 42, 2012
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7P0A
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3TBS
 | | CRYSTAL STRUCTURE OF THE MURINE CLASS I MAJOR HISTOCOMPATIBILITY COMPLEX H-2DB IN COMPLEX THE WITH LCMV-DERIVED GP33 ALTERED PEPTIDE ligand (V3P,Y4A) | | 分子名称: | Beta-2-microglobulin, GLYCEROL, GLYCOPROTEIN G1, ... | | 著者 | Duru, A.D, Allerbring, E.B, Uchtenhagen, H, Mazumdar, P.A, Badia-Martinez, D, Madhurantakam, C, Sandalova, T, Nygren, P, Achour, A. | | 登録日 | 2011-08-08 | | 公開日 | 2012-08-08 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.49 Å) | | 主引用文献 | Conversion of a T cell viral antagonist into an agonist through higher stabilization and conserved molecular mimicry: Implications for TCR recognition
To be Published
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3CPL
 | | Crystal Structure of H-2Db in complex with a variant M6A of the NP366 peptide from influenza A virus | | 分子名称: | Beta-2-microglobulin, H-2 class I histocompatibility antigen, D-B alpha chain, ... | | 著者 | Kedzierska, K, Guillonneau, C, Hatton, L.A, Stockwell, D, Gras, S, Webby, R, Rossjohn, J, Purcell, A.W, Doherty, P.C, Turner, S.J. | | 登録日 | 2008-03-31 | | 公開日 | 2008-11-18 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Complete modification of TCR specificity and repertoire selection does not perturb a CD8+ T cell immunodominance hierarchy.
Proc.Natl.Acad.Sci.USA, 105, 2008
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4HUV
 | | Crystal Structure of H2Db-NPM6W | | 分子名称: | Beta-2-microglobulin, H-2 class I histocompatibility antigen, D-B alpha chain, ... | | 著者 | Gras, S, Twist, K.A, Rossjohn, J. | | 登録日 | 2012-11-04 | | 公開日 | 2013-02-27 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Preemptive priming readily overcomes structure-based mechanisms of virus escape.
Proc.Natl.Acad.Sci.USA, 110, 2013
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3TBY
 | | CRYSTAL STRUCTURE OF THE MURINE CLASS I MAJOR HISTOCOMPATIBILITY COMPLEX H-2DB IN COMPLEX WITH THE LCMV-DERIVED GP33 ALTERED PEPTIDE ligand (V3P, Y4F) | | 分子名称: | Beta-2-microglobulin, GLYCOPROTEIN GPC, H-2 class I histocompatibility antigen, ... | | 著者 | Duru, A.D, Allerbring, E.B, Uchtenhagen, H, Mazumdar, P.A, Badia-Martinez, D, Madhurantakam, C, Sandalova, T, Nygren, P, Achour, A. | | 登録日 | 2011-08-08 | | 公開日 | 2012-08-08 | | 最終更新日 | 2024-11-06 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Conversion of a T cell viral antagonist into an agonist through higher stabilization and conserved molecular mimicry: Implications for TCR recognition
To be Published
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7NA5
 | | Structure of the H2DB-TCR ternary complex with HSF2 melanoma neoantigen | | 分子名称: | 47BE7 TCR alpha chain, 47BE7 TCR beta chain, Beta-2-microglobulin, ... | | 著者 | Patskovsky, Y, Finnigan, J, Patskovska, L, Newman, J, Bhardwaj, N, Krogsgaard, M. | | 登録日 | 2021-06-19 | | 公開日 | 2022-06-22 | | 最終更新日 | 2024-10-09 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structure of the TCR-H2DB ternary complex with melanoma HSF2 neoantigen YGFRNVVHI
To be Published
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5JWD
 | | Crystal structure of H-2Db in complex with the LCMV-derived GP392-401 peptide | | 分子名称: | Beta-2-microglobulin, GLYCEROL, H-2 class I histocompatibility antigen, ... | | 著者 | Buratto, J, Badia-Martinez, D, Norstrom, M, Sandalova, T, Achour, A. | | 登録日 | 2016-05-12 | | 公開日 | 2017-05-24 | | 最終更新日 | 2024-11-13 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Crystal structures of H-2Db in complex with the LCMV-derived peptides GP92 and GP392 explain pleiotropic effects of glycosylation on antigen presentation and immunogenicity.
PLoS ONE, 12, 2017
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2CII
 | | The crystal structure of H-2Db complexed with a partial peptide epitope suggests an MHC Class I assembly-intermediate | | 分子名称: | BETA-2-MICROGLOBULIN, GLYCEROL, H-2 CLASS I HISTOCOMPATIBILITY ANTIGEN D-B ALPHA CHAIN, ... | | 著者 | Glithero, A, Tormo, J, Doering, K, Kojima, M, Jones, E.Y, Elliott, T. | | 登録日 | 2006-03-21 | | 公開日 | 2006-03-29 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | | 主引用文献 | The crystal structure of H-2D(b) complexed with a partial peptide epitope suggests a major histocompatibility complex class I assembly intermediate.
