3FTG
Crystal Structure of H2Db in complex with NP366-N3A variant peptide from influenza
Summary for 3FTG
Entry DOI | 10.2210/pdb3ftg/pdb |
Descriptor | H-2 class I histocompatibility antigen, D-B alpha chain, Beta-2-microglobulin, NP366-N3A variant peptide from influenza virus, ... (4 entities in total) |
Functional Keywords | h2db, mouse mhc, influenza, immunology, glycoprotein, immune response, membrane, mhc i, transmembrane, immunoglobulin domain, secreted, immune system |
Biological source | Mus musculus (mouse) More |
Cellular location | Membrane; Single-pass type I membrane protein: P01899 Secreted: P01887 |
Total number of polymer chains | 3 |
Total formula weight | 45419.93 |
Authors | Gras, S.,Guillonneau, C.,Rossjohn, J. (deposition date: 2009-01-12, release date: 2009-12-29, Last modification date: 2023-09-06) |
Primary citation | Valkenburg, S.A.,Gras, S.,Guillonneau, C.,La Gruta, N.L.,Thomas, P.G.,Purcell, A.W.,Rossjohn, J.,Doherty, P.C.,Turner, S.J.,Kedzierska, K. Protective efficacy of cross-reactive CD8+ T cells recognising mutant viral epitopes depends on peptide-MHC-I structural interactions and T cell activation threshold. Plos Pathog., 6:e1001039-e1001039, 2010 Cited by PubMed: 20711359DOI: 10.1371/journal.ppat.1001039 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.6 Å) |
Structure validation
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