7NA5

Structure of the H2DB-TCR ternary complex with HSF2 melanoma neoantigen

Summary for 7NA5

• Entry DOI: 10.2210/pdb7na5/pdb
• Descriptor: H-2 class I histocompatibility antigen, D-B alpha chain, Beta-2-microglobulin, Heat shock factor protein 2, ... (8 entities in total)
• Functional Keywords: neoantigen, cancer, melanoma, b16, mouse, h2db, tcr, tcr-mhc complex, anchor residue mutation, hsf2, immune system
• Biological source: Mus musculus (Mouse); More
• Total number of polymer chains: 5
• Total formula weight: 98383.68

Authors

Patskovsky, Y.,Finnigan, J.,Patskovska, L.,Newman, J.,Bhardwaj, N.,Krogsgaard, M. (deposition date: 2021-06-19, release date: 2022-06-22, Last modification date: 2023-10-18)

• Primary citation: Patskovsky, Y.,Finnigan, J.,Patskovska, L.,Newman, J.,Bhardwaj, N.,Krogsgaard, M.; Structure of the TCR-H2DB ternary complex with melanoma HSF2 neoantigen YGFRNVVHI; To be Published,

Experimental method

X-RAY DIFFRACTION (2.5 Å)