J. Biol. Chem., 281, 2006
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8TQA
 | | Crystal structure of Fab.28.14.8 in complex with MHC-I (H2-Db) | | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-2-microglobulin, ... | | 著者 | Jiang, J, Boyd, L.F, Natarajan, K, Margulies, D.H. | | 登録日 | 2023-08-06 | | 公開日 | 2024-03-20 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Experimental Structures of Antibody/MHC-I Complexes Reveal Details of Epitopes Overlooked by Computational Prediction.
J Immunol., 212, 2024
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3FTG
 | | Crystal Structure of H2Db in complex with NP366-N3A variant peptide from influenza | | 分子名称: | Beta-2-microglobulin, H-2 class I histocompatibility antigen, D-B alpha chain, ... | | 著者 | Gras, S, Guillonneau, C, Rossjohn, J. | | 登録日 | 2009-01-12 | | 公開日 | 2009-12-29 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Protective efficacy of cross-reactive CD8+ T cells recognising mutant viral epitopes depends on peptide-MHC-I structural interactions and T cell activation threshold.
Plos Pathog., 6, 2010
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1FFP
 | | CRYSTAL STRUCTURE OF MURINE CLASS I H-2DB COMPLEXED WITH PEPTIDE GP33 (C9M/K1S) | | 分子名称: | BETA-2 MICROGLOBULIN BETA CHAIN, H-2 CLASS I HISTOCOMPATIBILITY ANTIGEN, D-B, ... | | 著者 | Wang, B, Sharma, A, Maile, R, Saad, M, Collins, E.J, Frelinger, J.A. | | 登録日 | 2000-07-25 | | 公開日 | 2002-12-11 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Peptidic termini play a significant role in TCR recognition
J.IMMUNOL., 169, 2002
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4NSK
 | | CRYSTAL STRUCTURE OF THE MURINE CLASS I MAJOR HISTOCOMPATIBILITY COMPLEX H-2DB IN COMPLEX WITH LCMV-DERIVED GP33 ALTERED PEPTIDE ligand V3P | | 分子名称: | Beta-2-microglobulin, H-2 class I histocompatibility antigen, D-B alpha chain, ... | | 著者 | Allerbring, E.B, Duru, A.D, Uchtenhagen, H, Mazumdar, P.A, Badia-Martinez, D, Madhurantakam, C, Sandalova, T, Nygren, P, Achour, A. | | 登録日 | 2013-11-28 | | 公開日 | 2014-01-01 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | CRYSTAL STRUCTURE OF THE MURINE CLASS I MAJOR HISTOCOMPATIBILITY COMPLEX H-2DB IN COMPLEX WITH LCMV-DERIVED GP33 ALTERED PEPTIDE ligand V3P
TO BE PUBLISHED
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3BUY
 | | MHC-I in complex with peptide | | 分子名称: | Beta-2-microglobulin, H-2 class I histocompatibility antigen, D-B alpha chain, ... | | 著者 | Rossjohn, J, La Gruta, N.L, Purcell, A.W, Turner, S.J, Dunstone, M.A. | | 登録日 | 2008-01-03 | | 公開日 | 2008-03-25 | | 最終更新日 | 2024-11-13 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Epitope-specific TCRbeta repertoire diversity imparts no functional advantage on the CD8+ T cell response to cognate viral peptides
Proc.Natl.Acad.Sci.Usa, 105, 2008
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3CCH
 | | H-2Db complex with murine gp100 | | 分子名称: | Beta-2-microglobulin, GLYCEROL, H-2 class I histocompatibility antigen, ... | | 著者 | Badia-Martinez, D, Achour, A. | | 登録日 | 2008-02-25 | | 公開日 | 2009-03-10 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Design of agonistic altered peptides for the robust induction of CTL directed towards H-2Db in complex with the melanoma-associated epitope gp100.
Cancer Res., 69, 2009
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7P0T
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5SWZ
 | | Crystal Structure of NP1-B17 TCR-H2Db-NP complex | | 分子名称: | Beta-2-microglobulin, H-2 class I histocompatibility antigen, D-B alpha chain, ... | | 著者 | Gras, S, Del Campo, C.M, Farenc, C, Josephs, T.M, Rossjohn, J. | | 登録日 | 2016-08-09 | | 公開日 | 2016-10-05 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | | 主引用文献 | Reversed T Cell Receptor Docking on a Major Histocompatibility Class I Complex Limits Involvement in the Immune Response.
Immunity, 45, 2016
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1FFO
 | | CRYSTAL STRUCTURE OF MURINE CLASS I H-2DB COMPLEXED WITH SYNTHETIC PEPTIDE GP33 (C9M/K1A) | | 分子名称: | BETA-2 MICROGLOBULIN BETA CHAIN, H-2 CLASS I HISTOCOMPATIBILITY ANTIGEN, D-B, ... | | 著者 | Wang, B, Sharma, A, Maile, R, Saad, M, Collins, E.J, Frelinger, J.A. | | 登録日 | 2000-07-25 | | 公開日 | 2002-12-11 | | 最終更新日 | 2024-10-09 | | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | | 主引用文献 | Peptidic termini play a significant role in TCR recognition.
