3QUK

Crystal structures of the murine class I major histocompatibility complex H-2Db in complex with LCMV-derived gp33 altered peptide ligand (Y4A)

Summary for 3QUK

• Entry DOI: 10.2210/pdb3quk/pdb
• Related: 1S7U 1S7V 1S7W 1S7X 3QUL
• Descriptor: H-2 class I histocompatibility antigen, D-B alpha chain, Beta-2-microglobulin, Pre-glycoprotein polyprotein GP complex, ... (4 entities in total)
• Functional Keywords: murine mhc, lcmv, receptor binding, beta2-microglobulin, immune system, t cell recognition, t cell receptor, cell surface
• Biological source: Mus musculus (Mouse); More
• Cellular location: Membrane; Single-pass type I membrane protein: P01899; Secreted: P01887; Glycoprotein G1: Virion membrane ; Peripheral membrane protein . Glycoprotein G2: Virion membrane ; Single-pass membrane protein . Stable signal peptide: Virion membrane ; Multi-pass membrane protein : P07399
• Total number of polymer chains: 6
• Total formula weight: 89490.39

Authors

Allerbring, E.,Duru, A.D.,Uchtenhagen, H.,Madhurantakam, C.,Grimm, S.,Tomek, M.B.,Mazumdar, P.A.,Spetz, A.,Friemann, R.,Sandalova, T.,Uhlin, M.,Nygren, P.,Achour, A. (deposition date: 2011-02-24, release date: 2012-03-21, Last modification date: 2023-09-13)

• Primary citation: Allerbring, E.B.,Duru, A.D.,Uchtenhagen, H.,Madhurantakam, C.,Tomek, M.B.,Grimm, S.,Mazumdar, P.A.,Friemann, R.,Uhlin, M.,Sandalova, T.,Nygren, P.A.,Achour, A.; Unexpected T-cell recognition of an altered peptide ligand is driven by reversed thermodynamics.; Eur.J.Immunol., 42:2990-3000, 2012; PubMed: 22837158; DOI: 10.1002/eji.201242588

Experimental method

X-RAY DIFFRACTION (2.41 Å)