J.Immunol., 169, 2002
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1QLF
 | | MHC CLASS I H-2DB COMPLEXED WITH GLYCOPEPTIDE K3G | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, HUMAN BETA-2-MICROGLOBULIN, ... | | 著者 | Tormo, J, Jones, E.Y. | | 登録日 | 1999-08-30 | | 公開日 | 1999-09-01 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | | 主引用文献 | Crystal Structures of Two H-2Db/Glycopeptide Complexes Suggest a Molecular Basis for Ctl Cross-Reactivity
Immunity, 10, 1999
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2VE6
 | | Crystal structure of a Murine MHC class I H2-Db molecule in complex with a photocleavable peptide | | 分子名称: | BETA-2-MICROGLOBULIN, H-2 CLASS I HISTOCOMPATIBILITY ANTIGEN D-B ALPHA CHAIN, SENDAI VIRUS EPITOPE RESIDUES 324-332 MODIFIED AT P7 | | 著者 | Grotenbreg, G.M, Roan, N.R, Guillen, E, Meijers, R, Wang, J.H, Bell, G.W, Starnbach, M.N, Ploegh, H.L. | | 登録日 | 2007-10-17 | | 公開日 | 2008-01-22 | | 最終更新日 | 2024-11-13 | | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | | 主引用文献 | Discovery of Cd8+ T Cell Epitopes in Chlamydia Trachomatis Infection Through Use of Caged Class I Mhc Tetramers.
Proc.Natl.Acad.Sci.USA, 105, 2008
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7QNG
 | | Structure of a MHC I-Tapasin-ERp57 complex | | 分子名称: | Beta-2-microglobulin, H-2 class I histocompatibility antigen, D-B alpha chain, ... | | 著者 | Mueller, I.K, Thomas, C, Trowitzsch, S, Tampe, R. | | 登録日 | 2021-12-20 | | 公開日 | 2022-09-28 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Structure of an MHC I-tapasin-ERp57 editing complex defines chaperone promiscuity.
Nat Commun, 13, 2022
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1FFN
 | | CRYSTAL STRUCTURE OF MURINE CLASS I H-2DB COMPLEXED WITH PEPTIDE GP33(C9M) | | 分子名称: | BETA-2 MICROGLOBULIN, BETA CHAIN, H-2 CLASS I HISTOCOMPATIBILITY ANTIGEN, ... | | 著者 | Wang, B, Sharma, A, Maile, R, Saad, M, Collins, E.J, Frelinger, J.A. | | 登録日 | 2000-07-25 | | 公開日 | 2002-12-11 | | 最終更新日 | 2024-11-13 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Peptidic termini play a significant role in TCR recognition
J.IMMUNOL., 169, 2002
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3L3H
 | | X-ray crystal structure of the F6A mutant of influenza A acid polymerase epitope PA224 bound to murine H2-Db MHC | | 分子名称: | 10-mer peptide from Polymerase acidic protein, Beta-2-microglobulin, H-2 class I histocompatibility antigen, ... | | 著者 | Welland, A, Clements, C.S, Dunstone, M.A, Rossjohn, J. | | 登録日 | 2009-12-17 | | 公開日 | 2010-03-16 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Constraints within major histocompatibility complex class I restricted peptides: presentation and consequences for T-cell recognition
Proc.Natl.Acad.Sci.USA, 107, 2010
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1ZHB
 | | Crystal Structure Of The Murine Class I Major Histocompatibility Complex Of H-2Db, B2-Microglobulin, and a 9-Residue Peptide Derived from rat dopamine beta-monooxigenase | | 分子名称: | 9-mer peptide from Dopamine beta-monooxygenase, Beta-2-microglobulin, H-2 class I histocompatibility antigen, ... | | 著者 | Sandalova, T, Michaelsson, J, Harris, R.A, Odeberg, J, Schneider, G, Karre, K, Achour, A. | | 登録日 | 2005-04-25 | | 公開日 | 2005-06-14 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | A structural basis for CD8+ T cell-dependent recognition of non-homologous peptide ligands: implications for molecular mimicry in autoreactivity
J.Biol.Chem., 280, 2005
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2F74
 | | Murine MHC class I H-2Db in complex with human b2-microglobulin and LCMV-derived immunodminant peptide gp33 | | 分子名称: | Beta-2-microglobulin, H-2 class I histocompatibility antigen, D-B alpha chain, ... | | 著者 | Achour, A, Michaelsson, J, Harris, R.A, Ljunggren, H.G, Karre, K, Schneider, G, Sandalova, T. | | 登録日 | 2005-11-30 | | 公開日 | 2006-02-14 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Structural Basis of the Differential Stability and Receptor Specificity of H-2D(b) in Complex with Murine versus Human beta(2)-Microglobulin.
J.Mol.Biol., 356, 2006
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